Results 21 to 30 of about 4,966 (204)

Tetramethylpyrazine Ameliorates Peritoneal Angiogenesis by Regulating VEGF/Hippo/YAP Signaling

Frontiers in Pharmacology, 2021
Angiogenesis of human peritoneal vascular endothelial cells (HPVECs), linked to vascular endothelial growth factor (VEGF)/VEGF receptor 2 (VEGFR2) signaling, is a complication of peritoneal fibrosis (PF).
Xiaolin Zhu, Xiaolin Zhu, Yun Shan, Manshu Yu, Jun Shi, Lei Tang, Huimin Cao, Meixiao Sheng   +7 more
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Optimization of culture conditions for high yield tetramethylpyrazine Bacillus subtilis [PDF]

Zhongguo niangzao
A tetramethylpyrazine producing Bacillus subtilis q94, which was screened from light flavor (Qingxiangxing) Baijiu Daqu was used as the experimental strain.
DANG Ling, FAN Sanhong
doaj   +1 more source

Tetramethylpyrazine: A review on its mechanisms and functions

Biomedicine & Pharmacotherapy, 2022
Ligusticum chuanxiong Hort (known as Chuanxiong in China, CX) is one of the most widely used and long-standing medicinal herbs in China. Tetramethylpyrazine (TMP) is an alkaloid and one of the active components of CX. Over the past few decades, TMP has been proven to possess several pharmacological properties.
Jianguo, Lin, Qingqing, Wang, Simin, Zhou, Siyu, Xu, Kuiwu, Yao   +4 more
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Differences of fermentation performance of high-temperature Daqu in different production periods [PDF]

Zhongguo niangzao
The temperature, physicochemical indexes, microorganisms and tetramethylpyrazine during the fermentation process of high-temperature Daqu were monitored in different production periods (May, July, September, November 2023 and January 2024) in the hot and
CHEN Meimei, CHEN Fan, WEN Shangyu, MENG Tinglin, XIAO Zongyin, HUANG Xiaoping
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Tetramethylpyrazine Alleviates Behavioral and Psychological Symptoms of Dementia Through Facilitating Hippocampal Synaptic Plasticity in Rats With Chronic Cerebral Hypoperfusion

Frontiers in Neuroscience, 2021
Behavioral and psychological symptoms of dementia (BPSD) ubiquitously disturb all patients with dementia at some point in the disease course. Although a plethora of non-pharmacological and pharmacological methods targeting the relief BPSD have been ...
Zihu Tan, Zihu Tan, Jing Qiu, Jing Qiu, Yuting Zhang, Qiong Yang, Xixi Yin, Jia Li, Guangya Liu, Hengfei Li, Hengfei Li, Guang Yang, Guang Yang   +12 more
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Screening of high yield tetramethylpyrazine Bacillus from high temperature Daqu and its application in the stacking of fermented grains [PDF]

Zhongguo niangzao
In this study, Bacillus spp were screened from high temperature Daqu. The strains were preliminarily screened through high temperature resistance test and protease activity determination, rescreened by V-P test and tetramethylpyrazine content analysis ...
SHI Hongli, YU Mengting, WANG Shixin, ZHANG Peng, LIU Huimin, LI Chunmao, SHU Nanxin, SUN Pengpeng, LONG Daizhou, GUO Songbo
doaj   +1 more source

A Green Route for High-Yield Production of Tetramethylpyrazine From Non-Food Raw Materials

Frontiers in Bioengineering and Biotechnology, 2022
2,3,5,6-Tetramethylpyrazine (TMP) is an active pharmaceutical ingredient originally isolated from Ligusticum wallichii for curing cardiovascular and cerebrovascular diseases and is widely used as a popular flavoring additive in the food industry.
Jing Li, Jian Lu, Zhilin Ma, Jianxiu Li, Xianrui Chen, Mengxue Diao, Nengzhong Xie   +6 more
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A Danshensu-Tetramethylpyrazine Conjugate DT-010 Overcomes Multidrug Resistance in Human Breast Cancer

Frontiers in Pharmacology, 2019
Background: We previously demonstrated that a Danshensu-Tetramethylpyrazine conjugate DT-010 enhanced anticancer effect of doxorubicin (Dox) in Dox-sensitive human breast cancer cells, and protected against Dox-induced cardiotoxicity.
Xinhua Zhou, Anqi Wang, Anqi Wang, Liang Wang, Jianhua Yin, Jianhua Yin, Li Wang, Lijun Di, Maggie Pui-Man Hoi, Luchen Shan, Xu Wu, Xu Wu, Yuqiang Wang   +12 more
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Tetramethylpyrazine Ameliorates Lipopolysaccharide-Induced Sepsis in Rats via Protecting Blood–Brain Barrier, Impairing Inflammation and Nitrous Oxide Systems

Frontiers in Pharmacology, 2020
The aim of this study was to assess the underlying impact of Tetramethylpyrazine (TMP), which is the main activity compound of Ligusticum chuanxiong Hort, on the blood–brain barrier, inflammatory and nitrous oxide systems in a rat model of ...
Zi-Sheng Huang, Da-Qi Xie, Li-Jun Xu, Chang-Shun Huang, Min Zheng, Yi-Jun Chen, Yin Cao   +6 more
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The complete genome sequence of the thermophilic bacterium Laceyella sacchari FBKL4.010 reveals the basis for tetramethylpyrazine biosynthesis in Moutai‐flavor Daqu

MicrobiologyOpen, 2019
The genus Laceyella consists of a thermophilic filamentous bacteria. The pure isolate of Laceyella sacchari FBKL4.010 was isolated from Moutai‐flavor Daqu, Guizhou Province, China. In this study, the whole genome was sequenced and analyzed.
Dounan Li, Wei Huang, Chunxiao Wang, Shuyi Qiu   +3 more
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