Results 41 to 50 of about 318,750 (310)
as Th1 stimulatory, in experimental visceral leishmaniasis
, 2015 In earlier studies, proteomic characterization of splenic amastigote fractions from clinical isolates of Leishmania donovani, exhibiting significant cellular responses in cured Leishmania subjects, led to the identification of cytosolic tryparedoxin ...
ANIL KUMAR JAISWAL +13 more
core +1 more source
Global Rather Than Vertical‐Selective Saccadic Abnormalities in Progressive Supranuclear Palsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To test whether vertical saccades are preferentially affected in Progressive Supranuclear Palsy (PSP). Methods PSP patients (n = 24) were compared to age‐matched controls (n = 94) and two degenerative groups (Alzheimer's disease, n = 20; Lewy body disease, n = 50).
Duy Duan Nguyen +6 more
wiley +1 more source
Enhanced cell migration through Tyr-6 phosphorylation of TH1.
, 2013 (A) TH1-WT inhibits HeLa cell migration. HeLa cells were transfected with Myc-TH1-WT or control vector. Transwell cell migration assay was performed as described under “Experimental Procedures” (n = 4, mean ± SD ...
Chunyi Zhang (335761) +11 more
core +1 more source
Epicutaneous immunization with type II collagen inhibits both onset and progression of chronic collagen-induced arthritis. [PDF]
, 2007 Epicutaneous immunization is a potential non-invasive technique for antigen-specific immune-modulation. Topical application of protein antigens to barrier-disrupted skin induces potent antigen-specific immunity with a strong Th2-bias.
Strobel, S +9 more
core +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno +19 more
wiley +1 more source
Frontiers in Microbiology, 2022 AimsMicroRNA-451a (miR-451a) regulates Th1/Th2 cell differentiation, inflammation, and septic organ injury in several experiments. Therefore, the present study aimed to explore the inter-correlation of miR-451a with the Th1/Th2 ratio, and their ...
Feng Geng, Wei Liu, Li Yu
doaj +1 more source
Interaction of c-Src with TH1.
, 2013 (A) c-Src interacts with TH1. HEK293T cells were transiently transfected with GFP-TH1 and/or HA-c-Src as described under “Experimental Procedures”. At 36 h after transfection, the cells were lysed, immunoprecipitated (IP) with 2 µg of anti-GFP antibody ...
Chunyi Zhang (335761) +11 more
core +1 more source
IFN-γ and TNF-α synergize to inhibit CTGF expression in human lung endothelial cells. [PDF]
, 2012 Connective tissue growth factor (CTGF/CCN2) is an angiogenetic and profibrotic factor, acting downstream of TGF-β, involved in both airway- and vascular remodeling.
Steffen Kunzmann +21 more
core +2 more sources
A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions
Advanced Engineering Materials, EarlyView.This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice +2 more
wiley +1 more source
Further Checkpoints in Th1 Development [PDF]
Immunity, 2002 Tight control of Th1 immunity is essential to prevent immunopathology. Central to control of the IFN-gamma gene is the transcription factor T-bet, whose induction is Stat-1 dependent. IL-12 is dominant in directing Th1 development, while synergizing with IL-18 for IFNgamma production from differentiated Th1 cells.
Robinson, Douglas S, O'Garra, Anne
openaire +2 more sources