Results 71 to 80 of about 4,626,188 (194)
Cellular Physiology and Biochemistry, 2017 Background/Aims: Age-related macular degeneration (AMD) is the primary cause of senior blindness in developed countries. Mechanisms underlying initiation and development of AMD remained known.
Jiajia Chen, Wenzhan Wang, Qiuming Li
doaj +1 more source
IFN-gamma impairs release of IL-8 by IL-1beta-stimulated A549 lung carcinoma cells [PDF]
, 2008 Background Production of interferon (IFN)-gamma is key to efficient anti-tumor immunity. The present study was set out to investigate effects of IFNgamma on the release of the potent pro-angiogenic mediator IL-8 by human A549 lung carcinoma cells ...
Bernhard Zwissler +15 more
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Incomplete depletion and rapid regeneration of Foxp3+ regulatory T cells following anti-CD25 treatment in malaria-infected mice. [PDF]
, 2007 Investigation of the role of regulatory T cells (Treg) in model systems is facilitated by their depletion using anti-CD25 Abs, but there has been considerable debate about the effectiveness of this strategy.
Couper, Kevin N +9 more
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BMJ Open OphthalmologyIntroduction Rho-associated protein kinases (ROCKs) are a key regulator of T cell function, influencing a wide range of processes from activation to differentiation.
Tomohito Sato +5 more
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Th1 and Th2 cells in autoimmunity [PDF]
Clinical and Experimental Immunology, 1995 P, Druet, R, Sheela, L, Pelletier
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Do successful tuberculosis vaccines need to be immunoregulatory rather than merely Th1-boosting? [PDF]
, 2005 Tuberculosis vaccine candidates are entering clinical studies in areas where BCG fails. This is a high-risk strategy. We suggest that geographical variation in the efficacy of BCG is related to the presence in developing countries of a cross-reactive ...
Rook, GAW, Dheda, K, Zumla, A
core
Biological ResearchBackground CD4+ T cells play an important role in the initiation of an immune response by providing help to other cells. Among the helper T subsets, interferon-γ (IFN-γ)-secreting T helper 1 (Th1) and IL-17-secreting T helper 17 (Th17) cells are ...
Youra Kang +4 more
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Exploring the pathogenic potential of myelin-reactive Th1 and Th17 cells in central nervous system autoimmune disease [PDF]
, 2011 The activation of naïve T cells results in their proliferation and differentiation into a particular T-helper (Th) phenotype, namely Th1, Th2 or Th17 cells.
Prendergast, Catriona Taguma
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Citation: 'Th1 cell' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13718 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
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Astrocytes Modulate the Polarization of CD4+ T Cells to Th1 Cells
PLoS ONE, 2014 T-cell characteristics are dynamic and influenced by multiple factors. To test whether cells and the environment in the central nervous system (CNS) can influence T-cells, we tested if culturing mouse CD4(+) T-cells on mouse primary astrocytes, compared with standard feeder cells, modified T-cell polarization to Th1 and Treg subtypes.
Beurel, Eleonore +4 more
openaire +5 more sources