X-Ray, IR, NMR, UV-visible spectra and DFT analysis of 5-aryloxy-(1H)-tetrazoles, structure, conformation and tautomerism [PDF]
, 2014 The predominant tautomeric forms of N1–H, N2–H of 5-(2,6-dimethyl- and 5-(2,6-diisopropylphenoxy)-(1H)-tetrazoles were analyzed at B3LYP method using 6-311G(d,p) basis set in the gas phase.
Alireza Dadrass +8 more
core +1 more source
Synthesis of α-Sulfoximino Tetrazoles via Azido-Ugi Four-Component Reaction
SynOpen, 2022 The sulfoximine-based tetrazoles have been synthesized via azido-Ugi four-component reactions of sulfoximines, isocyanides, aldehydes, and TMS-azide in MeOH at 70 °C in the presence of InCl3.
C. P. Irfana Jesin +2 more
doaj +1 more source
Indium-Mediated Cleavage of the Trityl Group from Protected 1H-Tetrazoles [PDF]
, 2015 On treatment with indium metal in MeOH–THF, trityl groups undergo reductive removal from 1H-protected tetrazoles (including aliphatic, aromatic, and heteroaromatic substituents), affording the corresponding free tetrazoles in excellent yields, without ...
Behloul, Cherif +5 more
core +2 more sources
Frame-Shifted Synthesis of Oligoheterocycles as a Platform for Molecular Design. [PDF]
Angew Chem Int Ed EnglModern chemistry seeks to turn the simple raw materials into complex molecules that matter in health, agriculture, and technology. Among these, oligoheterocycles stand out for their versatility, yet they are most often built by cross‐coupling reactions that often rely on expensive metal catalysts.
Bastick KAC +6 more
europepmc +3 more sources
Журнал Белорусского государственного университета: Химия, 2022 Complexes [MII(2-pytz)Cl2] (M(II) = Pt, Pd; 2-pytz = 2-(tetrazol-1-yl)pyridine) were synthesised via direct interaction of the corresponding metal chlorides (K2PtCl4 or PdCl2) with 2-pytz under ambient conditions.
Tatiyana V. Serebryanskaya +5 more
doaj +1 more source
Regiospecific synthesis of N2-aryl 1,2,3-triazoles from 2,5-disubstituted tetrazoles via photochemically generated nitrile imine intermediates [PDF]
, 2014 The synthesis of N2-aryl 1,2,3-triazoles from 2,5-disubstituted tetrazoles was achieved under photochemical conditions. This simple and mild one-step reaction provides regiospecific access to 2,4,5-substituted 1,2,3-triazoles via a nitrile imine ...
Harris, Robert +2 more
core +1 more source
Materials Research Express, 2021 The current research represents a facile and competent methodology in the development of a novel magnetic nanocatalyst. This composite was synthesized by immobilizing La on Fe _3 O _4 nanoparticles pre-functionalized with tetrahydroharman-3-carboxylic ...
Taiebeh Tamoradi +3 more
doaj +1 more source
A versatile and an efficient synthesis of 5-substituted-1H-tetrazoles [PDF]
, 2011 A simple, efficient and a versatile method for the synthesis of 5-substituted-1H-tetrazoles by a [3+2]-cycloaddn. reaction of aryl nitriles with sodium azide in DMF using ZrOCl2·8 H2O as catalyst has been developed. The reactions work well at 100°C
Gowd Madhusudana Reddy Muthukur Bhoje, . +1 more
core +1 more source
Tetrazole containing 1,5-benzothiazepines: Design, synthesis, in silico and in vitro evaluation as medicinally potent ACE inhibitors [PDF]
Journal of Chemistry LettersIt is reported in literature that the key role of Angiotensin-I Converting Enzyme (ACE) is to convert angiotensin-I (Ang-I) to angiotensin-II (Ang-II) and to degrade bradykinin (BK) into the inactive metabolites.
Bhawani Singh, Ashok Suman
doaj +1 more source
Synthesis of N-Fmoc-ProtectedAmino Alkyl Thiocyanates/Selenocyanates and their Applicationin the Preparation of 5-Substituted S/Se-Linked Tetrazoles [PDF]
, 2011 A novel class of N-Fmoc-protected amino alkyl thiocy- anates/selenocyanates has been prepared by thiocyanation/seleno-cyanation of the corresponding alkyl iodides. These thiocyanates/selenocyanates undergo a facile [2+3]-cycloaddition reaction
Basavalingappa, P. Vasantha +2 more
core +1 more source