Results 81 to 90 of about 451,440 (299)
Topological Point Defects in SmC* Liquid Crystals Under Mechanical Disturbance
Advanced Materials Interfaces, EarlyView.Tangetial air jet shear inducess island formation and nucleates topological point defects in uniform SmC films. Island bounded by edge dislocation loops shrink and transform into isolated point defects under continued shear. Mechanical perturbatio provides a controllable route for defect engineering in smectric liquid crystal thin films.
Gunganist Kongklad +3 more
wiley +1 more source
OncoImmunology, 2019 Sipuleucel-T is the only FDA-approved immunotherapy for metastatic castration-resistant prostate cancer. The mechanism by which this treatment improves survival is not fully understood.
Katsunobu Hagihara +6 more
doaj +1 more source
Subjectivity, historical imagination and the language of art history [PDF]
Journal of Art Historiography, 2020 Analysing the writings of Michael Baxandall, Michael Ann Holly, Adrian Stokes and T. J. Clark, and responding to recent art historiographical interest in the foregrounding of subjectivity, this essay deploys Baxandall’s analysis of the verbal description
Thomas Hughes
doaj
Theta Bodies for Polynomial Ideals
, 2009 Inspired by a question of Lov\'asz, we introduce a hierarchy of nested semidefinite relaxations of the convex hull of real solutions to an arbitrary polynomial ideal, called theta bodies of the ideal.
Gouveia, João +2 more
core +3 more sources
PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC
Advanced Science, EarlyView.CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao +16 more
wiley +1 more source
Common Features of Regulatory T Cell Specialization During Th1 Responses
Frontiers in Immunology, 2018 CD4+Foxp3+ Treg cells are essential for maintaining self-tolerance and preventing excessive immune responses. In the context of Th1 immune responses, co-expression of the Th1 transcription factor T-bet with Foxp3 is essential for Treg cells to control ...
Katharina Littringer +14 more
doaj +1 more source
Twisted Blanchfield pairings and symmetric chain complexes [PDF]
, 2016 We define the twisted Blanchfield pairing of a symmetric triad of chain complexes over a group ring Z[G], together with a unitary representation of G over an Ore domain with involution. We prove that the pairing is sesquilinear, and we prove that it is
Powell, Mark
core +2 more sources
RETREG1‐Mediated Reticulophagy is Essential for Dendritic Cell Maturation and Function in Sepsis
Advanced Science, EarlyView.Reticulophagy regulator 1 (RETREG1) maintains dendritic cell (DC) maturation and function in early sepsis. Mechanistically, activating transcription factor 6 (ATF6) acts as a direct transcription factor regulating RETREG1 expression in response to sepsis‐induced endoplasmic reticulum (ER) stress.
Ren‐Qi Yao +28 more
wiley +1 more source
Erythromycin Prevents Elastin Peptide-Induced Emphysema and Modulates CD4+T Cell Responses in Mice
International Journal of COPD, 2019 Shudan Tang,* Tingting Ma,* Hui Zhang,* Jianquan Zhang, Xiaoning Zhong, Caimei Tan, Ye Qiu, Wen Zeng, Xin Feng Department of Respiratory Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, People’s ...
Tang S +8 more
doaj
A mucin-like peptide from Fasciola hepatica instructs dendritic cells with parasite specific Th1-polarizing activity [PDF]
, 2017 Fasciolosis is a trematode zoonosis of interest in public health and cattle production. We report here the immunostimulatory effect of a 66 mer mucin-like peptide from Fasciola hepatica (Fhmuc), which synergizes with lipopolysaccharide (LPS) to promote ...
Brossard, Natalie +6 more
core +1 more source