Results 91 to 100 of about 163,225 (299)

Acquisition of pneumococci specific effector and regulatory Cd4+ T cells localising within human upper respiratory-tract mucosal lymphoid tissue [PDF]

, 2011
The upper respiratory tract mucosa is the location for commensal Streptococcus (S.) pneumoniae colonization and therefore represents a major site of contact between host and bacteria.
Mitchell, T.J., Pido-Lopez Jeffrey, Pido-Lopez, J., Mitchell, TJ, Williams Neil A., Kwok, William W, Robert S. Heyderman, Neil A. Williams, Mitchell, Timothy J, Heyderman Robert S., Robert S Heyderman, Williams, NA, Pido, J, Neil A Williams, Mitchell Timothy J., Timothy J. Mitchell, Timothy J Mitchell, Heyderman, R.S., Pido-Lopez, Jeffrey, Kwok, W, Kwok William W., Williams, N.A., Heyderman, RS, William W Kwok, Jeffrey Pido-Lopez, Williams, Neil A, Kwok, W.W., William W. Kwok, Heyderman, Robert S   +28 more
core   +1 more source

Th1, Th2, and Th17 cytokines in systemic lupus erythematosus

Autoimmunity, 2020
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the breakdown of immune tolerance leading to excessive inflammation and tissue damage.
Farhana Muhammad Yusoff, Kah Keng Wong, Norhanani Mohd Redzwan   +2 more
doaj   +1 more source

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

Advanced Science, EarlyView.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori, Ahmed Shaney Rehman, Taruna Lamba, Anas Ahmad, Jattin Kumar, Aneesh Ali, Ajesh Joshi, Ashraf Ali, Suhel Parvez, Javed N. Agrewala, Rehan Khan   +10 more
wiley   +1 more source

CD69 Association with Jak3/Stat5 Proteins Regulates Th17 Cell Differentiation

, 2010
This work was supported by grant SAF2008-02719 from the Spanish Ministry of Science and Innovation to P.M.; grant PI06/0937 from ISCIII-MSC to M.G.; and grants SAF2008-02635 from the Spanish Ministry of Science and Innovation, RECAVA [RD06/0014-0030 ...
Martín, Pilar, María Yáñez-Mo, Ramírez-Huesca, Marta, Arantxa Cruz-Adalia, Marta Ramírez-Huesca, Pilar Martín, Manuel Gómez, María Ángeles Ursa, Ursa, María Ángeles, Gómez, Manuel, Lamana Domínguez, Amalia, Francisco Sánchez-Madrid, Yáñez-Mo, María, Sánchez-Madrid, Francisco, Cruz Adalia, Aranzazu, Amalia Lamana   +15 more
core   +1 more source

Histopathologic and immunological features of Imiquimod induced psoriatic mouse model

Pifu-xingbing zhenliaoxue zazhi, 2019
Objective: To investigate the dermatopathologic and immunological features of Imiquimod induced psoriatic mice model. Methods: Twenty BALB/c mice were grouped in IMQ-model group and control group randomly, each had 10 mice.
Zhong-zhou HUANG, Xiao-yan CHEN, Min XU, Xue-chen AI, Zeng-qi TANG, Qing GUO   +5 more
doaj   +1 more source

Probiotic‐Derived Vesicles Rectally Delivered via Thermo‐Gelling Copolymer Promote Mucosal Healing and Reduce Inflammation in Ulcerative Colitis

Advanced Science, EarlyView.
A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal, Ubaid Tariq, Shreya Mehrotra, Saravanan Matheshwaran, Jan Marsal, Ashok Kumar   +5 more
wiley   +1 more source

Th17 cells: inflammation and regulation [PDF]

, 2014
IL-17-producing CD4+ T cells (Th17 cells) are understood to be a distinct lineage of CD4+ T helper (Th) cells, which play an important role in the host defense, tissue inflammation and autoimmunity.
Kishimoto, T, Masuda, K
core   +1 more source

Engineering‐Modulated Molybdenum Enzymes Strategy for Tumor‐Specific Metabolic‐Immunotherapy

Advanced Science, EarlyView.
Biodegradable molybdenum sulfide nanoparticles were synthesized via a one‐pot strategy to increase molybdenum enzyme activity and thus effectively potentiate anti‐tumor immunity by integrating molybdenum‐based metalloimmunotherapy with hydrogen sulfide gas therapy.
Xiaoxiao Pan, Zifan Pei, Jie Wu, Nan Jiang, Qian Li, Yuqi Yang, Jie Cao, Yechen Huang, Shumin Sun, Qialu Du, Zhicheng Liu, Lin Zhang, Fei Gong, Jinhua Zhou, Liang Cheng   +14 more
wiley   +1 more source

Gallic Acid Ameliorates Atopic Dermatitis-Like Skin Inflammation Through Immune Regulation in a Mouse Model

Clinical, Cosmetic and Investigational Dermatology, 2021
Guohong Hu, Xiansheng Zhou Dermatology Hospital of Jiangxi Province, Nanchang, 330001, Jiangxi, People’s Republic of ChinaCorrespondence: Guohong HuDermatology Hospital of Jiangxi Province, No.
Hu G, Zhou X
doaj  

TH17 deficiency in human disease [PDF]

Journal of Allergy and Clinical Immunology, 2012
The differentiation of naive T cells into distinct subsets of effector T cells is critical for effective immunity against a wide variety of infectious agents in the environment. Activation of innate immune responses by Candida species through pattern-recognition receptors directs the subsequent development of naive T cells into T(H)17 cells, which are ...
openaire   +2 more sources