Modulation of ion channels as emerging therapeutic targets in the treatment of diabetic neuropathy. [PDF]
Gupta T +5 more
europepmc +1 more source
Effects of GLP-1 and GIP on cholinergic-induced contractility in isolated jejunal muscle from obese patients with and without type 2 diabetes mellitus. [PDF]
Malinauskas M +7 more
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Feral frogs, native newts, and chemical cues: identifying threats from and management opportunities for invasive African Clawed Frogs in Washington state. [PDF]
Anderson D +4 more
europepmc +1 more source
Cannabinoid-Driven Rewiring of GPCR and Ion Channel Signaling in Lung Cancer. [PDF]
Heriyanto DS +10 more
europepmc +1 more source
Effectiveness of physical therapy techniques for cancer-related pain: a systematic review. [PDF]
González-Ramírez IA +5 more
europepmc +1 more source
Possible Anti-Pain Vaccines: A Narrative Review of Emerging Strategies and Clinical Prospects. [PDF]
Martins YC +4 more
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AbstractThe identification of novel tetrodotoxin (TTX,1) analogues would significantly contribute to the elucidation of its biosynthetic pathway. In this study, the first C5–C10 directly bonded TTX analogues, 4,9‐anhydro‐10‐hemiketal‐5‐deoxyTTX (2) and 4,9‐anhydro‐8‐epi‐10‐hemiketal‐5,6,11‐trideoxyTTX (3), were found in the newtCynops ensicauda popeiby
Keiichi Konoki +2 more
exaly +3 more sources
Tetrodotoxin and its analogues profile in nemertean species from the sea of Japan
Toxicon, 2018For the first time search for tetrodotoxin (TTX) and its analogues in the extracts of nemerteans using HPLC-MS/MS was performed. TTX analogues were detected in two nemertean species in addition to TTX: 7 analogues were detected in the extract of Cephalothrix simula, 3 analogues - in the extract 11-norTTX of Kulikovia manchenkoi. Presence of 5-deoxyTTX,
Peter Velansky +2 more
exaly +3 more sources
Tetrodotoxin (TTX) is one of the most potent toxin already isolated, which occurs in a wide range of marine as well as terrestrial animals such as in newts and anurans. In this work, the occurrence of TTX and analogues was examined in three brachycephalid species: Brachycephalus ephippium, B. nodoterga and B. pernix using LC-FLD and LC-MS/MS.
Elisabeth Schwartz, CARLOS Bloch
exaly +3 more sources

