Results 221 to 230 of about 187,124 (359)

Lactobacillus rhamnosus attenuates bone loss and maintains bone health by skewing Tregs-Th17 cell balance in Ovx mice [PDF]

, 2020
Leena Sapra, Hamid Y. Dar, Amit Kumar Pandey, Surbhi Kumari, Zaffar Azam, Asha Bhardwaj, Prashant Kumar Shukla, Pradyumna Kumar Mishra, Bhupendra Verma, Rupesh K. Srivastava   +9 more
openalex   +1 more source

Substrate Characterization of Mycobacterial Kinase PknG Revealing PknG‐KARS‐MAPK Phosphorylation Signaling Axis in Host

iMetaMed, EarlyView.
This study employed multi‐omics approaches to investigate the regulatory mechanism of Mycobacterium PknG on host cell processes. We found that host lysine‐tRNA ligase (KARS) is a potential substrate of PknG; and PknG can regulate the immune response by catalyzing the phosphorylation of KARS at T592 and T595 sites, affecting the phosphorylation level in
Nana Tian, Shuyu Xie, Yanqing Tang, Junjie Liang, Wenhan Zhu, Tianqi Liu, Yewen Sun, Yang Yang, Luoxi Zhang, Danfeng Wang, Chuyao Lin, Jinyu Jia, Minjia Tan, Jun‐Yu Xu   +13 more
wiley   +1 more source

TNF Pathway-Mediated Tolerogenic T-Cell Trajectory Driven by Allergen Immunotherapy. [PDF]

Allergy
Charles HS, Gabr AA, Wang SH, Zissler UM, Heine S, Heldner A, Kotz S, Pechtold L, Bonsen LSZ, Pogorelov D, Kau J, Plaschke M, Hills M, Guerth F, Oelsner M, Ohnmacht C, Alessandrini F, Blank S, Chaker AM, Schmidt-Weber CB, Jakwerth CA.   +20 more
europepmc   +1 more source

Bidirectional Cross-Talk between Biliary Epithelium and Th17 Cells Promotes Local Th17 Expansion and Bile Duct Proliferation in Biliary Liver Diseases [PDF]

, 2019
Hannah C. Jeffery, Stuart Hunter, E Humphreys, Ricky H. Bhogal, Rebecca E. Wawman, Jane Birtwistle, Muhammad Atif, Christopher J. Bagnal, Giovanny Rodriguez Blanco, Naomi Richardson, Suz Warner, Warwick B. Dunn, Simon C. Afford, David Adams, Ye Htun Oo   +14 more
openalex   +1 more source

IL-21 initiates an alternative pathway to induce proinflammatory TH17 cells

Nature, 2007
T. Korn, E. Bettelli, Wenda Gao, A. Awasthi, A. Jäger, T. Strom, M. Oukka, V. Kuchroo   +7 more
semanticscholar   +1 more source

Gene expression signatures from single‐cell transcriptomics predict Sjögren's syndrome

iMetaOmics, EarlyView.
A machine learning‐based 12‐gene signature (SjS.Sig) was developed from scRNA‐seq data of PBMCs from Sjögren's syndrome patients. The model was validated using bulk RNA‐seq datasets and further confirmed through flow cytometry and qPCR analysis in an independent clinical cohort, demonstrating robust diagnostic potential.
Shumin Cheng, Ling Yan, Yilin Wu, Yan Li, Ziheng Ye, Zhen Zhang, Yi Zhang, Jingyun Ma, Yuhong Liang, Zhaofan Luo, Huacheng Wang, Meili Gao, Chao Qin, Ke Zhu, Yun Leng, Kamran Ullah, Jun Liang, Haiyan Yan, Guan Yang, Yingqian Mo, Bihui Huang   +20 more
wiley   +1 more source

Interleukin-17 in Health and Disease: Special Focus on Its Role in Autoimmune Hepatitis. [PDF]

Cells
Agoston Ş, Grama A, Onaciu A, Mititelu A, Benţa G, Pop TL.   +5 more
europepmc   +1 more source

Plasticity and Heterogeneity of TH17 Cells

, 2019
Anvita Singaraju
openalex   +1 more source

In Silico Screening of the Human Gut Metaproteome Identifies Th17-Promoting Peptides Encrypted in Proteins of Commensal Bacteria [PDF]

, 2017
Claudio Hidalgo-Cantabrana, Marco Antonio Moro‐García, Aitor Blanco‐Míguez, Florentino Fdez‐Riverola, Anália Lourenço, Rebeca Alonso‐Arias, Borja Sánchez   +6 more
openalex   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source