Immunopathogenesis of canine chronic ulcerative stomatitis. [PDF]
Canine Chronic Ulcerative Stomatitis is a spontaneously occurring inflammatory disease of the oral mucosa. An immune-mediated pathogenesis is suspected though not yet proven.
Anderson, JG +8 more
core +1 more source
Yin and yang of interleukin-17 in host immunity to infection [version 1; referees: 2 approved] [PDF]
The interleukin-17 (IL-17) family cytokines, such as IL-17A and IL-17F, play important protective roles in host immune response to a variety of infections such as bacterial, fungal, parasitic, and viral.
Das, Shibali, Khader, Shabaana
core +3 more sources
Isolation and preliminary characterization of bovine Th17 lymphocytes
Interleukin 17A-producing T helper cells (Th17) are effector memory CD4+ T cells that are crucial to adaptive immunity to extracellular bacteria. The activities of these cells in the bovine species are not yet defined for want of straightforward cultivation and isolation procedures.
Patricia Cunha +4 more
openalex +3 more sources
Diabetes mellitus type 2 is one of the most important non-infectious diseases in the modern world, being an important risk factor of cardiovascular disorders.
I. V. Kologrivova +5 more
doaj +1 more source
Th17 cells triggered inflammation is a critical element in cerebral ischemic injury, and the gut microbiota intricately impacts T lymphocytes. Nevertheless, it remains unclear whether the gut microbiota involves in cardiac arrest/cardiopulmonary ...
Qin Yuan +7 more
doaj +1 more source
Role of Th17 lymphocytes in pathogenesis of colorectal cancer
Colorectal cancer (CRC) is estimated to be the first leading cause of death from cancer among men and women in the EU. Every year in Poland, 15,254 cases of CRC are diagnosed, and 10,501 patients die of the disease, making it the second leading cause of death from cancer.
Jacek, Karczewski +3 more
openaire +2 more sources
Pathogenicity of In Vivo Generated Intestinal Th17 Lymphocytes is IFNγ Dependent [PDF]
T helper 17 [Th17] cells are crucially involved in the immunopathogenesis of inflammatory bowel diseases in humans. Nevertheless, pharmacological blockade of interleukin 17A [IL17A], the Th17 signature cytokine, yielded negative results in patients with Crohn's disease [CD], and attempts to elucidate the determinants of Th17 cells' pathogenicity in the
Nizzoli, Giulia +16 more
openaire +2 more sources
The parasitic worm product ES-62 up-regulates IL-22 production by γδ T cells in the murine model of Collagen-Induced Arthritis [PDF]
S-62 is a phosphorylcholine (PC)-containing glycoprotein secreted by the filarial nematode Acanthocheilonema viteae that acts to modulate the host immune response to promote the establishment of chronic helminth infection.
Harnett, Margaret +2 more
core +1 more source
Vitamin D supplementation in systemic lupus erythematosus patients with vitamin D deficiency and insufficiency : the effect on disease activity, fatigue and interferon signature gene expression [PDF]
Background: Vitamin D deficiency is highly prevalent among patients with systemic lupus erythematosus (SLE) [1]. Evidence from multiple studies has shown that vitamin D deficiency in SLE is associated with a higher disease activity [2].
Borg, Andrew +4 more
core +1 more source
Tregs and Th17 lymphocytes in human DYRK1A haploinsufficiency
The DYRK1A gene encodes for a dual-specific tyrosine phosphorylation-regulated kinase 1A involved in different cellular processes such as cell differentiation, proliferation and survival. This tyrosine kinase plays a key role in brain growth and function.
Erica Valencic +7 more
openalex +6 more sources

