Способы расчета эффективного атомного номера многокомпонентного объекта [PDF]
, 2008 Recently, synthesis and secretion of connective tissue growth factor (CTGF)/CYR61/CTGF/NOV-family member 2 (CCN2) in cultures of hepatocytes were shown, which are sensitively up-regulated by exogenous TGF-β.
Gressner, Axel M. +6 more
core +1 more source
MicroRNA-483 amelioration of experimental pulmonary hypertension. [PDF]
, 2020 Endothelial dysfunction is critically involved in the pathogenesis of pulmonary arterial hypertension (PAH) and that exogenously administered microRNA may be of therapeutic benefit.
Bai, Liang +22 more
core +1 more source
Frizzled-8 integrates Wnt-11 and transforming growth factor-β signaling in prostate cancer [PDF]
, 2018 Wnt-11 promotes cancer cell migration and invasion independently of β-catenin but the receptors involved remain unknown. Here, we provide evidence that FZD8 is a major Wnt-11 receptor in prostate cancer that integrates Wnt-11 and TGF-β signals to promote
Carton, J +8 more
core +3 more sources
Jurnal Kedokteran Brawijaya, 2015 Infeksi cacing melalui kemampuannya memacu proliferasi sel T regulator dilaporkan dapat mempengaruhi manifestasi klinik dari alergi. Selain Interleukin (IL)-10, Transforming Growth Factor (TGF)-β merupakan sitokin yang di lepaskan oleh sel T regulator.
Nadiah Soleman Mukhasin +5 more
openaire +2 more sources
Inhibition of TGF-β Signaling Promotes Human Pancreatic β-Cell Replication. [PDF]
, 2016 Diabetes is associated with loss of functional pancreatic β-cells, and restoration of β-cells is a major goal for regenerative therapies. Endogenous regeneration of β-cells via β-cell replication has the potential to restore cellular mass; however ...
Bhushan, Anil +3 more
core +1 more source
Stable isotope metabolomics of pulmonary artery smooth muscle and endothelial cells in pulmonary hypertension and with TGF-beta treatment. [PDF]
, 2020 Altered metabolism in pulmonary artery smooth muscle cells (PASMCs) and endothelial cells (PAECs) contributes to the pathology of pulmonary hypertension (PH), but changes in substrate uptake and how substrates are utilized have not been fully ...
D' Alessandro, Angelo +12 more
core +1 more source
TGF-β receptor levels regulate the specificity of signaling pathway activation and biological effects of TGF-β [PDF]
, 2009 TGF-β is a pluripotent cytokine that mediates its effects through a receptor composed of TGF-β receptor type II (TGFBR2) and type I (TGFBR1). The TGF-β receptor can regulate Smad and nonSmad signaling pathways, which then ultimately dictate TGF-β's ...
Cress, Dean +3 more
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Bali Medical Journal, 2019 Background: Secondary hyperuricemia can increase the risk of renal dysfunction in the form of fibrosis and glomerulosclerosis mediated by TGF-β signalling. Non-pharmacological therapy through high dietary antioxidant intakes can help in controlling and preventing renal dysfunction by suppressing TGF-β expression.
Riska Nur Suci Ayu +2 more
openaire +1 more source
TGF-β2 dictates disseminated tumour cell fate in target organs through TGF-β-RIII and p38α/β signalling [PDF]
, 2013 In patients, non-proliferative disseminated tumour cells (DTCs) can persist in the bone marrow (BM) while other organs (such as lung) present growing metastasis.
Aguirre Ghiso, Julio A. +7 more
core +2 more sources
THU0004 MICRORNA-223 NEGATIVELY REGULATE GOUTY INFLAMMATION BY TARGETING THE NLRP3 INFLAMMASOME WITHOUT INFLUENCING IL-37 AND TGF-î'1 [PDF]
Annals of the Rheumatic Diseases, 2019 Background MicroRNA-223 (miR-223) serves as an important regulator of inflammatory and immune responses and is implicated in several auto-inflammatory disorders[1]. To date, no relevant studies have reported the expression levels of miR-223 in gout patients or assessed whether miR-223 participates in negatively regulating gouty inflammation via ...
Yu-Feng Qing +5 more
openaire +1 more source