Results 101 to 110 of about 132,620 (281)

Risk Factors for Prostate Volume Progression After Prostate-Transurethral Resection

Research and Reports in Urology, 2020
Gede Wirya Kusuma Duarsa,1 Daniel Oktavianus Dau,1 Ida Bagus Putra Pramana,1 Pande Made Wisnu Tirtayasa,1 I Wayan Yudiana,1 Kadek Budi Santosa,1 Anak Agung Gde Oka,1 Tjokorda Gde Bagus Mahadewa,1 Christopher Ryalino2 1Department of Surgery, Faculty of ...
Duarsa GWK, Dau DO, Pramana IBP, Tirtayasa PMW, Yudiana IW, Santosa KB, Oka AAG, Mahadewa TGB, Ryalino C   +8 more
doaj  

TGFβ+ small extracellular vesicles from head and neck squamous cell carcinoma cells reprogram macrophages towards a pro‐angiogenic phenotype

Journal of Extracellular Vesicles, 2022
Transforming growth factor β (TGFβ) is a major component of tumor‐derived small extracellular vesicles (TEX) in cancer patients. Mechanisms utilized by TGFβ+ TEX to promote tumor growth and pro‐tumor activities in the tumor microenvironment (TME) are ...
Nils Ludwig, Saigopalakrishna S. Yerneni, Juliana H. Azambuja, Monika Pietrowska, Piotr Widłak, Cynthia S. Hinck, Alicja Głuszko, Mirosław J. Szczepański, Teresa Kärmer, Isabella Kallinger, Daniela Schulz, Richard J. Bauer, Gerrit Spanier, Steffen Spoerl, Johannes K. Meier, Tobias Ettl, Beatrice M. Razzo, Torsten E. Reichert, Andrew P. Hinck, Theresa L. Whiteside   +19 more
doaj   +1 more source

Additional file 4: of An evaluation of TAZ and YAP crosstalk with TGFβ signalling in canine osteosarcoma suggests involvement of hippo signalling in disease progression

, 2018
Table S1. Duplex Sequences. (DOCX 18 kb)
Luu, Anita, Schott, Courtney, Jones, Robert, Poon, Andrew, Golding, Brandon, Hamed, Roa’a, Deheshi, Benjamin, Mutsaers, Anthony, Wood, Geoffrey, Viloria-Petit, Alicia   +9 more
openaire   +1 more source

Packed for Ossification: High‐Density Bioprinting of hPDC Spheroids in HAMA Toward Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez, Maria Paula Marks, Paula Casademunt, Adrián Seijas‐Gamardo, Ioannis Papantoniou, Lorenzo Moroni, Carlos Mota   +6 more
wiley   +1 more source

MOESM4 of A novel approach for the generation of genetically modified mammary epithelial cell cultures yields new insights into TGFβ signaling in the mammary gland

, 2019
Authorsâ original file for figure ...
Kohn, Ethan, Du, Zhijun, Sato, Misako, Van Schyndle, Catherine, Welsh, Michael, Yang, Yu-an, Stuelten, Christina, Tang, Binwu, Ju, Wenjun, Bottinger, Erwin, Wakefield, Lalage   +10 more
openaire   +1 more source

High Throughput Determination of TGFβ1/SMAD3 Targets in A549 Lung Epithelial Cells

PLoS ONE, 2011
Transforming growth factor beta 1 (TGFβ1) plays a major role in many lung diseases including lung cancer, pulmonary hypertension, and pulmonary fibrosis. TGFβ1 activates a signal transduction cascade that results in the transcriptional regulation of genes in the nucleus, primarily through the DNA-binding transcription factor SMAD3.
Zhang, Y, Handley, D, Kaplan, T, Yu, H, Bais, AS, Richards, T, Pandit, KV, Zeng, Q, Benos, PV, Friedman, N, Eickelberg, O, Kaminski, N   +11 more
openaire   +5 more sources

Engineering Resatorvid‐Loaded Sub‐Microgels of Epigallocatechin‐3‐gallate/Hyaluronic Acid to Treat Acute Lung Injury

Advanced Healthcare Materials, EarlyView.
This study presents HAEP@Res sub‐microgels as a lung‐targeted delivery system integrating antioxidant activity with anti‐inflammatory therapy. The sub‐microgels demonstrate excellent biocompatibility, efficiently scavenge intracellular ROS, and downregulate pro‐inflammatory cytokines and genes in a Bleo‐induced ALI mouse model. These findings highlight
Bo Liu, Olawale Alimi Alimi, Benjamin Stearnes, Svetlana Romanova, Brady J. Sillman, Mena Asha Krishnan, Kristina Bailey, Benson J. Edagwa, Huanhuan Joyce Chen, Han‐jun Wang, Bin Duan   +10 more
wiley   +1 more source

Janus kinase 2 inhibition by pacritinib as potential therapeutic target for liver fibrosis

Hepatology, EarlyView., 2022
Diagram of the activation of the profibrotic and procontractile Janus kinase 2 (JAK2)/Ras homolog family member A/Rho‐kinase pathway and the inhibition of phosphorylated JAK2 by pacritinib to inhibit hepatic stellate cell activity. Abstract Background and Aims Janus kinase 2 (JAK2) signaling is increased in human and experimental liver fibrosis with ...
Sandra Torres, Cristina Ortiz, Nadine Bachtler, Wenyi Gu, Leon D. Grünewald, Nico Kraus, Robert Schierwagen, Christoph Hieber, Caroline Meier, Olaf Tyc, Maximilian Joseph Brol, Frank Erhard Uschner, Bart Nijmeijer, Christoph Welsch, Marie‐Luise Berres, Carmen Garcia‐Ruiz, Jose Carlos Fernandez‐Checa, Christian Trautwein, Thomas J. Vogl, Stefan Zeuzem, Jonel Trebicka, Sabine Klein   +21 more
wiley   +1 more source

Heterogeneous activation of the TGFβ pathway in glioblastomas identified by gene expression-based classification using TGFβ-responsive genes

Journal of Translational Medicine, 2009
Background TGFβ has emerged as an attractive target for the therapeutic intervention of glioblastomas. Aberrant TGFβ overproduction in glioblastoma and other high-grade gliomas has been reported, however, to date, none of these reports has systematically
Xu Xie L, Kapoun Ann M
doaj   +1 more source

Regulation of pancreatic cancer aggressiveness by stromal stiffening [PDF]

, 2016
No abstract ...
A Neesse, AD Rhim, BC Özdemir, H Laklai, I Barbieri, JJ Lee, JK Mouw, JM Bailey, Michael F Olson, Nicola Rath, P Bailey, SR Hingorani, SR Hingorani, V Sanz-Moreno   +13 more
core   +1 more source