Results 91 to 100 of about 198,196 (300)

Human IL-10–producing Th1 cells exhibit a molecular signature distinct from Tr1 cells in malaria

, 2023
Control of intracellular parasites responsible for malaria requires host IFN-γ+T-bet+CD4+ T cells (Th1 cells) with IL-10 produced by Th1 cells to mitigate the pathology induced by this inflammatory response.
Chauhan, SB, Corvino, D, McCarthy, JS, Na, J, Hill, GR, Johnston, RL, de Oca, MM, Frame, TCM, Bukali, L, Wang, Y, Engel, JA, Zhang, P, Singh, SS, Soon, MSF, Loughland, JR, Engwerda, CR, Kuns, R, Ng, SS, Bunn, PT, Mukhopadhay, P, Kumar, R, Waddell, N, Koufariotis, LT, de Labastida Rivera, F, Amante, FH, Boyle, MJ, Edwards, CL, Lee, JS   +27 more
core   +1 more source

Increased Th1/Th17 Responses Contribute to Low-Grade Inflammation in Age-Related Macular Degeneration

Cellular Physiology and Biochemistry, 2017
Background/Aims: Age-related macular degeneration (AMD) is the primary cause of senior blindness in developed countries. Mechanisms underlying initiation and development of AMD remained known.
Jiajia Chen, Wenzhan Wang, Qiuming Li
doaj   +1 more source

Tumor‐Infiltrating mregDCs Restrain Anti‐Tumor Immunity in Early Relapse HCC

Advanced Science, EarlyView.
Tumor‐infiltrating mregDCs are regulated by the TNFR2‐non‐canonical NF‐κB axis, which is mediated by TNF‐α secreted by CD161+CD8+ T cells. These mregDCs recruit CD161+CD8+ T cells via the CCL20‐CCR6 axis, forming a positive feedback loop that enhances immunosuppression, promotes early recurrence of HCC, and further confirms TNFR2 as a key therapeutic ...
Zefan Zhang, Lin Ding, Yu Zhong, Haokang Feng, Linglong Huang, Waidong Huang, Chunqing Wang, Arne Östman, Beili Wang, Jian Zhou, Jia Fan, Wei Guo, Liang Wu, Yunfan Sun   +13 more
wiley   +1 more source

Adherence of adoptively transferred alloreactive Th1 cells in lung: partial dependence on LFA-1 and ICAM-1

, 2000
T helper type 1 (Th1) cells are important effectors in a number of immune-mediated lung diseases. We recently described a murine model of lung injury induced by adoptive transfer of cloned alloreactive Th1 cells. To investigate mechanisms that result in
Anne E. Dixon, Robert C. Hackman, Janis B. Mandac, Paul J. Martin, Joan G. Clark, David K. Madtes   +5 more
core   +1 more source

Th1 cell

Citation: 'Th1 cell' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13718 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Extra Climate Benefits From Afforestation Due to Reduced Forest Fragmentation in China

Advanced Science, EarlyView.
Afforestation in China reduced forest fragmentation in 2015, transforming 51.8 M ha of edge forests into interior forests. This enhanced carbon sequestration (1.4±0.2 Pg CO2e, a cooling biogeochemical effect), while reduced albedo (−0.9 Pg CO2e, a warming biophysical effect) partially offset the gain, yielding a net extra climate benefit of ...
Nan Meng, Wei Li, Philippe Ciais, Martin Brandt, Xiaowei Tong, Yanzheng Yang, Guofeng Shen, Wei Du, Lei Zhu, Yi Leng, Minxuan Sun, Mengjie Han, Xuemei Zhang, Jie Zhang, Nan Wang, Dan Tong, Chao Wu, Wenhao Dong, Shu Tao, Bo Pan   +19 more
wiley   +1 more source

Proportion of Th17/Th1 cells in RA.

, 2013
CD4+ T cells were isolated from the peripheral blood of healthy controls (HCPB) (n = 53), the peripheral blood of early RA patients (eRAPB) (n = 33), the peripheral blood of established RA patients (RAPB) (n = 20) and the synovial fluid of established RA
María-Belén Bautista-Caro (312513), Irene Arroyo-Villa (312512), Laura Nuño (310348), María-Eugenia Miranda-Carús (312518), Pilar Aguado-Acín (312514), Alejandro Balsa (118675), Emilio Martín-Mola (312517), Amaya Puig-Kröger (312516), María-Gema Bonilla-Hernán (312515)   +8 more
core   +1 more source

Th1/Th2 Cells in Patients with Multiple Myeloma

Hematology, 2004
Multiple myeloma (MM) is a lymphoproliferative disorder that is characterized by a proliferation of clonal B cells in various stages of maturation that then infiltrate the bone marrow. MM has been reported to accompany various T cell abnormalities including quantitative and functional defects of CD4+ and CD8+ T cells.
Hirokazu, Murakami, Hatsue, Ogawara, Handa, Hiroshi   +2 more
openaire   +2 more sources

Biodegradable Zn‐Based Implants: Progress, Challenges, and Pathways toward Clinical Translation

Advanced Science, EarlyView.
Exploring biodegradable Zn‐based implants offers a promising pathway to next‐generation biomedical devices with balanced degradation and biocompatibility. A comprehensive overview of biodegradable Zn‐based implants, covering their biological significance, material design principles, and advanced engineering strategies is provided.
Panfeng Zhao, Zhengquan Wang, Hui Yang, Xiyuan Zhang, Hanyuan Liu, Xiaotong Lu, Xiaocheng Li, Yanyan Liu, Xi Zhao, Wenhao Zhou, Yufeng Zheng   +10 more
wiley   +1 more source

CD152 enhances chemotaxis of Th1 cells.

, 2013
(A) Migration of unpolarized T cells. Recall response of CD4+ OVA-specific TCRtg T cells from CD152−/− or CD152+/+ mice was induced by adding 1 µg/ml OVA323–339 and T cell-depleted APCs.
Alf Hamann (8747), Gudrun F. Debes (372537), Holger Hoff (3391), Paula Kolar (372532), Frank Maszyna (372530), Monika C. Brunner-Weinzierl (330400), Arnhild Schrage (372535), Karin Knieke (330397)   +7 more
core   +1 more source