Results 221 to 230 of about 214,484 (310)

Interleukin-23 in lung and airway diseases: from pathogenesis to precision-guided therapeutic targeting. [PDF]

Front Pharmacol
Nayak BB, Rajesh R, Teppan J, Gogg T, Böhm E.   +4 more
europepmc   +1 more source

Phthalate Metabolite, Mono(2‐Ethyl‐5‐Hydroxyhexyl) Phthalate (MEHHP), Promotes Uterine‐Fibroid–Associated Phenotypes in Myometrial Stem Cell‐Derived 3D Organoids

Environmental Toxicology, EarlyView.
ABSTRACT This study investigates how phthalate exposure contributes to uterine fibroid (UF) development by studying the effects of the Mono‐(2‐ethyl‐5‐hydroxyhexyl) phthalate (MEHHP), a metabolite of Di(2‐ethylhexyl) phthalate, on myometrial stem cells (MMSCs).
Somayeh Vafaei, Mervat M. Omran, Qiwei Yang, Sandra Madueke‐Laveaux, Ami R. Zota, Ayman Al‐Hendy, Mohamed Ali   +6 more
wiley   +1 more source

Neutrophil membrane-coated and MMP2-responsive nanoparticles deliver PIM1 inhibitor to alleviate inflammatory arthritis through inhibiting Th17 cell differentiation. [PDF]

J Nanobiotechnology
Su Z, Chen Z, Lin J, Yu W, Zeng Y, Zhang W, Li Q, Lin Y, Liu Z, Zheng G, Li L, Xie Z.   +11 more
europepmc   +1 more source

Cell membrane‐coated nanoparticles for dermatological diseases

VIEW, EarlyView.
Skin disorders are challenging to treat due to complex barrier functions and limited conventional therapies. Biomimetic cell membrane‐coated nanoparticles (CM‐NPs) offer a superior nanomedicine approach by evading immune detection and enabling precise targeting.
Shuaijun Zou, Baojie Zhang, Yuanjie Zhu
wiley   +1 more source

Tissue and CD4 T cell subset dependence on the amino acid transporter SLC38A1. [PDF]

Cell Metab
Sugiura A, Beier KL, Chi C, Heintzman DR, Ye X, Wolf MM, Patterson AR, Cephus JY, Hong HS, Perera JM, Lyssiotis CA, Newcomb DC, Rathmell JC.   +12 more
europepmc   +1 more source

Associations between gut microbiota and immune markers in pediatric multiple sclerosis and controls [PDF]

, 2016
Fadrosh, Douglas, Farqui, Ali A, Graves, Jennifer S, Hart, Janace, Lynch, Susan, Roalstad, Shelly, Spencer, Collin, Tremlett, Helen, Waubant, Emmanuelle, Zamvil, Scott   +9 more
core  

The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li, Yue Li, Yan‐Jie Jiang, Ge‐Hua Zhang, Li‐Hong Chang   +4 more
wiley   +1 more source

CD4⁺ T-Cell-Intrinsic IL-6 Is Critical for Th17 Differentiation and Dampened Responsiveness to CD8⁺ T Cell-Mediated Suppression. [PDF]

Eur J Immunol
Vemulawada C, Kale K, Crawford MP, Karandikar NJ.   +3 more
europepmc   +1 more source

Virus-friendly Th17s

Journal of Experimental Medicine, 2009
openaire   +2 more sources