Results 31 to 40 of about 45,106 (206)

Tetrodotoxin as a Tool to Elucidate Sensory Transduction Mechanisms: The Case for the Arterial Chemoreceptors of the Carotid Body

Marine Drugs, 2011
Carotid bodies (CBs) are secondary sensory receptors in which the sensing elements, chemoreceptor cells, are activated by decreases in arterial PO2 (hypoxic hypoxia).
Constancio Gonzalez, Ana Obeso, Ana Isabel Caceres, Asuncion Rocher   +3 more
doaj   +1 more source

Tetrodotoxin-Bupivacaine-Epinephrine Combinations for Prolonged Local Anesthesia

Marine Drugs, 2011
Currently available local anesthetics have analgesic durations in humans generally less than 12 hours. Prolonged-duration local anesthetics will be useful for postoperative analgesia.
Christina Bognet, Gabriel Corfas, David Zurakowski, Charles B. Berde, Barak Yahalom, Umeshkumar Athiraman   +5 more
doaj   +1 more source

Na(V)1.5 sodium channel window currents contribute to spontaneous firing in olfactory sensory neurons [PDF]

, 2014
Olfactory sensory neurons (OSNs) fire spontaneously as well as in response to odor; both forms of firing are physiologically important. We studied voltage-gated Na+ channels in OSNs to assess their role in spontaneous activity.
Dionne, Vincent E., Dupuis, Nicholas D., Finger, Thomas E., Frenz, Christopher T., Hansen, Anne, Levinson, Simon R., Shultz, Nicole   +6 more
core   +1 more source

Analysis of tetrodotoxin poisoning events in China from 2011 to 2020

Zhongguo shipin weisheng zazhi
ObjectiveTo analyze the epidemiological characteristics of tetrodotoxin poisoning events in China from 2011 to 2020 and provide a scientific basis for precise measures to prevent and control tetrodotoxin poisoning.MethodsDescriptive epidemiological ...
LIANG Junhua, HUANG Zheng, GUO Yunchang, FU Ping, LI Liefei, CHEN Lili, LI Ning, FAN Penghui, WEN Jian, LIU Jikai   +9 more
doaj   +1 more source

Tetrodotoxin Retention in the Toxic Goby Yongeichthys criniger

Journal of Marine Science and Engineering, 2022
To investigate tetrodotoxin (TTX) retention by the toxic goby Yongeichthys criniger, rearing experiments feeding nontoxic diets were conducted using 12 (Group I) and 17 (Group II) specimens collected from a natural environment.
Ryohei Tatsuno, Miwako Shikina, Yuta Yamamoto, Yoko Kanahara, Tomohiro Takatani, Osamu Arakawa   +5 more
doaj   +1 more source

Puffer Fish Gut Microbiota Studies Revealed Unique Bacterial Co-Occurrence Patterns and New Insights on Tetrodotoxin Producers

Marine Drugs, 2020
Tetrodotoxin (TTX) is a potent neurotoxin isolated mainly from toxic puffer fish. To date, the TTX biosynthetic mechanism inside its hosts remains unresolved.
Zhenchi Li, Jinglin Tian, Yukun Lai, Chiu-Hong Lee, Zongwei Cai, Chun-Fai Yu   +5 more
doaj   +1 more source

Tetrodotoxin and Its Analogues in Cephalothrix cf. simula (Nemertea: Palaeonemertea) from the Sea of Japan (Peter the Great Gulf): Intrabody Distribution and Secretions

Toxins, 2020
Some nemertean species from the genus Cephalothrix accumulate tetrodotoxin (TTX) in extremely high concentrations. The current study is the first to provide high-performance liquid chromatography–tandem mass spectrometry (HPLC–MS/MS) data on tetrodotoxin
Anna E. Vlasenko, Timur Yu. Magarlamov
doaj   +1 more source

Extracellular signal-regulated kinases mediate the enhancing effects of inflammatory mediators on resurgent currents in dorsal root ganglion neurons [PDF]

, 2019
Previously we reported that a group of inflammatory mediators significantly enhanced resurgent currents in dorsal root ganglion neurons. To understand the underlying intracellular signaling mechanism, we investigated the effects of inhibition of ...
Cummins, Theodore R., Knopp, Kelly L., Krajewski, Jeffrey L., McDermott, Jeff S., Nisenbaum, Eric S., Tan, Zhi-Yong, Wu, Bin   +6 more
core   +1 more source

Tetrodotoxin: Chemistry, Toxicity, Source, Distribution and Detection

Toxins, 2014
Tetrodotoxin (TTX) is a naturally occurring toxin that has been responsible for human intoxications and fatalities. Its usual route of toxicity is via the ingestion of contaminated puffer fish which are a culinary delicacy, especially in Japan.
Vaishali Bane, Mary Lehane, Madhurima Dikshit, Alan O'Riordan, Ambrose Furey   +4 more
doaj   +1 more source

Effect of channel block on the spiking activity of excitable membranes in a stochastic Hodgkin-Huxley model [PDF]

, 2004
The influence of intrinsic channel noise on the spontaneous spiking activity of poisoned excitable membrane patches is studied by use of a stochastic generalization of the Hodgkin-Huxley model.
Chow C C, Clay J R, DeFelice L J, Fox R F, G Schmid, Gammaitoni L, Goldman M S, Hille B, Hodgkin A L, Hänggi P, Hänggi P, I Goychuk, Lecar H, LeMasson G, P Hänggi, Press W H, Skaugen E, Strassberg A F   +17 more
core   +2 more sources