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The Multifaceted Role of Th17 Lymphocytes and Their Associated Cytokines in Cancer [PDF]
Clinical and Developmental Immunology, 2013 While the role of T helper 17 lymphocytes (Th17) in the pathogenesis of autoimmune diseases and in infectious immunity has been relatively well defined, the impact of these cells and their associated cytokines on cancer development is still under debate.
Darya Alizadeh +2 more
doaj +9 more sources
Immunological balance between Treg and Th17 lymphocytes as a key element of type 1 diabetes progression in children [PDF]
Frontiers in Immunology, 2022 Type 1 diabetes (T1D) is autoimmune destruction of the beta cells of pancreatic islets. Due to complexity of that disease, the mechanisms leading to the tolerance breakdown are still not fully understood.
Aleksandra Starosz +6 more
doaj +5 more sources
Th17 Lymphocytes in Respiratory Syncytial Virus Infection [PDF]
Viruses, 2013 Infection by respiratory syncytial virus (RSV) affects approximately 33 million infants annually worldwide and is a major cause of hospitalizations. Helper T lymphocytes (Th) play a central role in the immune response during such infections.
Rizgar A. Mageed +4 more
doaj +8 more sources
Change of Th17 Lymphocytes and Treg/Th17 in Typical and Atypical Optic Neuritis. [PDF]
PLoS One, 2016 Background Typical and atypical optic neuritis (ON) are two clinical types of autoimmune inflammatory diseases of the optic nerve that causes acute vision loss, and are difficult to distinguish in their early stages.
Cong H +6 more
europepmc +8 more sources
Vitamin D, Th17 Lymphocytes, and Breast Cancer. [PDF]
Cancers (Basel), 2022 Simple Summary The effect of vitamin D3 on the development of breast cancer (favorable, ineffective, or even unfavorable) depends on many factors, such as age, menopausal status, or obesity.
Filip-Psurska B +3 more
europepmc +4 more sources
Regulatory T lymphocytes/Th17 lymphocytes imbalance in autism spectrum disorders: evidence from a meta-analysis. [PDF]
Mol Autism, 2021 Background Immune system dysfunction has been proposed to play a critical role in the pathophysiology of autism spectrum disorders (ASD). Conflicting reports of lymphocyte subpopulation abnormalities have been described in numerous studies of patients ...
Ellul P +8 more
europepmc +9 more sources
Th1, Th2 and Th17 lymphocytes in autoimmune thyreopathies [PDF]
Vnitřní lékařství, 2021 Among the most common organ-specific autoimmune diseases are autoimmune thyreopathies. We have focused on the importance of Th1, Th2 and Th17 lymphocytes in autoimmune thyroiditis (AT).
Karolína Absolonová +2 more
semanticscholar +4 more sources
Th17 Lymphocytes in Children with Asthma: Do They Influence Control? [PDF]
Pediatr Allergy Immunol Pulmonol, 2021 Background: Allergic asthma was considered as an inflammation mediated by specific CD4+ helper lymphocytes (Th2); however, this paradigm changed in 2005, when a third group of helper cells called Th17 cells were identified.
Moreno-Córdova V +3 more
europepmc +4 more sources
Disease Models & Mechanisms, 2020 High-salt intake and high-fructose intake are risk factors for hypertension via oxidative stress and inflammation. T helper (Th)17 lymphocytes play an important role in the development of hypertension.
Eunjo Lee +7 more
doaj +3 more sources
The potential role of Th17 lymphocytes in patients with psoriasis. [PDF]
An Bras Dermatol, 2018 Background Psoriasis is a chronic inflammatory disorder, characterized by increased keratinocyte proliferation due to abnormal differentiation of basal keratinocytes.
Mansouri M +3 more
europepmc +9 more sources