Results 61 to 70 of about 104,301 (246)

Engineering Immunoregenerative Therapy via an Immunomodulatory Binary Pharmacology Hydrogel Depot for Prolonged Allograft Survival

Advanced Science, EarlyView.
An immunomodulatory hydrogel (iGEL) forms spontaneously upon subcutaneous injection, acting as a tissue‐adhesive depot. It releases anti‐rejection and regenerative agents in response to inflammation, suppressing T‐cell activity, promoting vascular repair, and restoring allograft function without systemic immunosuppression.
Ning Wang, Ruiqi Sun, Yang Fu, Zhonghan Wu, Xinyu Tong, Hong Tang, Wentao Zhao, Zhi Liang, Jintao Zheng, Yanan Guan, Ke Zhou, Penghong Song, Shusen Zheng, Hangxiang Wang, Haiyang Xie   +14 more
wiley   +1 more source

Study on the therapeutic effects of Qinghuang ointment in a mouse model of imiquimod-induced psoriasis and its underlying mechanisms

Pifu-xingbing zhenliaoxue zazhi
[Objective] To study the therapeutic effects of Qinghuang ointment on psoriasis and its underlying mechanisms in a mouse model. [Methods] Twenty-five mice were randomly assigned to the following groups: blank control group, model group, Qinghuang ...
LIU Dan, GONG Canyi, XU Jing, WEN Si, WU Zhaoji, HE Jiao, XIA Bijun   +6 more
doaj   +1 more source

Th1/Th2 paradigm: not seeing the forest for the trees? [PDF]

European Respiratory Journal, 2005
In this issue of the European Respiratory Journal , Irifune et al. 1 describe the effects of adoptive transfer of T-helper cell type 1 (Th1) cells in a mouse asthma model. Since the 1980s, the Th1/Th2 dichotomy has been considered the cornerstone of immune responses 2.
van Oosterhout, AJM, Motta, AC
openaire   +2 more sources

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

TH1-313

, 2016
A rough Fataluku translation of portions of the biblical book Mark 4Lautem district, East ...

core   +1 more source

Neoadjuvant sipuleucel-T induces both Th1 activation and immune regulation in localized prostate cancer

OncoImmunology, 2019
Sipuleucel-T is the only FDA-approved immunotherapy for metastatic castration-resistant prostate cancer. The mechanism by which this treatment improves survival is not fully understood.
Katsunobu Hagihara, Stephen Chan, Li Zhang, David Y. Oh, Xiao X. Wei, Jeffry Simko, Lawrence Fong   +6 more
doaj   +1 more source

Subjectivity, historical imagination and the language of art history [PDF]

Journal of Art Historiography, 2020
Analysing the writings of Michael Baxandall, Michael Ann Holly, Adrian Stokes and T. J. Clark, and responding to recent art historiographical interest in the foregrounding of subjectivity, this essay deploys Baxandall’s analysis of the verbal description
Thomas Hughes
doaj  

Radiotherapy Enhances the Oncolytic Efficacy of the Novel Oncolytic Herpesvirus VG161 and Amplifies Its Antitumor Immunity in Breast Cancer

Advanced Science, EarlyView.
RT promotes VG161 replication in BC and its immunostimulatory transgenes expression, which is mediated by the upregulation of GADD34 and HVEM caused by RT. The combination therapy with VG161 and RT increases the abundances of tumor‐infiltrating lymphocytes and elicits potent systemic antitumor immunity, thereby effectively inhibiting local tumors and ...
Lijuan Lyu, Ming Yi, Ji Chen, Zeda Zhao, Ruocen Liao, Yingnan Wang, Shengtao Hu, Jun Ding, Ronghua Zhao, William Jia, Yinan Shen, Yongchang Wei, Kongming Wu, Zhijun Dai   +13 more
wiley   +1 more source

Erythromycin Prevents Elastin Peptide-Induced Emphysema and Modulates CD4+T Cell Responses in Mice

International Journal of COPD, 2019
Shudan Tang,* Tingting Ma,* Hui Zhang,* Jianquan Zhang, Xiaoning Zhong, Caimei Tan, Ye Qiu, Wen Zeng, Xin Feng Department of Respiratory Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, People’s ...
Tang S, Ma T, Zhang H, Zhang J, Zhong X, Tan C, Qiu Y, Zeng W, Feng X   +8 more
doaj  

Common Features of Regulatory T Cell Specialization During Th1 Responses

Frontiers in Immunology, 2018
CD4+Foxp3+ Treg cells are essential for maintaining self-tolerance and preventing excessive immune responses. In the context of Th1 immune responses, co-expression of the Th1 transcription factor T-bet with Foxp3 is essential for Treg cells to control ...
Katharina Littringer, Claudia Moresi, Nikolas Rakebrandt, Xiaobei Zhou, Xiaobei Zhou, Michelle Schorer, Tamas Dolowschiak, Florian Kirchner, Felix Rost, Christian W. Keller, Donal McHugh, Salomé LeibundGut-Landmann, Mark D. Robinson, Mark D. Robinson, Nicole Joller   +14 more
doaj   +1 more source