In order to increase and stabilize the content of tetramethylpyrazine in liquor, 13 strains of Bacillus were isolated from Maotai Daqu samples, and 5 strains with excellent protease production were selected through the preliminary screening of protease ...
Ying ZHANG +8 more
doaj +1 more source
Vascular Contributions to Cognitive Impairment and Treatments with Traditional Chinese Medicine [PDF]
published_or_final_versio
Chan, SW +7 more
core +1 more source
Tetramethylpyrazine Nitrone in Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial.
ImportanceTetramethylpyrazine nitrone has exhibited promising results in improving motor dysfunction in neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS).ObjectiveTo evaluate the safety and efficacy of orally administered tetramethylpyrazine nitrone in patients with ALS.Design, Setting, and ParticipantsThis phase 2, multicenter,
Liu X +22 more
europepmc +3 more sources
Production of tetra-methylpyrazine using engineered Corynebacterium glutamicum. [PDF]
Corynebacterium glutamicum ATCC 13032 is an established and industrially-relevant microbial host that has been utilized for the expression of many desirable bioproducts.
Chen, Yan +8 more
core
Optimisation of the post-harvest conditions to produce chocolate aroma from jackfruit seeds [PDF]
Jackfruit seeds are an under-utilized waste in many tropical countries. In this work, we demonstrate the potential of roasted jackfruit seeds to develop chocolate aroma.
Cabreira Ragazi, Gabriel +6 more
core +1 more source
Effects of Tetramethylpyrazine on Portal Hypertensive Rats
AbstractThe effects of tetramethylpyrazine, an alkaloid isolated from a Chinese herb Ligusticum wallichii Franch have been assessed in portal hypertensive rats.Portal hypertension was induced by partial portal vein ligation in Sprague-Dawley rats. Two weeks after ligation, when the hyperdynamic state had stabilized, rats were anaesthetized after an ...
F C, Chang +4 more
openaire +2 more sources
Tetramethylpyrazine Protects Mice against Thioacetamide-Induced Acute Hepatotoxicity
In this study, the intraperitoneal administration of 1 mg/kg thioacetamide (TAA) produced hepatotoxicity in mice. The increase in serum SGOT and SGPT produced at 24 h by this regimen was decreased in a dose-dependent manner by coadministration of tetramethylpyrazine (TMP; 10, 25 and 50 mg/kg).
Edmund C, So +4 more
openaire +2 more sources
Tetramethylpyrazine ameliorates acute lung injury by regulating the Rac1/LIMK1 signaling pathway
Acute lung injury (ALI) is a respiratory disorder characterized by severe inflammation of the alveoli and lung parenchyma. Tetramethylpyrazine (TMP), the main active compound in Ligusticum chuanxiong Hort (LC), can protect against lipopolysaccharide (LPS)
Simin Min +13 more
doaj +1 more source
Neurological and neurobehavioral assessment of experimental subarachnoid hemorrhage [PDF]
About 50% of humans with aneurysmal subarachnoid hemorrhage (SAH) die and many survivors have neurological and neurobehavioral dysfunction. Animal studies usually focused on cerebral vasospasm and sometimes neuronal injury.
Asma Tariq +6 more
core +2 more sources
Changes in free amino acid, peptide-N, sugar and pyrazine concentration during cocoa fermentation [PDF]
The free amino acids, peptide-N, reducing sugars (the flavour precursors in cocoa) and pyrazine profiles of mix hybrid cocoa beans fermented in a rotary drum reactor were monitored over a period of 6 days.
Ali, Asbi +3 more
core +2 more sources

