Results 61 to 70 of about 318,750 (310)

Evaluation of Th1 and TH2 Cytokine Network in Aspergilus Infected Tumor Bearing Mice [PDF]

Journal of Advanced Biomedical Sciences, 2012
Background & Objective: Invasive Aspergillosis is a fatal infection in immunocompromised patients. The aim of this study was to evaluate the interaction of infectious with Aspergillus and tumor on immune response and cytokine network in Aspergillus ...
Noushin Sohrabi, Majid Tebyanyan, Mehdi Mahdavi   +2 more
doaj  

Stable T-bet(+)GATA-3(+) Th1/Th2 hybrid cells arise in vivo, can develop directly from naive precursors, and limit immunopathologic inflammation. [PDF]

PLoS Biology, 2013
Differentiated T helper (Th) cell lineages are thought to emerge from alternative cell fate decisions. However, recent studies indicated that differentiated Th cells can adopt mixed phenotypes during secondary immunological challenges.
Michael Peine, Sebastian Rausch, Caroline Helmstetter, Anja Fröhlich, Ahmed N Hegazy, Anja A Kühl, Christoph G Grevelding, Thomas Höfer, Susanne Hartmann, Max Löhning   +9 more
doaj   +1 more source

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

Advanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He, Jielan Mi, Zhiping Zhao, Xiao Zhang, Zhihan Yang, Kun Yue, Yuanming Huang, Liqiong Song, Xiaoting Wen, Jianguo Xu, Zhihong Ren   +10 more
wiley   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Tyr-6 phosphorylation of TH1 impairs its inhibition on MAPK/ERK signaling.

, 2013
(A) TH1-Y6E mutant lost its inhibition on ERK phosphorylation. HeLa cells were transfected either with Myc-TH1-WT (wild type of TH1), with Myc-TH1-Y6E (the constitutive phosphorylation form of TH1), or with TH1-Y6F (the dephosphorylation form of TH1) and
Chunyi Zhang (335761), Jingwen Wu (80821), Haiyan Zhu (110483), Songwen Zhang (125578), Zhichao Sun (335759), Huacheng Gan (335760), Lingling Ji (335762), Jianxin Gu (335766), Shifang Ren (335763), Xiaomin Peng (296700), Weibin Wu (335758), Jianhui Xie (152717)   +11 more
core   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

Incidental Thoracic Th1 Spina Bifida Occulta Detection Following Sports Injury: A Case Report with Comprehensive Radiological Insights

Journal of Orthopaedic Case Reports
Introduction: Spina bifida is a neural tube defect and the incidence in the thoracic region is extremely rare. We reported an incidental finding of thoracic spina bifida occulta at the first thoracic vertebra following a sport-related injury. Case Report:
Sinan Kara, Amel Gorani, Bruno Baillon, Alexandre Grandjean, Thomas Von Waldburg, Tevi Morel Lawson   +5 more
doaj   +1 more source

Specific T cell induction using iron oxide based nanoparticles as subunit vaccine adjuvant

Human Vaccines & Immunotherapeutics, 2018
Metal-based nanoparticles (NPs) stimulate innate immunity; however, they have never been demonstrated to be capable of aiding the generation of specific cellular immune responses. Therefore, our objective was to evaluate whether iron oxide-based NPs have
Lázaro Moreira Marques Neto, Nicholas Zufelato, Ailton Antônio de Sousa-Júnior, Monalisa Martins Trentini, Adeliane Castro da Costa, Andris Figueiroa Bakuzis, André Kipnis, Ana Paula Junqueira-Kipnis   +7 more
doaj   +1 more source

CXCR3 LIGANDS CONTRIBUTE TO Th1-INDUCED INFLAMMATION BUT NOT TO HOMING OF Th1 CELLS INTO THE LUNG [PDF]

Experimental Lung Research, 2008
Th1 cells are implicated in numerous pulmonary inflammatory disorders, and adoptive transfer of alloreactive Th1 cells mediates lung injury and inflammation in mice. In response to Th1-mediated immune injury, CXCR3 ligands IP10 and MIG are markedly induced. Because Th1 cells express high levels of CXCR3, their recruitment and activity may be influenced
Anne M, Manicone, Kristi M, Burkhart, Bao, Lu, Joan G, Clark   +3 more
openaire   +2 more sources

Phosphorylation of TH1 by c-Src.

, 2013
(A) c-Src phosphorylates TH1. COS-7 cells transfected as indicated were lysed, precipitated with anti-Myc antibody bound agarose beads, followed by western blot with anti-phosphotyrosine (4G10) and anti-Myc antibodies. (B) Tyrosine phosphorylation of TH1
Chunyi Zhang (335761), Jingwen Wu (80821), Haiyan Zhu (110483), Songwen Zhang (125578), Zhichao Sun (335759), Huacheng Gan (335760), Lingling Ji (335762), Jianxin Gu (335766), Shifang Ren (335763), Xiaomin Peng (296700), Weibin Wu (335758), Jianhui Xie (152717)   +11 more
core   +1 more source