Results 61 to 70 of about 138,672 (332)

MOESM2 of Gemcitabine reduces MDSCs, tregs and TGFβ-1 while restoring the teff/treg ratio in patients with pancreatic cancer

, 2016
Additional file 2: Table S1. Patient characteristics.
Eriksson, Emma, Wenthe, Jessica, Irenaeus, Sandra, Loskog, Angelica, Ullenhag, Gustav   +4 more
openaire   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Risk Factors for Prostate Volume Progression After Prostate-Transurethral Resection

Research and Reports in Urology, 2020
Gede Wirya Kusuma Duarsa,1 Daniel Oktavianus Dau,1 Ida Bagus Putra Pramana,1 Pande Made Wisnu Tirtayasa,1 I Wayan Yudiana,1 Kadek Budi Santosa,1 Anak Agung Gde Oka,1 Tjokorda Gde Bagus Mahadewa,1 Christopher Ryalino2 1Department of Surgery, Faculty of ...
Duarsa GWK, Dau DO, Pramana IBP, Tirtayasa PMW, Yudiana IW, Santosa KB, Oka AAG, Mahadewa TGB, Ryalino C   +8 more
doaj  

JNK-Dependent cJun Phosphorylation Mitigates TGFβ- and EGF-Induced Pre-Malignant Breast Cancer Cell Invasion by Suppressing AP-1-Mediated Transcriptional Responses

Cells, 2019
Transforming growth factor-β (TGFβ) has both tumor-suppressive and tumor-promoting effects in breast cancer. These functions are partly mediated through Smads, intracellular transcriptional effectors of TGFβ.
Anders Sundqvist, Oleksandr Voytyuk, Mohamed Hamdi, Herman E. Popeijus, Corina Bijlsma- van der Burgt, Josephine Janssen, John W.M. Martens, Aristidis Moustakas, Carl-Henrik Heldin, Peter ten Dijke, Hans van Dam   +10 more
doaj   +1 more source

PDGF-D expression is down-regulated by TGFβ in fibroblasts. [PDF]

PLoS ONE, 2014
Transforming growth factor-β (TGFβ) is a key mediator of fibrogenesis. TGFβ is overexpressed and activated in fibrotic diseases, regulates fibroblast differentiation into myofibroblasts and induces extracellular matrix deposition. Platelet-derived growth
Saima Charni Chaabane, Alexandra Coomans de Brachène, Ahmed Essaghir, Amélie Velghe, Sandra Lo Re, Julie Stockis, Sophie Lucas, Levon M Khachigian, François Huaux, Jean-Baptiste Demoulin   +9 more
doaj   +1 more source

MOESM1 of Gemcitabine reduces MDSCs, tregs and TGFβ-1 while restoring the teff/treg ratio in patients with pancreatic cancer

, 2016
Additional file 1. Gating strategies for flow cytometry.
Eriksson, Emma, Wenthe, Jessica, Irenaeus, Sandra, Loskog, Angelica, Ullenhag, Gustav   +4 more
openaire   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

TRANSFORMING GROWTH FACTOR Β IN BLOOD SERUM AND BRONCHOALVEOLAR LAVAGE FLUID IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Медицинская иммунология, 2014
. Progressive obstruction and lung tissue remodeling comprise an important feature of the airways in COPD patients. The main processes involved in tissue remodeling in COPD are protease/antiprotease, oxidant/antioxidant imbalances, like as inflammatory ...
E. A. Surkova, N. A. Kuzubova, T. P. Ses’, N. V. Egorova, Areg A. Totolian   +4 more
doaj   +1 more source

MOESM1 of Gene Expression Analysis Reveals Inhibition of Radiation-Induced TGFβ-Signaling by Hyperbaric Oxygen Therapy in Mouse Salivary Glands

, 2014
Supplementary material, approximately 307 KB.
Spiegelberg, Linda, Swagemakers, Sigrid, Ijcken, Wilfred Van, Oole, Edwin, Wolvius, Eppo, Essers, Jeroen, Braks, Joanna   +6 more
openaire   +1 more source

A novel approach for the generation of genetically modified mammary epithelial cell cultures yields new insights into TGFβ signaling in the mammary gland [PDF]

Breast Cancer Research, 2010
of A novel approach for the generation of genetically modified mammary epithelial cell cultures yields new insights into TGFβ signaling in the mammary ...
Kohn, Ethan A, Du, Zhijun, Sato, Misako, Van Schyndle, Catherine MH, Welsh, Michael A, Yang, Yu-an, Stuelten, Christina H, Tang, Binwu, Ju, Wenjun, Bottinger, Erwin P, Wakefield, Lalage M   +10 more
openaire   +3 more sources