Journal of Investigative Surgery, 2022 Background Tracheal stenosis (TS) is a complication of prolonged intubation, tracheotomy, and tracheal surgery that compromises the vascular supply. Animal models are essential for studying its pathophysiology and the effect of interventions.
Mariana Silva-Martínez +11 more
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Constitutively active transforming growth factor β receptor 1 in the mouse ovary promotes tumorigenesis [PDF]
, 2016 Despite the well-established tumor suppressive role of TGFβ proteins, depletion of key TGFβ signaling components in the mouse ovary does not induce a growth advantage.
Bartholin, Laurent +5 more
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Transforming growth factor-β in tumour development
Frontiers in Molecular Biosciences, 2022 Transforming growth factor-β (TGFβ) is a ubiquitous cytokine essential for embryonic development and postnatal tissue homeostasis. TGFβ signalling regulates several biological processes including cell growth, proliferation, apoptosis, immune function ...
Charles B. Trelford +3 more
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Tissue-specific calibration of extracellular matrix material properties by transforming growth factor-beta and Runx2 in bone is required for hearing [PDF]
, 2010 Publisher version: http://www.nature.com/embor/journal/v11/n10/full/embor2010135.htmlDA - 20100917 IS - 1469-3178 (Electronic) IS - 1469-221X (Linking) LA - ENG PT - JOURNAL ARTICLEDA - 20100917 IS - 1469-3178 (Electronic) IS - 1469-221X (Linking) LA ...
Alexandra E Porter +21 more
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The role of toll-like receptor 9 (TLR9) in Epstein-Barr virus-associated gastric cancer
Current Issues in Pharmacy and Medical Sciences, 2020 Epstein-Barr virus-associated gastric carcinoma (EBVaGC) is the most common malignancy caused by EBV infection. Toll-like receptors (TLRs) as major components of innate immune system are crucial in the development of inflammatory processes and ...
Dworzanska Anna +6 more
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Smad4 regulates growth plate matrix production and chondrocyte polarity. [PDF]
, 2017 Smad4 is an intracellular effector of the TGFβ family that has been implicated in Myhre syndrome, a skeletal dysplasia characterized by short stature, brachydactyly and stiff joints.
Alliston, Tamara +4 more
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TET2 Promotes Keloid Hyperplasia by Regulating 5hmC Modification in the TGFβ Promoter Region
Clinical, Cosmetic and Investigational Dermatology, 2023 Changying Niu,1 Shenxing Tan2 1Dermatological Department, Affiliated Hospital of Weifang Medical University, Weifang, People’s Republic of China; 2Plastic Surgery, Affiliated Hospital of Weifang Medical University, Weifang, People’s Republic of ...
Niu C, Tan S
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TUMOR NECROSIS AND TRANSFORMING GROWTH FACTORS LEVEL IN SUB-CLINICAL STAGE OF CHRONIC HEPATITIS C
Медицинская иммунология, 2014 . Participation of pro- and anti-inflammatory cytokines in pathogenesis of inflammation and fibrosis served as a basis for studying TNFα and TGFβ levels in blood serum from the patients with chronic hepatitis C (CHC), as compared with modes and degree of
T. V. Antonova +3 more
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Protein kinase CK2 in TGFβ-induced lens epithelial-mesenchymal transition
Biotechnology & Biotechnological Equipment, 2021 Cataract is a leading cause of reversible blindness. Secondary cataract is the result of migration, proliferation, and epithelial-mesenchymal transformation (EMT) of lens epithelial cells (LECs), induced by transforming growth factor β (TGFβ).
Alexander Oscar +9 more
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PTP4A1 promotes TGFβ signaling and fibrosis in systemic sclerosis. [PDF]
, 2017 Systemic sclerosis (SSc) is an autoimmune disease characterized by fibrosis of skin and internal organs. Protein tyrosine phosphatases have received little attention in the study of SSc or fibrosis.
Bai, Yunpeng +15 more
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