ABSTRACT Objective Tofacitinib is a Janus kinase (JAK) inhibitor approved for the treatment of moderate‐to‐severe rheumatoid arthritis (RA). However, its synovium‐related molecular mechanisms, particularly its regulatory effect on fibroblast‐like synoviocyte (FLS) migration, remain incompletely understood.
Shuqi Fang +13 more
wiley +1 more source
The effect of voluntary chronic alcohol consumption on Th1/Th2 cytokine signature during adolescence in Sprague-Dawley Rats. [PDF]
Moeketsi K +5 more
europepmc +1 more source
The language of the immune system: Part 1: Cytokine conversations and conversationalists. [PDF]
Rosenthal KS.
europepmc +1 more source
Selective Anti-Inflammatory Actions of Curcumin on Cytokine Pathways in Major Depressive Disorder. [PDF]
Chen T +6 more
europepmc +1 more source
Generating Patient-Specific Anti-Tumor Responses with Non-Genetically Altered 'Off-the-Shelf' Allogeneic Cell Therapy: Leveraging Allo-Incompatibility for In Situ Vaccination. [PDF]
Har-Noy M.
europepmc +1 more source
Reduced inflammatory and Th1 transcriptional profiles in geriatric versus adult cotton rats infected with respiratory syncytial virus. [PDF]
Miller J +8 more
europepmc +1 more source
The Framework of Host Innate and Adaptive Immunological Pathways. [PDF]
Hu WC.
europepmc +1 more source
Revisiting the Th1/Th2 Paradigm [PDF]
The identification of subsets of CD4+ helper cells producing distinct pattern of cytokines has provided a valuable framework for understanding how different effector populations of immune cells can be recruited in vivo during infection. In the view of most investigators, Th1 and Th2 cells produce factors that serve as their own autocrine factors and ...
Muraille, Eric, Leo, Oberdan
openaire +2 more sources

