Results 211 to 220 of about 169,698 (304)

Successful Co‐Administration of Secukinumab and Dupilumab in a Patient With Psoriasis and Paradoxical Atopic Dermatitis

JEADV Clinical Practice, EarlyView.
ABSTRACT Paradoxical atopic dermatitis (AD) can arise during biologic therapy for psoriasis due to an immune‐axis imbalance. We describe a 47‐year‐old man who developed severe AD while receiving secukinumab, which was successfully managed with the addition of dupilumab, allowing long‐term control of both diseases.
So Yun Park, Minjung Park, Ho Eun Gwang, Narang Hong, Hye Jung Jung, Mi Youn Park, Jiyoung Ahn   +6 more
wiley   +1 more source

Paradoxical Alopecia Areata Induced by IL‐17 and IL‐23 Inhibitors: A Systematic Review

JEADV Clinical Practice, EarlyView.
This systematic review identifies consistent clinical patterns of alopecia areata associated with IL‐17 and IL‐23 inhibitors, most frequently involving secukinumab and ustekinumab. Disease severity varied widely, and management often required biologic discontinuation or therapeutic switching.
Isabella Kamholtz, Simonetta I. Gaumond, Joaquin J. Jimenez   +2 more
wiley   +1 more source

Targeting the Th17/Treg axis: from immunological insights to therapeutic avenues in atherosclerosis. [PDF]

Front Immunol
Qin Z, Chen S, Lyu Z, Zhou F, Liu L, Ai Q, Zeng Z.   +6 more
europepmc   +1 more source

Nail Lichen Planus in Children ‐ Epidemiology, Pathogenesis, Clinical Presentation, and Treatment

JEADV Clinical Practice, EarlyView.
ABSTRACT Nail lichen planus (NLP) is a chronic inflammatory disorder that, while rare in children compared to adults, represents a significant cause of pediatric nail dystrophy that requires early recognition to prevent permanent scarring and nail loss.
Francesca Pampaloni, Matilde Iorizzo
wiley   +1 more source

<i>Staphylococcus aureus</i>-derived xanthine exacerbates allergic rhinitis-induced olfactory dysfunction through promoting Th17 cell differentiation and IL-17A production. [PDF]

Clin Transl Immunology
Hu Y, Wang W, Yang T, Song X, Wang Y, Cheng Y, Mou Y, Ren C, Song X.   +8 more
europepmc   +1 more source

The Effects of Biologic Agents on Carotid Intima‐Media Thickness and Hepatic Steatosis in Patients With Moderate‐To‐Severe Psoriasis: A Prospective Observational Cohort Study

JEADV Clinical Practice, EarlyView.
In this prospective observational cohort study, 34 patients with moderate‐to‐severe psoriasis received biologic therapy (anti‐TNF‐α, anti‐IL‐12/23, or anti‐IL‐17) for 6 months. Carotid intima–media thickness decreased significantly in the overall cohort (p < 0.01), with the greatest reductions in the anti‐IL‐17 and anti‐IL‐12/23 groups.
Harika Ödemiş, Burçe Can Kuru, Bilal Doğan, Ceyda Civan Kuş, Mehmethan Çelik, Nurhilal Kızıltoprak, Fatih Özçelik   +6 more
wiley   +1 more source

CD4⁺ T cell subset imbalance contributes to diabetic kidney disease progression: immunopathological mechanisms and targeted therapeutic strategies. [PDF]

Front Immunol
Zheng D, Zhang L, Li H, Wang D, Jiao C, Li X, Fu S.   +6 more
europepmc   +1 more source

Impact of BMI and Body Weight on Clinical Outcomes in Psoriasis: A Post Hoc Analysis of the RESOLVE Observational Study

JEADV Clinical Practice, EarlyView.
This post‐hoc analysis of the Greek real‐world ReSOLVE study compared clinical and patient‐reported outcomes by body weight (< 100 kg vs. ≥ 100 kg) and BMI over 52 weeks. Patients ≥ 100 kg showed delayed PASI and sPGA responses at W24 and W52, while BMI had little impact. Quality‐of‐life improvements were substantial, though early gains were smaller in
Pantelis Panagakis, Kanella Kalapothakou, Despina Exadactylou, Ioanna Lefaki, Marina Papoutsaki, Natalia Rompoti, Dimitrios Xekardakis, Nikolaos Fekkas, Efthymios Stathatos, Athanasios Chaniotis, Electra Nicolaidou, Alexandros Stratigos, Vasiliki Chasapi   +12 more
wiley   +1 more source

Subcorneal Pustular Dermatosis, a Systematic Review and Pooled Analysis of a Rare and Underdiagnosed Disease

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Subcorneal pustular dermatosis (SPD), or Sneddon–Wilkinson disease, is a rare, relapsing pustular skin condition of unknown cause, characterised by subcorneal pustules. Objectives To summarise the demographic, clinical, histopathological, management and disease course of SPD.
Mason H. Crossman, Jeffrey Weng, Alysha Vuong, Lawrence Lin, Zhao Feng Liu, Christopher Y. Chew   +5 more
wiley   +1 more source