Results 261 to 270 of about 187,124 (359)

Triggering Receptor Expressed on Myeloid Cells‐2 Regulates Innate Lymphoid Cell Levels in Bleomycin‐Induced Pulmonary Fibrosis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Idiopathic pulmonary fibrosis, a pathological change causing poor outcomes, is not reversible despite current antifibrotic therapy. Emerging evidence suggests that innate lymphoid cells (ILCs) mediate lung inflammation and fibrosis after stimulation by endogenous factors.
Hsiao‐Chin Shen, Nien‐Jung Chen, Chuan‐Yen Sun, Wen‐Kuang Yu, Vincent Yi‐Fong Su, Wan‐Ling Yang, Wei‐Chih Chen, Kuang‐Yao Yang   +7 more
wiley   +1 more source

Regulatory T cells in primary sjögren disease: regulatory mechanisms and therapeutic prospects. [PDF]

Front Immunol
Chengzhi W, Yifan L, Songwei L, Mengmeng D, Keying Z, Huan L.   +5 more
europepmc   +1 more source

Osteoarthritis: An Immuno‐Inflammatory Disease‐Mechanisms of Immune Cell Dysregulation and Potential Therapeutic Strategies

Med Research, EarlyView.
This review summarizes the immuno‐inflammatory mechanisms driving the pathogenesis of osteoarthritis (OA), extending beyond the traditional view of OA as a purely degenerative disease to incorporate immune cell infiltration, inflammatory factor release, and the formation of a chronic low‐grade inflammatory microenvironment.
Qingqiang Lei, Xiaoxian Lou, Xu Su, Shubao Liu, Yanli Tong, Jie Chen, Xuerui Chen, Wenjun Mao, Hui Yu, Liangbin Lin   +9 more
wiley   +1 more source

Adalimumab Reprograms M1 Macrophages to Attenuate Th1/Th17 Responses in Behçet's Uveitis and Vogt-Koyanagi-Harada Syndrome. [PDF]

Invest Ophthalmol Vis Sci
Zhu Y, Yu Q, Ma Y, Huang L, Ding J, Gao X, Ma L, Zhang D, Zhang B, Wang S, Chu WK, Su G, Yang P.   +12 more
europepmc   +1 more source

Evaluation of the production of Th17, Th1 and Th2 cytokines by lymphocytes in patients with American cutaneous leishmaniasis. 2013. Dissertation (Master in Public Health

, 2013
Almeida, Amanda Ferreira de
openalex   +1 more source

CLEC14A correlates with neutrophil infiltration in hepatocellular carcinoma and mediates neutrophil recruitment across liver endothelial cells

The Journal of Pathology, EarlyView.
Abstract Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related deaths globally, and cases are predicted to rise dramatically over the next few years. Overcoming the immune microenvironment in HCC remains a challenge, and innate immune populations such as tumour‐associated neutrophils can potentially impair the success of immunotherapy ...
Joanne M O'Rourke, Dean Kavanagh, Ayla O'Keeffe, Kylie Savoye, Kaiyi Yang, Daniel A Patten, Catherine E Willoughby, Josep M Llovet, Georgiana Neag, Helen L Reeves, Peter W Hewett, Neena Kalia, Tahir Shah, Yuk Ting Ma, Kelly Hunter, Joe Flint, Jack L McMurray, Owen Cain, Fabian Spill, Derek A Mann, Amy J Naylor, Victoria Heath, Christopher J Weston, Roy Bicknell, Shishir Shetty   +24 more
wiley   +1 more source

Ustekinumab resistance in individuals with ulcerative colitis is associated with an alteration of a subset of proinflammatory mucosal regulatory T cells. [PDF]

Inflamm Bowel Dis
Briggs KC, Tam A, Chaaban L, Luo A, Kobeissi L, Lazarev M, Parian A, Chowdhury R, Selaru FM, Casella K, Shenderov E, Sears CL, Housseau F, Melia JMP, Pardoll DM.   +14 more
europepmc   +1 more source

The Airway Epithelial Barrier in Childhood Asthma: A Central Player in Glucocorticoid Therapy, Resistance, and Severe Asthma

Pediatric Discovery, EarlyView.
ABSTRACT Childhood asthma remains a global public health challenge with suboptimal control, despite the availability of inhaled corticosteroids (ICS) as first‐line therapy. Glucocorticoids suppress inflammation and protect the airway epithelial barrier (AEB) via genomic and nongenomic pathways.
Tangqiaochu Gan, Zhou Fu, Chao Niu
wiley   +1 more source

Chemoradiotherapy-induced Th17/IL-17 signaling correlates with therapeutic tolerance and early recurrence in cervical carcinoma. [PDF]

BMC Mol Cell Biol
Cao F, Li N.
europepmc   +1 more source