Results 41 to 50 of about 3,816 (178)
Phytotherapy Research, EarlyView.The translational research framework integrating TCM for RA. The figure outlines a stepwise framework for the modernization and clinical translation of TCM in RA. Part 1 highlights the inheritance and development of TCM theory, including classical medical texts, traditional herbal knowledge, and syndrome differentiation–based treatment principles. Part
Jianting Wen +4 more
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Molecules, 2023 The excessive intake of fluoride, one of the trace elements required to maintain health, leads to liver injury. Tetramethylpyrazine (TMP) is a kind of traditional Chinese medicine monomer with a good antioxidant and hepatoprotective function.
Shuai Zhang +11 more
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Phytotherapy Research, EarlyView.ABSTRACT Vascular dementia (VaD), accounting for up to 20% of dementia cases globally, is primarily driven by chronic cerebral hypoperfusion (CCH), which leads to progressive cognitive impairment. Despite the increasing prevalence of VaD, effective treatments remain limited.
Jung‐Hoon Kim, Yongtaek Oh, Suin Cho
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Frontiers in Pharmacology, 2019 Recent published findings have demonstrated the effectiveness of combining molecules from traditional Chinese medicine with chemotherapeutic drugs to treat cancer.
Liang Zou +7 more
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Investigation of tetramethylpyrazine degradation in Rhodococcus sp. TMP1 bacteria. [PDF]
, 2013 The catabolism of alkylpyrazines is poorly described. The pathways for the degradation of di- and tri-substituted pyrazines have been proposed, but these related routes consistently include a hydroxylation step that cannot be performed on ...
Kutanovas, Simonas,
core
Advanced Materials, Volume 38, Issue 51, 11 September 2026.The new Cu‐containing MOF (Me2NH2)(CuICl2)@[Cu4(INA)4Cl2O]·1.5dmf (3) contains a cation and an anion as guests and shows UV‐near‐mid‐IR absorption and near‐IR emission. MOF 3 shows gas‐solid reactivity in the presence of NH3 and HCOOH to yield two new 3D MOF.
Rajat Saha +10 more
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Frontiers in Pharmacology, 2022 Ischemic stroke elicits white matter injury typically signed by axonal disintegration and demyelination; thus, the development of white matter reorganization is needed. 2,3,5,6-Tetramethylpyrazine (TMP) is widely used to treat ischemic stroke. This study
Xue-Feng Feng +18 more
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Puerarin‐Loaded Macrophage‐Derived Exosomes for Experimental Atherosclerosis
Food Frontiers, Volume 7, Issue 5, September 2026.We developed a macrophage‐derived exosome‐based delivery system to enhance the therapeutic efficacy of puerarin (Pue) against atherosclerosis (AS). Exosomes were isolated from RAW264.7 cells, co‐cultured with Pue, and comprehensively characterized for morphology, stability, and drug loading.
Zijian Zou +6 more
wiley +1 more source
Tetramethylpyrazine protects mitochondrial function by up-regulation of TFAM and inhibition of neuronal apoptosis in a rat model of surgical brain injury [PDF]
Iranian Journal of Basic Medical SciencesObjective(s): Mitochondrial dysfunction caused by mitochondrial DNA (mtDNA) damage and mutation is widely accepted as one of the pathological processes of neurodegenerative diseases. As an mtDNA binding protein, mitochondrial transcription factor A (TFAM)
Chaoyu Wang +5 more
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Frontiers in Pharmacology, 2021 Tetramethylpyrazine (TMP), a prominent ingredient of Chinese herb Ligusticum chuanxiong Hort, is known to suppress neuroinflammation and protect blood-brain barrier (BBB) integrity.
Zhuqing Jin +3 more
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