Results 181 to 190 of about 230,695 (309)

Mitochondrial reactive oxygen species regulate acetyl-CoA flux between cytokine production and fatty acid synthesis in effector T cells. [PDF]

Cell Rep
Wu B, Woo JS, Hasiakos S, Pan C, Cokus S, Benincá C, Stiles L, Sun Z, Pellegrini M, Shirihai OS, Lusis AJ, Srikanth S, Gwack Y.   +12 more
europepmc   +1 more source

Interleukin-10 downregulates Mycobacterium tuberculosis-induced Th1 responses and CTLA-4 expression [PDF]

, 1996
Jianhua Gong, M Zhang, Robert L. Modlin, Peter S. Linsley, Dinakar Iyer, Y Lin, Peter F. Barnes   +6 more
openalex   +1 more source

Identification of Three Distinct Subgroups in Antiphospholipid Syndrome: Implication for Sex Differences and Prognostic Outcomes from a Multicenter Study

Advanced Science, Volume 12, Issue 15, April 17, 2025.
A large‐scale, multicenter, and two‐stage study is conducted to define antiphospholipid syndrome (APS) subgroups. By applying unsupervised K‐means clustering algorithm, the authors identified three distinct APS subgroups: obstetric APS, female thrombotic APS (tAPS), and male tAPS, which display marked differences in clinical manifestations and ...
Chen Chen, Ao Zhang, Jianhui Cheng, Zhongqiang Yao, Juan Meng, Yilu Qin, Qingyi Lu, Yufei Li, Xiangjun Liu, Tianhao Li, Chao Hou, Yundi Tang, Hongjiang Liu, Ning Xu, Sai Dong, Xinxin Li, Fangmin Xu, Jianping Guo, Chun Li   +18 more
wiley   +1 more source

The Role and Potential Application of IL-12 in the Immune Regulation of Tuberculosis. [PDF]

Int J Mol Sci
Wang H, Ruan G, Li Y, Liu X.
europepmc   +1 more source

M6A Modified miR‐31‐5p Suppresses M1 Macrophage Polarization and Autoimmune Dry Eye by Targeting P2RX7

Advanced Science, Volume 12, Issue 17, May 8, 2025.
The upregulation of FTO in autoimmune dry eye suppresses the recognition of pri‐miR‐31 by DGCR8, thereby inhibiting the maturation of miR‐31‐5p and reducing its inhibitory effect on the target gene P2RX7. The activation of P2RX7 subsequently triggers the p38 MAPK signaling pathway and increases the level of M1‐related genes, thus exacerbating the ...
Lu Zhao, Xuejia Li, Min Gao, Lin Liu, Binyun Ma, Xun Liu, Jiachen Zhang, Ruoxuan Liu, Bei Du, Ruihua Wei, Hong Nian   +10 more
wiley   +1 more source

Interleukin-16 enhances anti-tumor immune responses by establishing a Th1 cell-macrophage crosstalk through reprogramming glutamine metabolism in mice. [PDF]

Nat Commun
Wen Z, Liu T, Xu X, Acharya N, Shen Z, Lu Y, Xu J, Guo K, Shen S, Zhao Y, Wang P, Li S, Chen W, Li H, Ding Y, Shang M, Guo H, Hou Y, Cui B, Shen M, Huang Y, Pan T, Qingqing W, Cao Q, Wang K, Xiao P.   +25 more
europepmc   +1 more source

Expression and Function of CTLA-4 in Th1 and Th2 Cells [PDF]

, 1998
Maria‐Luisa Alegre, Helena Shiels, Craig B. Thompson, Thomas F. Gajewski   +3 more
openalex   +1 more source

An Off‐the‐Shelf Artificial Proregenerative Macrophage for Pressure Ulcer Treatment

Advanced Science, EarlyView.
Artificial macrophages (artM) by encapsulating M2 lysates into biodegradable PLGA microspheres and coated with macrophage membrane, are engineered as new therapeutics against skin pressure ulcer. In mouse models, the artM exhibited robust tissue repair through cell recruitment and microenvironment modulation, showing great therapeutic potential for ...
Qi Su, Jingrong Wang, Yini Huangfu, Rui Gao, Pengxu Kong, Yu Gao, Huijuan Song, Ju Zhang, Pingsheng Huang, Chuangnian Zhang, Zujian Feng, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Malassezia Globosa Aggravates Atopic Dermatitis by Influencing the Th1/Th2 Related Cytokines in Mouse Models. [PDF]

Clin Cosmet Investig Dermatol
Wu Z, Yu H, Chen Z, Liu W, Xia P.
europepmc   +1 more source

Levels of IL-12 in the sera of patients with systemic lupus erythematosus (SLE)—relation to Th1- and Th2-derived cytokines [PDF]

, 1999
Yoshiaki Tokano, Shinji Morimoto, Hiroyuki Kaneko, Hirofumi Amano, Kazuki Nozawa, Yoshinari Takasaki, Hiroshi Hashimoto   +6 more
openalex   +1 more source