Results 231 to 240 of about 304,659 (296)

Tofacitinib Regulates β‐Catenin Nuclear Translocation to Inhibit FLS Migration and Alleviate Clinical Symptoms of RA

open access: yesiNew Medicine, EarlyView.
ABSTRACT Objective Tofacitinib is a Janus kinase (JAK) inhibitor approved for the treatment of moderate‐to‐severe rheumatoid arthritis (RA). However, its synovium‐related molecular mechanisms, particularly its regulatory effect on fibroblast‐like synoviocyte (FLS) migration, remain incompletely understood.
Shuqi Fang   +13 more
wiley   +1 more source

Reduced inflammatory and Th1 transcriptional profiles in geriatric versus adult cotton rats infected with respiratory syncytial virus. [PDF]

open access: yesPLoS Pathog
Miller J   +8 more
europepmc   +1 more source

Revisiting the Th1/Th2 Paradigm [PDF]

open access: possibleScandinavian Journal of Immunology, 1998
The identification of subsets of CD4+ helper cells producing distinct pattern of cytokines has provided a valuable framework for understanding how different effector populations of immune cells can be recruited in vivo during infection. In the view of most investigators, Th1 and Th2 cells produce factors that serve as their own autocrine factors and ...
Muraille, Eric, Leo, Oberdan
openaire   +2 more sources

Home - About - Disclaimer - Privacy