Divergent Annexin A1 expression in periphery and gut is associated with systemic immune activation and impaired gut immune response during SIV infection. [PDF]
, 2016 HIV-1 disease progression is paradoxically characterized by systemic chronic immune activation and gut mucosal immune dysfunction, which is not fully defined.
Dandekar, Satya +6 more
core +1 more source
Scientific Reports, 2021 The immune response is critical in NAFLD pathogenesis, but the liver infiltrate’s composition and the role of each T cell population is still up for debate.
Victoria Cairoli +10 more
doaj +1 more source
Cutting Edge : Failure of Antigen-Specific CD4+ T Cell Recruitment to the Kidney during Systemic Candidiasis [PDF]
, 2014 Copyright © 2014 The Authors. Acknowledgments We thank E. Bolton and H. Bagavant for reagents and advice. We also acknowledge the staff of the Medical Research Facility at the University of Aberdeen for care of the animals used in this study.
Brown, Gordon D +5 more
core +2 more sources
The parasitic helminth product ES-62 suppresses pathogenesis in collagen-induced arthritis by targeting the interleukin-17–producing cellular network at multiple sites [PDF]
, 2012 Among many survival strategies, parasitic worms secrete molecules to modulate host immune responses. One such product, ES-62, is protective in the collagen-induced arthritis (CIA) model of rheumatoid arthritis.
Al-Riyami +47 more
core +1 more source
Immune response to Bifidobacterium bifidum strains support Treg/Th17 plasticity.
PLoS ONE, 2011 In this work we analyzed the immune activation properties of different Bifidobacterium strains in order to establish their ability as inductors of specific effector (Th) or regulatory (Treg) responses. First, we determined the cytokine pattern induced by
Patricia López +4 more
doaj +1 more source
Immunomodulation by Bifidobacterium infantis 35624 in the murine lamina propria requires retinoic acid-dependent and independent mechanisms. [PDF]
PLoS ONE, 2013 Appropriate dendritic cell processing of the microbiota promotes intestinal homeostasis and protects against aberrant inflammatory responses. Mucosal CD103(+) dendritic cells are able to produce retinoic acid from retinal, however their role in vivo and ...
Patrycja Konieczna +7 more
doaj +1 more source
Domination of Th17 subpopulation of lymphocytes during tumor progression.
Frontiers in Immunology, 2013 Maryam Ajami +2 more
openalex +2 more sources
HIV-Infected Subjects With Poor CD4 T-Cell Recovery Despite Effective Therapy Express High Levels of OX40 and α4β7 on CD4 T-Cells Prior Therapy Initiation [PDF]
, 2018 Background HIV-infected subjects with suboptimal CD4 restoration despite suppressive combined antiretroviral treatment (cART) (immunodiscordant subjects) have been classically characterized after a variable period of time under cART.
Genebat González, Miguel +10 more
core +1 more source
Ultrasound inflammatory parameters and Treg/Th17 cell profiles in established rheumatoid arthritis
Advances in Rheumatology, 2019 Background Imbalance and disfuntion in regulatory T-cells (Tregs) and IL-17 producer lymphocytes (Th17) have been implicated in the pathogenesis of rheumatoid arthritis (RA).
Aline Defaveri do Prado +9 more
doaj +1 more source
Pathogenesis of polymyalgia rheumatica [PDF]
, 2018 Polymyalgia rheumatica (PMR) is a chronic, inflammatory disorder of unknown cause, almost exclusively occurring in people aged over 50 and often associated with giant cell arteritis.
Ciccia F. +4 more
core +1 more source