Results 51 to 60 of about 319,332 (247)
Identification of Sorafenib as a Treatment for Type 1 Diabetes
Frontiers in Immunology, 2022 Th1 cell activation is considered a key mediator of the pathogenesis of type 1 diabetes. Targeting IL-12-induced Th1 cell differentiation seems to be an effective way to block the development of type 1 diabetes.
Qin Zeng +18 more
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Th1 effector T cells selectively orchestrate cardiac fibrosis in nonischemic heart failure
Journal of Experimental Medicine, 2017 Despite emerging data indicating a role for T cells in profibrotic cardiac repair and healing after ischemia, little is known about whether T cells directly impact cardiac fibroblasts (CFBs) to promote cardiac fibrosis (CF) in nonischemic heart failure ...
T. Nevers +7 more
semanticscholar +1 more source
Indian Dermatology Online JournalBackground: The response of atopic dermatitis (AD) to different biologics and JAK inhibitors (JAKibs) is variable due to the varied immunological endotypes of AD.
Kabir Sardana +4 more
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Specific T cell induction using iron oxide based nanoparticles as subunit vaccine adjuvant
Human Vaccines & Immunotherapeutics, 2018 Metal-based nanoparticles (NPs) stimulate innate immunity; however, they have never been demonstrated to be capable of aiding the generation of specific cellular immune responses. Therefore, our objective was to evaluate whether iron oxide-based NPs have
Lázaro Moreira Marques Neto +7 more
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PATHOGENETIC ROLE OF CYTOKINES IN CHILDHOOD ROTAVIRUS INFECTION
Медицинская иммунология, 2014 . Results of cytokine network studies system in children with rotavirus infection are presented. Concentrations of cytokines were determined at both local and systemic levels.
S. N. Benyova +2 more
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Journal of Experimental Medicine, 2017 Type 1 T helper (Th1) cells play a critical role in host defense against intracellular pathogens and in autoimmune diseases by producing a key inflammatory cytokine interferon (IFN)–&ggr;; some Th1 cells can also be antiinflammatory through producing IL ...
Fang Yu +10 more
semanticscholar +1 more source
Pifu-xingbing zhenliaoxue zazhi[Objective] To study the therapeutic effects of Qinghuang ointment on psoriasis and its underlying mechanisms in a mouse model. [Methods] Twenty-five mice were randomly assigned to the following groups: blank control group, model group, Qinghuang ...
LIU Dan +6 more
doaj +1 more source
STAT1 expression controls CD4 T cell Th1 and Th17 effector functionality during influenza virus infection [PDF]
, 2023 Caroline Finn +3 more
openalex +1 more source
Annals of the New York Academy of Sciences, 2010 Autoreactive effector CD4+ T cells have been associated with the pathogenesis of autoimmune disorders. Early studies implicated the interferon (IFN)‐γ‐producing T helper (Th)1 subset of CD4+ cells as the causal agents in the pathogenesis of autoimmunity. However, further studies have suggested a more complex story. In models thought to be driven by Th1
Jesse M, Damsker +2 more
openaire +2 more sources
Subjectivity, historical imagination and the language of art history [PDF]
Journal of Art Historiography, 2020 Analysing the writings of Michael Baxandall, Michael Ann Holly, Adrian Stokes and T. J. Clark, and responding to recent art historiographical interest in the foregrounding of subjectivity, this essay deploys Baxandall’s analysis of the verbal description
Thomas Hughes
doaj