Results 91 to 100 of about 4,626,188 (194)

New Insights into HIV Life Cycle, Th1/Th2 Shift during HIV Infection and Preferential Virus Infection of Th2 Cells: Implications of Early HIV Treatment Initiation and Care

Life
The theory of immune regulation involves a homeostatic balance between T-helper 1 (Th1) and T-helper 2 (Th2) responses. The Th1 and Th2 theories were introduced in 1986 as a result of studies in mice, whereby T-helper cell subsets were found to direct ...
Joseph Hokello, Kratika Tyagi, Richard Oriko Owor, Adhikarimayum Lakhikumar Sharma, Alok Bhushan, Rene Daniel, Mudit Tyagi   +6 more
doaj   +1 more source

Co-adjuvanting DDA/TDB liposomes with a TLR7 agonist allows for IgG2a/c class-switching in the absence of Th1 cells. [PDF]

NPJ Vaccines, 2023
Zimmermann J, van Haren SD, Diray-Arce J, Adriawan IR, Wørzner K, Krog RT, Guleed S, Hu T, Mortensen R, Dietrich J, Solbak SMØ, Levy O, Christensen D, Pedersen GK.   +13 more
europepmc   +1 more source

Th1 Cells Alter the Inflammatory Signature of IL-6 by Channeling STAT Transcription Factors to Alu-like Retroelements. [PDF]

J Immunol, 2023
Millrine D, Cardus Figueras A, Uceda Fernandez J, Andrews R, Szomolay B, Cossins BC, Rice CM, Li J, Tyrrell VJ, McLeod L, Holmans P, O'Donnell VB, Taylor PR, Turner SJ, Jenkins BJ, Jones GW, Topley N, Williams NM, Jones SA.   +18 more
europepmc   +1 more source

Elevated profiles of peripheral Th22, Th17, Th2 cells, and decreased percentage of Th1 cells in breast cancer patients. [PDF]

Thorac Cancer, 2023
Peng Z, Dong X, He M, Zhao Y, Liu Y, Li M, Li G, Wang X, Li L, Hu Y.   +9 more
europepmc   +1 more source

Intrinsic STING Switches off Pathogenetic Programs of Th1 Cells to Inhibit Colitis. [PDF]

Cell Mol Gastroenterol Hepatol, 2023
Yang W, Yu T, Zhou G, Yao S, Wakamiya M, Hu H, Paessler S, Sun J, Cong Y.   +8 more
europepmc   +1 more source

P2RX7 signaling drives the differentiation of Th1 cells through metabolic reprogramming for aerobic glycolysis. [PDF]

Front Immunol, 2023
de Salles ÉM, Raeder PL, Angeli CB, Santiago VF, de Souza CN, Ramalho T, Câmara NOS, Palmisano G, Álvarez JM, D'Império Lima MR.   +9 more
europepmc   +1 more source

Id3 expression identifies CD4⁺ memory Th1 cells. [PDF]

Proc Natl Acad Sci U S A, 2022
Shaw LA, Deng TZ, Omilusik KD, Takehara KK, Nguyen QP, Goldrath AW.   +5 more
europepmc   +1 more source

Syntenin-1-mediated arthritogenicity is advanced by reprogramming RA metabolic macrophages and Th1 cells. [PDF]

Ann Rheum Dis, 2023
Meyer A, Sienes RE, Nijim W, Zanotti B, Umar S, Volin MV, Van Raemdonck K, Lewis M, Pitzalis C, Arami S, Al-Awqati M, Chang HJ, Jetanalin P, Schett G, Sweiss N, Shahrara S.   +15 more
europepmc   +1 more source

Natural Killer Cell Granule Protein (NKG7) promotes the development of vaccine-induced anti-fungal Th1 cells. [PDF]

PLoS Pathog
Wüthrich M, Taira CL, Dos Santos Dias L, He X, Lichtenberger S, Klein BS.   +5 more
europepmc   +1 more source

The FoxO4/DKK3 axis represses IFN-γ expression by Th1 cells and limits antimicrobial immunity. [PDF]

J Clin Invest, 2022
Chen X, Hu J, Wang Y, Lee Y, Zhao X, Lu H, Zhu G, Wang H, Jiang Y, Liu F, Chen Y, Kim BS, Zhou Q, Liu X, Wang X, Chang SH, Dong C.   +16 more
europepmc   +1 more source