Th17 and Th17/Treg ratio at early HIV infection associate with protective HIV-specific CD8+ T-cell responses and disease progression [PDF]
, 2015 The aim of this study was to analyze Th17 and Treg subsets and their correlation with anti-HIV T-cell responses and clinical parameters during (acute/early) primary HIV infection (PHI) and up to one year post-infection (p.i).
Cahn, Pedro +13 more
core +1 more source
Update on regulation and effector functions of Th17 cells
F1000Research, 2018 T-helper cells that produce IL-17 are recognized as a significant subset within cell-mediated adaptive immunity. These cells are implicated in both the pathology of inflammatory disorders as well as the clearance of extracellular infections and the ...
I. Sandquist, J. Kolls
semanticscholar +1 more source
An Algorithmic Information Calculus for Causal Discovery and Reprogramming Systems [PDF]
arXiv, 2017 We demonstrate that the algorithmic information content of a system is deeply connected to its potential dynamics, thus affording an avenue for moving systems in the information-theoretic space and controlling them in the phase space. To this end we performed experiments and validated the results on (1) a very large set of small graphs, (2) a number of
arxiv
Parkinson disease is a TH17 dominant autoimmune disorder against accumulated alpha-synuclein [PDF]
arXiv, 2013 Parkinson disease is a very common neurodegenerative disorder. Patients usually undergo destruction of substantia nigra to develop typical symptoms such as resting tremor, hypokinesia, and rigidity. However, the exact mechanism of Parkinson disease is still unknown, so it is called idiopathic Parkinsonism.
arxiv
Pathways and gene networks mediating the regulatory effects of cannabidiol, a nonpsychoactive cannabinoid, in autoimmune T cells. [PDF]
, 2016 BackgroundOur previous studies showed that the non-psychoactive cannabinoid, cannabidiol (CBD), ameliorates the clinical symptoms in mouse myelin oligodendrocyte glycoprotein (MOG)35-55-induced experimental autoimmune encephalomyelitis model of multiple ...
Coppola, Giovanni +5 more
core +2 more sources
The Equivocal Role of Th17 Cells and Neutrophils on Immunopathogenesis of Leishmaniasis
Frontiers in Immunology, 2017 Advances in the understanding of leishmaniasis progression indicate that cellular interactions more complex than the Th1/Th2 paradigm define the course of infection.
Suênia da C. Gonçalves-de-Albuquerque +7 more
semanticscholar +1 more source
Th17 cells demonstrate stable cytokine production in a proallergic environment [PDF]
, 2014 Th17 cells are critical for the clearance of extracellular bacteria and fungi, but also contribute to the pathology of autoimmune diseases and allergic inflammation. After exposure to an appropriate cytokine environment, Th17 cells can acquire a Th1-like
Awe, Olufolakemi +7 more
core +1 more source
Cell Death and Disease, 2017 Endometriosis is an estrogen-dependent inflammatory disease. The anti-inflammatory cytokine IL-10 is also increased in endometriosis. IL-10 production by Th17 cells is critical for limiting autoimmunity and inflammatory responses.
Kaikai Chang +11 more
semanticscholar +1 more source
Bronchoalveolar Lavage Fluid IFN-γ+ Th17 Cells and Regulatory T Cells in Pulmonary Sarcoidosis
Mediators of Inflammation, 2014 In sarcoidosis, increased Th17 cell fractions have been reported in bronchoalveolar lavage fluid, and elevated numbers of Th17 cells producing IFN-γ have been observed in peripheral blood.
Anders Tøndell +5 more
doaj +1 more source
Histamine and Histamine H4 Receptor Promotes Osteoclastogenesis in Rheumatoid Arthritis. [PDF]
, 2017 Histamine H4 receptor (H4R) has immune-modulatory and chemotaxic effects in various immune cells. This study aimed to determine the osteoclastogenic role of H4R in rheumatoid arthritis (RA).
Firestein, Gary S +5 more
core +1 more source