Results 111 to 120 of about 185,105 (239)

Alleviating Effects of Citrus Polymethoxyflavones on Autoimmune Thyroiditis via IL‐17 Signaling Pathway

open access: yesFood Frontiers, EarlyView.
Citrus flavonoid extracts reduced TPO‐ Ab levels in AITDs cell models. PMFs exhibited the strongest effect on alleviating AITDs among citrus flavonoids. Tangeretin modulated IL‐ 17 signaling pathway to prevent AITDs, and reduced NaI‐ induced thyroid damage in AITDs mouse model.
Manxi Wu   +11 more
wiley   +1 more source

Exploring the bio‐functional potential of polysaccharides from Morchella esculenta: A mini review

open access: yesFood Biomacromolecules, EarlyView.
Abstract Polysaccharides, natural polymers of monosaccharides, exhibit diverse biological activities due to their molecular structures and functional properties. Morchella esculenta, a precious edible mushroom with higher market value, is also rich in polysaccharides (MEP) and holds potential as a bioactive compound with therapeutic and functional food
Shiva Bakshi, Vinod Kumar Paswan
wiley   +1 more source

Dry Eye Disease: Oxidative Stress on Ocular Surface and Cutting‐Edge Antioxidants

open access: yesGlobal Challenges, EarlyView.
This review has systematically evaluated the oxidative damage of cornea, tear film, lacrimal gland, conjunctiva and meibomian gland for dry eye, and concluded the antioxidants that are either commercially available or in the research phase. GQDs: Graphene quantum dots; LF: lactoferrin; ROS: Reactive oxygen species; SOD: Superoxide dismutase; tFNA ...
Rong Hu   +3 more
wiley   +1 more source

Pathways to Progressive Disability in Multiple Sclerosis: The Role of Glial Cells in Chronic CNS Inflammation

open access: yesGlia, EarlyView.
ABSTRACT Multiple sclerosis (MS) is the most common non‐infectious inflammatory CNS disease, characterized by progressive neurodegeneration and focal demyelinated lesions. Traditionally considered an autoimmune disease, MS is driven by the immune system's attack on CNS myelin, resulting in cumulative disability.
Volker Siffrin
wiley   +1 more source

Malignant Pleural Effusion: Palliative Managements and Indication for Pleurodesis Based on Survival Scores

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT Neoplastic pleural effusion is one in which malignant neoplastic cells are detected in the pleural fluid or in the parietal pleura. When secondary, it confirms disseminated neoplastic disease and suggests a reduced life expectancy and low quality of life.
Erlon de Avila Carvalho   +9 more
wiley   +1 more source

Breaking Boundaries: Chronic Diseases and the Frontiers of Immune Microenvironments

open access: yesMed Research, EarlyView.
ABSTRACT The immune microenvironment includes immune cells, cytokines, extracellular matrix, vesicles, etc. The interactions between these components form a unique local immune microecology. Although immunity serves as the defense against external pathogens, aberrant immune activation often contributes to disease development.
Guoqing Li   +13 more
wiley   +1 more source

Virus-friendly Th17s [PDF]

open access: yesJournal of Experimental Medicine, 2009
openaire   +2 more sources

Peripheral Mononuclear Cell Mitochondrial Function Associates with T‐Cell Cytokines in Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Parkinson's disease (PD) is the most common neurodegenerative movement disorder and one of the world's fastest‐growing neurological diseases. Although the exact causes of PD are unknown, mitochondrial dysfunction and inflammation may have significant roles in disease progression.
Fatima Afaar   +6 more
wiley   +1 more source

The role of gut microbiota‐derived metabolites in neuroinflammation

open access: yesNeuroprotection, EarlyView.
Gut microbiota‐derived metabolites accumulate in the brain, activating or inhibiting microglia and astrocytes, which affects neuroinflammatory progression. The gut microbiota converts the diet into a variety of metabolites, including bile acid, trimethylamine N‑oxide (TMAO), and indole.
Lingjie Mu, Yijie Wang
wiley   +1 more source

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