Results 21 to 30 of about 18,166 (271)

Ethyl 7-Acetyl-8a-methyl-3-(1-phenyl-1H-tetrazol-5-yl)-1,4,4a,5,6,8a-hexahydro-7H-pyrano[2,3-c]pyridazine-1-carboxylate

Molbank, 2022
The Diels–Alder reaction of ethyl 3-(1-phenyl-1H-tetrazol-5-yl-1,2-diaza-1,3-butadiene-1-carboxylate with 2-acetyl-6-methyl-2,3-dihydro-4H-pyran (methyl vinyl ketone dimer) regioselectively afforded the corresponding 3-(tetrazol-5-yl)-hexahydro-7H-pyrano[
Susana M. M. Lopes, Américo Lemos, José A. Paixão, Teresa M. V. D. Pinho e Melo   +3 more
doaj   +1 more source

Selective synthesis of ureas and tetrazoles from amides controlled by experimental conditions using conventional and microwave irradiation

Journal of Saudi Chemical Society, 2018
An efficient synthetic procedure has been achieved for selective synthesis of 1,5-disubstituted tetrazoles and diaryl ureas from secondary amides in situ in the presence of NaN3 and POCl3 as solvent, both by conventional and microwave methods.
Rajendran Sribalan, Andiappan Lavanya, Maruthan Kirubavathi, Vediappen Padmini   +3 more
doaj   +1 more source

Novel 1,2,3-Triazole-Coumarin Hybrid Glycosides and Their Tetrazolyl Analogues: Design, Anticancer Evaluation and Molecular Docking Targeting EGFR, VEGFR-2 and CDK-2

Molecules, 2022
This study represents the design and synthesis of a new set of triazole-coumarin-glycosyl hybrids and their tetrazole hybrid analogues possessing various sugar moieties and modified analogues. All the newly synthesized derivatives were screened for their
Wael A. El-Sayed, Fahad M. Alminderej, Marwa M. Mounier, Eman S. Nossier, Sayed M. Saleh, Asmaa F. Kassem   +5 more
doaj   +1 more source

Crystal structure of poly[di-μ-aqua-{5-[(1Z)-2-(4-chlorophenyl)-1-cyanoethenyl]-1,2,3,4-tetrazol-1-ido-κN1}sodium]

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, [Na(C10H5ClN5)(H2O)2]n, infinite chains of [Na(H2O)2]+ cations having a diamond-shaped cross-section and running parallel to the b axis are formed.
Joel T. Mague, Shaaban K. Mohamed, Mehmet Akkurt, Ahmed M. M. El-Saghier, Mustafa R. Albayati   +4 more
doaj   +1 more source

Antiprotozoal Activity of Azabicyclo-Nonanes Linked to Tetrazole or Sulfonamide Cores

Molecules, 2022
N-(Aminoalkyl)azabicyclo[3.2.2]nonanes possess antiplasmodial and antitrypanosomal activity. A series with terminal tetrazole or sulfonamido partial structure was prepared. The structures of all new compounds were confirmed by NMR and IR spectroscopy and
Johanna Dolensky, Clemens Hinteregger, Andreas Leitner, Werner Seebacher, Robert Saf, Ferdinand Belaj, Pascal Mäser, Marcel Kaiser, Robert Weis   +8 more
doaj   +1 more source

Photoinduced Porcine Gelatin Cross-Linking by Homobi- and Homotrifunctional Tetrazoles

Gels, 2021
Gelatin is a costless polypeptide material of natural origin, able to form hydrogels that are potentially useful in biomaterial scaffold design for drug delivery, cell cultures, and tissue engineering.
Luca Vaghi, Mauro Monti, Marcello Marelli, Elisa Motto, Antonio Papagni, Laura Cipolla   +5 more
doaj   +1 more source

Mechanistic DFT Study of 1,3-Dipolar Cycloadditions of Azides with Guanidine

Molecules, 2023
Density functional calculations SMD(chloroform)//B3LYP/6-311+G(2d,p) were employed in the computational study of 1,3-dipolar cycloadditions of azides with guanidine.
Ivana Antol, Zoran Glasovac, Davor Margetić   +2 more
doaj   +1 more source

Data on synthesis and structure–activity relationships of tetrazolato-bridged dinuclear platinum(II) complexes

Data in Brief, 2022
In this data file, the synthetic procedures for the preparation of a series of anticancer tetrazolato-bridged dinuclear platinum(II) complexes ([{cis-Pt(NH3)2}2(μ-OH)(μ-5-R-tetrazolato-N2,N3)]n+ (n = 1 or 2, tetrazolato-bridged complexes)) and of the ...
Seiji Komeda, Hiroki Yoneyama, Masako Uemura, Takahiro Tsuchiya, Miyuu Hoshiyama, Tomoya Sakazaki, Keiichi Hiramoto, Shinya Harusawa   +7 more
doaj  

Tetrazole containing 1,5-benzothiazepines: Design, synthesis, in silico and in vitro evaluation as medicinally potent ACE inhibitors [PDF]

Journal of Chemistry Letters
It is reported in literature that the key role of Angiotensin-I Converting Enzyme (ACE) is to convert angiotensin-I (Ang-I) to angiotensin-II (Ang-II) and to degrade bradykinin (BK) into the inactive metabolites.
Bhawani Singh, Ashok Suman
doaj   +1 more source

Synthesis of 5-Substituted 1H-Tetrazoles from Nitriles by Continuous Flow: Application to the Synthesis of Valsartan

Organic Process Research & Development, 2020
An efficient continuous flow process for the synthesis of 5-substituted 1H-tetrazoles is described.
Floriane Carpentier, F. Felpin, F. Zammattio, Erwan Le Grognec   +3 more
semanticscholar   +1 more source