The insufficient sensitivity of single circulating tumor DNA (ctDNA)‐molecular residual disease (MRD) prediction remains unresolved and hinders the clinical implementation of ctDNA. Through prospective cohort study, independent validations, and mechanism exploration from peripheral blood and tumor tissue, we demonstrate that ctDNA‐based STK11/KEAP1 ...
Yu Wang+10 more
wiley +1 more source
GPR55 Antagonist CID16020046 Suppresses Collagen-Induced Rheumatoid Arthritis by Suppressing Th1/Th17 Cells in Mice. [PDF]
Lee JE, Im DS.
europepmc +1 more source
The Fos-related antigen 1–JUNB/activator protein 1 transcription complex, a downstream target of signal transducer and activator of transcription 3, induces T helper 17 differentiation and promotes experimental autoimmune arthritis [PDF]
et al,, Kim, Woo Kyung
core +1 more source
Deciphering the panvascular immune landscape of atherosclerosis
Atherosclerosis (AS) involves inflammation in major arteries and can cause severe cardiovascular events like heart attacks and strokes, yet disease patterns vary significantly between arteries, complicating diagnosis and treatment. In this study, we integrated transcriptomic and single‐cell RNA sequencing data from AS plaques across five key arterial ...
Yiming Zhong+12 more
wiley +1 more source
Independent and temporally separated dynamics for RORγt and Foxp3 during Th17 differentiation. [PDF]
Miller S+8 more
europepmc +1 more source
The nuclear receptor REV-ERBα modulates Th17 cell-mediated autoimmune disease [PDF]
Atkins, Annette R.+14 more
core +1 more source
ABSTRACT Background Acute diffuse and total alopecia (ADTA) is a variant of alopecia areata (AA) that lacks the typical patchy hair loss seen in classical AA and presents with an acute onset of diffuse hair loss. It has a favorable prognosis. Objectives The purpose of this study was to assess the role of T‐helper (Th) 17 cells and regulatory T cells ...
Ji‐Hoon Lim+4 more
wiley +1 more source
Crosstalk with infant-derived Th17 cells, as well as exposure to IL-22 promotes maturation of intestinal epithelial cells in an enteroid model. [PDF]
Sharafian Z+10 more
europepmc +1 more source
NETosis: A bridge between cancer and autoimmunity
Rheumatology &Autoimmunity, EarlyView.
Niloufar Orooji, Manouchehr Fadaee
wiley +1 more source