Results 81 to 90 of about 4,626,188 (194)

Pro- and anti-inflammatory cytokines in threatened miscarriages [PDF]

, 2011
OBJECTIVE: The purpose of this study was to evaluate circulating and intracellular levels of Th1 and Th2 cytokines in women with threatenedmiscarriage (TM) and subsequent outcome.
Jean Calleja-Agius, Arnold R. Pizzey, Calleja-Agius, Jean, Jauniaux, Eric R.M., Shanthi Muttukrishna, Eric Jauniaux, Muttukrishna, Shanthi, Pizzey, Arnold R.   +7 more
core   +1 more source

IL-10-producing Th1 cells possess a distinct molecular signature in malaria. [PDF]

J Clin Invest, 2023
Edwards CL, Ng SS, de Labastida Rivera F, Corvino D, Engel JA, Montes de Oca M, Bukali L, Frame TC, Bunn PT, Chauhan SB, Singh SS, Wang Y, Na J, Amante FH, Loughland JR, Soon MS, Waddell N, Mukhopadhay P, Koufariotis LT, Johnston RL, Lee JS, Kuns R, Zhang P, Boyle MJ, Hill GR, McCarthy JS, Kumar R, Engwerda CR.   +27 more
europepmc   +2 more sources

Non-coding RNA and transcriptional regulation in CD4 T cell lineages [PDF]

, 2015
CD4 T cell lineage choice epitomises the ability of the immune system to become tailored to a specific threat and provides a framework for understanding the mechanisms behind cell specification.
Evans, CM
core  

Treg-derived IFN-γ supports the differentiation of Th1-Treg in tumor immunity and autoimmunity

Frontiers in Immunology
Regulatory T cells (Tregs) within the tumor microenvironment (TME) exhibit functional heterogeneity, including a Foxp3+T-bet+ subset known as Th1-type Treg (Th1-Treg) cells that exert potent immunosuppressive activity.
Ayumi Kuratani, Ayumi Kuratani, Masaaki Okamoto, Sekar Arumsari, Sekar Arumsari, Takashi Kobayashi, Takashi Kobayashi, Miwa Sasai, Miwa Sasai, Miwa Sasai, Masahiro Yamamoto, Masahiro Yamamoto, Masahiro Yamamoto   +12 more
doaj   +1 more source

The Imbalance between Foxp3+Tregs and Th1/Th17/Th22 Cells in Patients with Newly Diagnosed Autoimmune Hepatitis

Journal of Immunology Research, 2018
This study is aimed at examining the potential role of regulatory T- (Treg-) Th1-Th17-Th22 cells in the pathogenic process of autoimmune hepatitis (AIH). The numbers of Foxp3+Tregs and Th1, Th17, and Th22 cells were measured in 32 AIH patients using flow
Ma Liang, Zhang Liwen, Zhuang Yun, Ding Yanbo, Chen Jianping   +4 more
doaj   +1 more source

Modes of the initiation of T cell-mediated immune responses

Medical Review
T cell-mediated immune response is the center of adaptive immunity. Despite more than five decades of research, the knowledge of mechanisms drives the initiation of T cell-mediated immune response is still limited due to the complexity of T cell-mediated
Li Long, Yao Zhi
doaj   +1 more source

IL-9 Secreted by Leukemia Stem Cells Induces Th1-Skewed CD4+ T-Cells, which Promote Their Expansion. [PDF]

In acute myeloid leukemia (AML), leukemia stem and progenitor cells (LSCs and LPCs) interact with various cell types in the bone marrow (BM) microenvironment, regulating their expansion and differentiation.
Abbas, Hussein A, Wang, Bofei, Riether, Carsten, Radpour, Ramin, Simillion, Cedric, Ochsenbein, Adrian   +5 more
core   +2 more sources

NFIL3/Tim3 axis regulates effector Th1 inflammation in COPD mice

Frontiers in Immunology
BackgroundIFN-γ+CD4+ cells (type 1 helper T cells, Th1) represent a critical component of the inflammatory environment in the lungs of chronic obstructive pulmonary disease (COPD). Identifying influencing factors related to COPD-associated Th1 cells will
Junyi Ke, Junyi Ke, Shu Huang, Shu Huang, Zhixiong He, Siyu Lei, Siyu Lei, Shiya Lin, Yinying Li, Qiuming Li, Hui Huang, Hongchun Huang, Huajiao Qin, Minchao Duan   +13 more
doaj   +1 more source

Th1 cells inducing IFNγ response improves immunotherapy efficacy in gastric cancer. [PDF]

Chin J Cancer Res, 2023
Cao Q, Xue R, Zhang N.
europepmc   +1 more source

The emerging role of Th1 cells in atherosclerosis and its implications for therapy. [PDF]

Front Immunol, 2022
Chen J, Xiang X, Nie L, Guo X, Zhang F, Wen C, Xia Y, Mao L.   +7 more
europepmc   +1 more source