Results 131 to 140 of about 709,386 (365)
Engineered Tissue Models to Decode Host–Microbiota Interactions
Advanced Science, EarlyView.Host–Microbiota interactions in the human body. Created in BioRender. Ghezzi, C. (2025) https://BioRender.com/ihivskg. Abstract A mutualistic co‐evolution exists between the host and its associated microbiota in the human body. Bacteria establish ecological niches in various tissues of the body, locally influencing their physiology and functions, but ...
Miryam Adelfio +5 more
wiley +1 more source
ESTRIOL IN FUNCTIONAL MODULATION OF REGULATORY LYMPHOCYTES IN MULTIPLE SCLEROSIS
Медицинская иммунология, 2014 We studied effects of estriol (E3), at the doses corresponding to the I and III trimesters of pregnancy,upon expression of functional markers on T-regulatory (Treg) and Th17-producing (Th17) lymphocytes, aswell as the production of relevant cytokines by ...
I. V. Nekrasova +2 more
doaj +1 more source
MSCs relieve SLE by modulation of Th17 cells through MMPs–CCL2–CCR2–IL‐17 pathway
Rheumatology & Autoimmunity, 2021 Objective To explore the modulation of mesenchymal stem cells (MSCs) on T helper 17 (Th17) cells in systemic lupus erythematosus (SLE) and underlying mechanism.
Bo Jiang +4 more
doaj +1 more source
Targeting Inflammatory T Cells in Multiple Sclerosis: Current Therapies and Future Challenges [PDF]
, 2015 Multiple Sclerosis (MS) is an autoimmune inflammatory disorder of the Central Nervous System (CNS), affecting more than one million people worldwide. The pathogenesis of MS involves several genetic and environmental factors, which ultimately lead to ...
Tuosto, Loretta
core +1 more source
Advanced Science, EarlyView.This review explores how multi‐omics, visualization technologies, and AI drive CAR‐T therapy from the micro to the macro level, from preclinical studies to clinical applications. The convergence of these approaches provides deeper insight into CAR‐T cell mechanisms, aids in structural optimization, and significantly enhances treatment efficacy and ...
Yuting Gong +4 more
wiley +1 more source
The Journal of Dermatology, Volume 50, Issue 1, Page 89-93, January 2023., 2023 Abstract Chronic rhinosinusitis with nasal polyposis (CRSwNP) is a typical type‐2 inflammation involving T‐helper type‐2 cells and impairing quality of life due to nasal obstruction, discharge and reduced sense of smell. Recently, the anti‐IL4Rα antibody dupilumab was approved for CRSwNP.
David Chromy +7 more
wiley +1 more source
Renal FailurePurpose This study aimed to elucidate the role of USP25 in a mouse model of anti-glomerular basement membrane glomerulonephritis (anti-GBM GN).Methods USP25-deficient anti-GBM GN mice were generated, and their nephritis progression was monitored.
Ranran Xu +5 more
doaj +1 more source
Biochemistry and Biophysics Reports, 2023 Th17 cells triggered inflammation is a critical element in cerebral ischemic injury, and the gut microbiota intricately impacts T lymphocytes. Nevertheless, it remains unclear whether the gut microbiota involves in cardiac arrest/cardiopulmonary ...
Qin Yuan +7 more
doaj
Parkinson disease is a TH17 dominant autoimmune disorder against accumulated alpha-synuclein [PDF]
arXiv, 2013 Parkinson disease is a very common neurodegenerative disorder. Patients usually undergo destruction of substantia nigra to develop typical symptoms such as resting tremor, hypokinesia, and rigidity. However, the exact mechanism of Parkinson disease is still unknown, so it is called idiopathic Parkinsonism.
arxiv
Thrombospondin-1/CD47 interaction regulates Th17 and treg differentiation in psoriasis [PDF]
, 2019 Accumulating evidence on the role of Thrombospondin-1 (TSP-1) in the immune response has emerged during the last years. In spite of the importance of TSP-1 not only as anti-angiogenic factor but also as an immunomodulatory molecule, studies on the ...
Calzada, María J. +11 more
core +2 more sources