Results 41 to 50 of about 132,620 (281)
Cells, 2019 Transforming growth factor-β (TGFβ) has both tumor-suppressive and tumor-promoting effects in breast cancer. These functions are partly mediated through Smads, intracellular transcriptional effectors of TGFβ.
Anders Sundqvist +10 more
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Biomedicines, 2022 Growth differentiation factor 15 (GDF15) is known as a TGFβ-like cytokine acting on the TGFβ receptor to modulate target genes. GDF15 is regarded as a tumor suppressor gene in the human bladder and the caffeic acid phenethyl ester (CAPE) induces GDF15 ...
Chen-Pang Hou +8 more
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The pituitary TGFb1 system as a novel target for the treatment of resistant prolactinomas [PDF]
, 2016 Prolactinomas are the most frequently observed pituitary adenomas and most of themrespond well to conventional treatment with dopamine agonists (DAs).
Camilletti, María Andrea +3 more
core +2 more sources
, 2018 Additional file 1. Table S1: Genes in KEGG TGFBeta-Signaling Pathway. Table S2. Differentially expressed mRNA in MSS tumors. Table S3. Differentially expressed mRNA in MSI tumors.
Pellatt, Andrew +6 more
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, 2015 Characteristics of colon cancer patient cohort randomly selected from Northwestern University for p21, TGFBR2, ACVR2, pERK, and pAkt staining. Ten patients did not have stage information available (X). (DOC 170 kb)
Bauer, Jessica +9 more
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Helicobacter pyloriinfection of human gastric epithelial cells induces IL-8 and TNFα, but not TGFβ1 mRNA [PDF]
FEMS Immunology & Medical Microbiology, 2000 Helicobacter pylori (Hp) infection causes gastric ulcers and gastric carcinomas. The mechanisms of these diseases are not known but Hp induction of cytokines is believed to be involved. However, the profile as well as the involvement of cytokines induced by Hp infection is less clear.
N, Nakachi +3 more
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Tranilast Inhibits Pulmonary Fibrosis by Suppressing TGFβ/SMAD2 Pathway
Drug Design, Development and Therapy, 2020 Motoyasu Kato,1,2 Fumiyuki Takahashi,1,2 Tadashi Sato,1,2 Yoichiro Mitsuishi,1,2 Ken Tajima,1,2 Hiroaki Ihara,1,2 Fariz Nurwidya,1,2 Hario Baskoro,1,2 Akiko Murakami,1,2 Isao Kobayashi,1,2 Moulid Hidayat,1,2 Naoko Shimada,1– 3 Shinichi Sasaki,1,2 ...
Kato M +17 more
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Медицинская иммунология, 2014 . Progressive obstruction and lung tissue remodeling comprise an important feature of the airways in COPD patients. The main processes involved in tissue remodeling in COPD are protease/antiprotease, oxidant/antioxidant imbalances, like as inflammatory ...
E. A. Surkova +4 more
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Protein phosphatase 5 modulates SMAD3 function in the transforming growth factor-beta pathway [PDF]
, 2012 Protein phosphatases play a key role in balancing the cellular responses to the transforming growth factor-beta (TGF beta) signals. Several protein phosphatases have been attributed roles in the regulation of the TGF beta pathway. Among these.
Bruce, David L. +4 more
core +3 more sources
Erk5 is a mediator to TGFβ1-induced loss of phenotype and function in human podocytes [PDF]
Frontiers in Pharmacology, 2014 Podocytes are highly specialized cells integral to the normal functioning kidney, however, in diabetic nephropathy injury occurs leading to a compromised phenotype and podocyte dysfunction which critically produces podocyte loss with subsequent renal impairment. TGFβ1 holds a major role in the development of diabetic nephropathy.
Badshah, Irbaz I. +2 more
openaire +3 more sources