Results 221 to 230 of about 318,750 (310)

The Effects of Biologic Agents on Carotid Intima‐Media Thickness and Hepatic Steatosis in Patients With Moderate‐To‐Severe Psoriasis: A Prospective Observational Cohort Study

open access: yesJEADV Clinical Practice, EarlyView.
In this prospective observational cohort study, 34 patients with moderate‐to‐severe psoriasis received biologic therapy (anti‐TNF‐α, anti‐IL‐12/23, or anti‐IL‐17) for 6 months. Carotid intima–media thickness decreased significantly in the overall cohort (p < 0.01), with the greatest reductions in the anti‐IL‐17 and anti‐IL‐12/23 groups.
Harika Ödemiş   +6 more
wiley   +1 more source

Single-allele chromatin tracing reveals cytokine-dependent super-enhancer repositioning in CD4<sup>+</sup> T cells. [PDF]

open access: yesImmunity
Jay A   +10 more
europepmc   +1 more source

Not Just Mycosis Fungoides: A Case Series of Concurrent Fungal Infections in Patients With Cutaneous T‐Cell Lymphoma

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Mycosis fungoides is a misnomer that means ‘mushroom‐like fungal disease’, but it is, in fact, the most common form of cutaneous T‐cell lymphoma. The diagnosis of mycosis fungoides is often delayed due to non‐specific symptoms and cutaneous signs that mimic other common benign inflammatory dermatoses.
Ji Fung Yong   +5 more
wiley   +1 more source

Th2/Th17 Inflammation: Pathogenic Drivers and Therapeutic Targets in Darier and Hailey‐Hailey Diseases

open access: yesJEADV Clinical Practice, EarlyView.
Skin samples of Hailey‐Hailey and Darier diseases were analyzed for inflammatory and barrier markers using indirect immunofluorescence and transcriptomic techniques. A mixed Th2/Th17 inflammatory pattern and altered expression of barrier markers were observed.
Ella Glodjajic   +10 more
wiley   +1 more source

Mechanism of RNA‐Binding Protein ELAVL1 in Promoting Th2 Cell Differentiation Through Stabilizing CPA3 mRNA in Allergic Rhinitis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study aimed to elucidate the role of the RNA‐binding protein embryonic lethality abnormal vision‐like protein 1 (ELAVL1) in the pathogenesis of allergic rhinitis (AR), specifically by investigating its potential to promote T helper 2 (Th2) cell differentiation by regulating the stability of carboxypeptidase A3 (CPA3) mRNA.
Meng‐Ya Liu   +2 more
wiley   +1 more source

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