Results 51 to 60 of about 318,750 (310)

Resting respiratory tract dendritic cells preferentially stimulate T helper cell Type 2(Th2) responses and require obligatory cytokine signals for induction of Th1 immunity [PDF]

, 1998
Consistent with their role in host defense, mature dendritic cells (DCs) from central lymphoid organs preferentially prime for T helper cell type 1 (Th1)-polarized immunity.
Venaille, T.J., Lee, P.T., Stumbles, P.A., Pimm, C.L., Proksch, S., Holt, P.G., Thomas, J.A.   +6 more
core  

Th1-culture supernatants and TNF-α upregulate CD106 expression on SFbs.

, 2016
SFbs from healthy donors were cultured for 48h in presence of medium alone (CTRL) or cultured supernatants of unstimulated (dark grey) or anti-CD3/CD28 stimulated (light grey) Th cells clones of different phenotypes (classic and non-classic Th1 and Th17)
Veronica Santarlasci (2635498), Laura Maggi (2635513), Maria Caterina Rossi (2635519), Francesco Liotta (323868), Francesca Margheri (296258), Enrico Maggi (724843), Lorenzo Cosmi (2635504), Cristina Luciani (2635510), Francesco Annunziato (2635501), Rolando Cimaz (459122), Anastasia Chillà (296269), Alessio Mazzoni (2635507), Manuela Capone (2635516), Mario Del Rosso (296279)   +13 more
core   +1 more source

Poisson's Ratio‐Driven Control of Myogenic Differentiation and Maturation in Auxetic Metamaterials under Dynamic Mechanical Stimulation

Advanced Functional Materials, EarlyView.
This study explored how innovative “auxetic” scaffolds, which expand when stretched, influence skeletal muscle development. Researchers cultured muscle cells on different scaffold designs and applied repeated stretching over 10 days. They found that scaffold geometry affected muscle cell differentiation and fiber formation.
Maria Kalogeropoulou, Prabhdeep Kaur, Monica Boffito, Pierpaolo Fucile, Gianluca Ciardelli, Lorenzo Moroni   +5 more
wiley   +1 more source

Th1 and Th2 profile.

, 2019
Th1 profile in SL transfected with negative control (scrambled), miR 21 mimic, miR 21 inhibitor and cultured for 67h. (A) SL from dogs with CanL and (B) SL from control non-infected dogs.
Gabriela Torres Rebech (6053297), Valéria Marçal Felix de Lima (8115269), Sidnei Ferro Costa (8115260), Flávia Lombardi Lopes (6058841), Paulo Sérgio Patto dos Santos (8115266), Leandro Encarnação Garcia (5488019), Larissa Martins Melo (5488028), Jaqueline Poleto Bragato (5488034), Flávia de Rezende Eugênio (8115263), Gabriela Lovizutto Venturin (6053294)   +9 more
core   +1 more source

related Th1 and Th2 cytokines mRNA levels.pzf

, 2022
related Th1 and Th2 cytokines mRNA ...
Siran Tan (11971310)
core   +1 more source

Bacteria‐Trained, MnO2‐Armored Dendritic Cells for Immunotherapy

Advanced Materials, EarlyView.
MnO2‐armored, bacteria‐trained dendritic cells undergo tumor‐responsive mechanical and immunological transformation. The nanocoating masks immune ligands and maintains a mechanically stiff, quiescent state during circulation, while the tumor microenvironment removes the armor and restores cellular deformability and immune accessibility.
Zhao Guo, Min Ge, Zesong Ruan, Tingwang Shi, Mahyar Mahmoudi, Soohwan An, Na Kong, Yunfeng Chen, Han Lin, Wei Tao   +9 more
wiley   +1 more source

Immune response to inactivated bacterial vector carrying the recombinant K39 antigen of Leishmania infantum in mice

Asian Pacific Journal of Tropical Biomedicine
Objective: To evaluate the immunological response elicited by an inactivated bacterial vector carrying the K39 antigen of Leishmania infantum, and a purified antigen. Methods: Mice were subjected to the following treatments: (1) Purified recombinant K39 (
Araújo Lucelina S., Silva Bruno B., Santos Eduarda N. F. N., Bezerra Arnaldo S., Frota Samuel S., Montenegro Assis R., Florean Eridan O. P. T., van Tilburg Maurício F., Guedes Maria Izabel F.   +8 more
doaj   +1 more source

The significance of Th1,Th2,Th17and treg cells in the prediction and evaluation of ulcerative colitis

European Journal of Inflammation, 2023
Objective This study aimed to investigate clinical significance of Th1, Th2, Th17 and Tregs proportions in predicting and evaluating UC. Methods A total of 101 UC patients diagnosed by the Department of Gastroenterology of the Shanxi Provincial People’s ...
Yu Zhang, Wei Shi, Gaigai Cao, Jingru Li, Haijiao Wang, Chonghua Hao   +5 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Glutaminase 1-mediated glutaminolysis regulates tuberculosis progression by modulating Th1 and Th17 immune responses

Central European Journal of Immunology
Introduction Mycobacterium tuberculosis-mediated tuberculosis (TB) is an infectious disease that results in approximately 1.2 million deaths annually. Glutaminase (GLS1) is a metabolic enzyme involved in glutaminolysis.
Xiaozhen Cai, Yidan Huang, Lili Zeng, Rong Rong   +3 more
doaj   +1 more source