Results 141 to 150 of about 15,357 (224)

Immunological function for TFEB [PDF]

Nature Immunology, 2014
openaire   +1 more source

TFEB-mediated autophagy stimulation as an anabolic strategy for bone: insights from TFEB activation in the osteoblast lineage

Autophagy Reports
Autophagy in the osteoblast lineage is essential for bone formation and skeletal homeostasis, yet the mechanisms through which it supports bone formation remain unclear. To investigate these mechanisms and evaluate the anabolic potential of autophagy stimulation, we generated a genetic mouse model in which transcription factor EB (Tfeb), a master ...
openaire   +2 more sources

TFEB wt Allele [PDF]

, 2020
openaire   +1 more source

Nuciferine Ameliorates Ovariectomy-Induced Bone Loss via TFEB-Mediated Autophagy-Lysosomal Pathway. [PDF]

Biomolecules
Shi B, Gao Z, Chen SY, Chen J, Wei L, Fan W, Yang Z, Zhang Y, Cui Y, Zhu X.   +9 more
europepmc   +1 more source

Oxidized LDL accelerates cartilage destruction and inflammatory chondrocyte death in osteoarthritis by disrupting the TFEB-regulated autophagy-lysosome pathway

Osteoarthritis (OA) involves cartilage degeneration, thereby causing inflammation and pain. Cardiovascular diseases, such as dyslipidemia, are risk factors for OA; however, the mechanism is unclear.
Lee, J., Um, In Gyu, Cho, M., Jhun, J., Woo, J., Na, H., Kim, S., Choi, J., Kim, Y., Shetty, A.   +9 more
core   +1 more source

Lutein Attenuates Lipid Accumulation in Association with TFEB Nuclear Translocation and Autophagy-Lysosomal Responses in a Cellular Model of Hepatic Steatosis. [PDF]

Antioxidants (Basel)
Saud F, Cabrera D, Valladares C, De la Fuente López M, Maldonado-Agurto R, Irribarra-Tapia D, Balboa E.   +6 more
europepmc   +1 more source

TFEB Protein Overexpression [PDF]

, 2020
openaire   +1 more source

TFEB perfects multitasking [PDF]

Nature Reviews Molecular Cell Biology, 2011
openaire   +1 more source

Network Toxicology Integrates In Vivo Evidence Linking Impaired Autophagic Clearance Involving the MTOR-TFEB Axis to Polystyrene Nanoplastic-Induced Neurotoxicity. [PDF]

Toxics
Tang N, Wang C, Zhang M, Li Y, Liang Y, Zhang J, Niu Q.   +6 more
europepmc   +1 more source

Noncanonical mTORC1-TFEB activation promotes hepatocyte plasticity and high-grade malignancy in hepatocellular carcinoma. [PDF]

J Clin Invest
Zhang C, Chao X, Williams SN, Wei X, DiGirolamo AM, Bajracharya A, Ma L, Huang M, Dunn N, Liu W, Ueda K, Sugimoto M, Ballabio A, Ni HM, Ding WX.   +14 more
europepmc   +1 more source