Results 71 to 80 of about 1,729 (152)

An Improved Synthesis of (−)-5,11-Dideoxytetrodotoxin

, 2016
We describe an improved synthesis of (−)-5,11-dideoxytetrodotoxin from an enone, which was used for synthesis of tetrodotoxin and its analogues in this laboratory.
Masaatsu Adachi (681653), Minoru Isobe (681655), Toshio Nishikawa (1991815), Takuya Imazu (1991812)   +3 more
core   +1 more source

Seafood cross-contamination by tetrodotoxin (TTX): management of an unusual route of exposure

In this study, liquid chromatography with tandem mass spectroscopy was applied to detect Tetrodotoxin and analogues (TTXs) on pufferfish (Sphoeroides marmoratus) tissues, accidentally found in the stomach of a cuttlefish (Sepia officinalis).
Malloggi C., Galli F., Giusti A., Dall'Ara S., Tinacci L., Armani A.   +5 more
core   +1 more source

Isolation of 6‑Deoxytetrodotoxin from the Pufferfish, Takifugu pardalis, and a Comparison of the Effects of the C‑6 and C‑11 Hydroxy Groups of Tetrodotoxin on Its Activity

, 2016
Identification of new tetrodotoxin (TTX, 1) analogues would be significant in the elucidation of its biosynthetic pathway and a study of its structure–activity relationships.
Yuta Kudo (1816669), Julian Finn (374947), Kohei Fukushima (1816666), Satsuki Sakugawa (1816660), Keiichi Konoki (1343721), Yuko Cho (1816657), Mari Yotsu-Yamashita (1816663)   +6 more
core   +1 more source

The mechanisms of enhancement and inhibition of field stimulation responses of guinea-pig vas deferens by prostacyclin analogues

, 1997
1. In the guinea-pig isolated vas deferens preparation bathed in Tyrode's solution, the prostacyclin analogues, cicaprost, TEI-9063, iloprost, taprostene and benzodioxane-prostacyclin, enhanced twitch responses to submaximal electrical field stimulation (
Chan, KM, Bourreau, JP, Tam, FSF, Jones, RL   +3 more
core   +1 more source

The effects of L-glutamate and its analogues upon the membrane conductance of central murine neurones in culture

, 1982
Neurones from brain and spinal cord of foetal mice were grown dissociated in monolayer cultures for 4–6 weeks prior to electropharmacological analysis.
J. F. MacDonald, J. M. Wojtowicz
core   +1 more source

Alexandrium spp.: From Toxicity to Potential Biotechnological Benefits. [PDF]

Mar Drugs, 2023
Montuori E, De Luca D, Penna A, Stalberga D, Lauritano C.   +4 more
europepmc   +1 more source

Use of sodium channel blockers for the treatment of preterm labor

, 2006
The present invention refers to the use of sodium channel blockers such as tetrodotoxin or saxitoxin, its analogues/derivatives as well as their acceptable salts, for the production of a medicament for the treatment of preterm labor and/or premature ...
Vela-Hernández, José Miguel, Candenas, M. Luz, Noheda Marín, Pedro, Buschmann, Helmut   +3 more
core  

Immunoassays, optical and electrochemical immunosensorsfor tetrodotoxin determination in puffer fish samples

, 2016
Tetrodotoxin (TTX) is a low molecular weight and potent marine neurotoxin which is usually present in some species of puffer fish. TTX selectively binds to voltage-sensitive sodium channels (VSGCs), blocking the influx of sodium into the cell and ...
del Rio, V, Campbell, Katrina; id_orcid, de la Iglesia, P, Kawatsu, K, Campas, Monica, Reverte, Laia, Katikou, P, Elliott, Christopher, Diogene, J, Rambla, M   +9 more
core  

After-hyperpolarizations produced in frog motoneurons by excitatory amino acid analogues.

, 1987
After-hyperpolarizations (AHPs) produced in frog motoneurons by applications of the excitatory amino acid analogues quisqualate (QUIS), N-methyl-D-aspartate (NMDA), and kainate (KA) were studied in the isolated hemisected frog spinal cord using sucrose ...
Holohean, A M, Wohlberg, C J, Hackman, J C, Davidoff, R A   +3 more
core  

Monthly Variation of Tetrodotoxin Levels in Pufferfish (Lagocephalus sceleratus) Caught from Antalya Bay, Mediterranean Sea. [PDF]

Mar Drugs, 2023
Kosker AR, Karakus M, Katikou P, Dal İ, Durmus M, Ucar Y, Ayas D, Özogul F.   +7 more
europepmc   +1 more source