Results 281 to 290 of about 528,953 (331)
Some of the next articles are maybe not open access.
2011
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???????????? ?????????????????? ???????????????????????? ?????????????????? ?????????????????????? ?????????????????? ?? ???????? ?????????????????? ???????????? ?????? ?????????????????? ???????????? ????????-???????????????????? ?????????? ?????????????????????? ???????????? TNF-??, INF-?? ?? IL-2 ?? ?????????????????? ??????????. ????????????????????
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A role for Th1‐like Th17 cells in the pathogenesis of inflammatory and autoimmune disorders
Molecular Immunology, 2019HighlightsEvidences for Th17 cells plasticity are reviewed.Highlights the importance of Th17 cells plasticity in immune diseases.Th1‐like Th17 cells play pivotal role in autoimmune disorders. Abstract The T helper 17 (Th17) cells contain a dynamic subset
A. N. Kamali +6 more
semanticscholar +1 more source
Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells.
Journal of Immunology, 1995Dendritic cells are APCs that are unique in their potency to stimulate proliferation of primary Ag-specific responses in vitro and in vivo. In this study, we demonstrate that dendritic cells can produce IL-12, a dominant cytokine involved in the ...
S. Macatonia +9 more
semanticscholar +1 more source
Journal of Theoretical Biology, 1994
We present and analyze a model for the cross-regulation of the Th1 and Th2 helper cell subsets during an immune response by the regulatory cytokines interferon-gamma (IFN)-gamma) and interleukin-10 (IL-10). IFN-gamma, secreted by Th1 cells, can inhibit the proliferation of Th2 cells.
M A, Fishman, A S, Perelson
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We present and analyze a model for the cross-regulation of the Th1 and Th2 helper cell subsets during an immune response by the regulatory cytokines interferon-gamma (IFN)-gamma) and interleukin-10 (IL-10). IFN-gamma, secreted by Th1 cells, can inhibit the proliferation of Th2 cells.
M A, Fishman, A S, Perelson
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Sarcoidosis and Th1 chemokines.
La Clinica terapeutica, 2015Many studies have shown high levels of the chemokine Interferon-γ-inducible protein 10 (IP-10) and its chemokine (C-X-C motif) receptor (CXCR) 3, expressed on Type-1 helper (Th1) lymphocytes, in bronchoalveolar lavage (BAL) and biopsy samples of patients with sarcoidosis.
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Current Opinion in Hematology, 2001
After activation, CD4 helper T (Th) cells differentiate into Th1or Th2 effector subsets. These two types of cells produce distinct profiles of cytokines and regulate different immune responses. This review summarizes recent progress on different features of co-stimulatory regulation and chemokine-mediated homing of Th1 and Th2 cells.
C, Dong, R A, Flavell
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After activation, CD4 helper T (Th) cells differentiate into Th1or Th2 effector subsets. These two types of cells produce distinct profiles of cytokines and regulate different immune responses. This review summarizes recent progress on different features of co-stimulatory regulation and chemokine-mediated homing of Th1 and Th2 cells.
C, Dong, R A, Flavell
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Zeitschrift fur Rheumatologie, 2012
T helper cells contribute to the induction and maintenance of rheumatic inflammation through the secretion of cytokines. The analysis of Th1 cells expressing interferon-γ, Th17 cells expressing interleukin-17 and the newly described Th1+17 cells could give insight into the pathophysiological mechanisms of rheumatic diseases.
H-D, Chang, T, Kamradt, H, Schulze-Koops
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T helper cells contribute to the induction and maintenance of rheumatic inflammation through the secretion of cytokines. The analysis of Th1 cells expressing interferon-γ, Th17 cells expressing interleukin-17 and the newly described Th1+17 cells could give insight into the pathophysiological mechanisms of rheumatic diseases.
H-D, Chang, T, Kamradt, H, Schulze-Koops
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Immunology Today, 1997
Abstract The Th1/Th2 paradigm provides a useful model for understanding the pathogenesis of several diseases, as well as for developing novel immunotherapeutic strategies. Here, Sergio Romagnani examines Th1/Th2 polarization in the context of associated pathophysiological conditions.
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Abstract The Th1/Th2 paradigm provides a useful model for understanding the pathogenesis of several diseases, as well as for developing novel immunotherapeutic strategies. Here, Sergio Romagnani examines Th1/Th2 polarization in the context of associated pathophysiological conditions.
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Springer Seminars in Immunopathology, 1999
Cytokines produced by T helper (Th) cells are of critical importance for the outcome of many infectious diseases. Producing the "right" set of cytokines in response to an infectious agent can be a matter of life or death. The Th1/Th2 dichotomy, although an oversimplification has proven useful in the analysis of immune responses to infections.
C, Infante-Duarte, T, Kamradt
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Cytokines produced by T helper (Th) cells are of critical importance for the outcome of many infectious diseases. Producing the "right" set of cytokines in response to an infectious agent can be a matter of life or death. The Th1/Th2 dichotomy, although an oversimplification has proven useful in the analysis of immune responses to infections.
C, Infante-Duarte, T, Kamradt
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Th1/Th2 balance in preeclampsia
Journal of Reproductive Immunology, 2003The syndrome of preeclampsia has previously been ascribed to generalized maternal endothelial dysfunction, poor placentation and excessive maternal inflammatory response. Recent reports suggest that preeclampsia is associated with a Th1 predominant profile and may be considered as a failure of the tolerance system allowing the second physiological ...
Shigeru, Saito, Masatoshi, Sakai
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