Results 151 to 160 of about 10,822,632 (330)

Targeting IL27RA Enhances Immunotherapy in Triple‐Negative Breast Cancer by Modulating Tumor Cells and the Tumor Microenvironment

open access: yesAdvanced Science, EarlyView.
IL27RA upregulation drives immune evasion in TNBC by suppressing MHC‐I expression and reprogramming T/NK‐cell states, establishing an immune‐excluded tumor phenotype. Targeting this epithelial‐intrinsic IL27RA–PI3K/AKT axis offers a promising strategy to overcome immunotherapy resistance.
Jiachi Xu   +8 more
wiley   +1 more source

Th1 Cells Alter the Inflammatory Signature of IL-6 by Channeling STAT Transcription Factors to Alu-like Retroelements. [PDF]

open access: yesJ Immunol, 2023
Millrine D   +18 more
europepmc   +1 more source

Early Th1 Cell Differentiation Is Marked by a Tfh Cell-like Transition [PDF]

open access: bronze, 2011
Shingo Nakayamada   +12 more
openalex   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

open access: yesAdvanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu   +11 more
wiley   +1 more source

Delivery of antigen in allogeneic cells preferentially generates CD4+ Th1 cells

open access: green, 2003
Javed N. Agrewala   +3 more
openalex   +2 more sources

Dead Matter, Living Machines: Repurposing Crustaceans' Abdomen Exoskeleton for Bio‐Hybrid Robots

open access: yesAdvanced Science, EarlyView.
Crustacean exoskeletons, repurposed from food waste, are engineered into sustainable bending actuators combining biotic structure with synthetic control. The augmented exoskeletons achieve rapid and robust motion with lightweight body and can be used as part of robotic manipulators, grippers and swimmers.
Sareum Kim, Kieran Gilday, Josie Hughes
wiley   +1 more source

Syntenin-1-mediated arthritogenicity is advanced by reprogramming RA metabolic macrophages and Th1 cells. [PDF]

open access: yesAnn Rheum Dis, 2023
Meyer A   +15 more
europepmc   +1 more source

3D‐MOF‐Lattice Inspired Programmable Metamaterials Based on Reconfigurable Polyhedral Origami

open access: yesAdvanced Science, EarlyView.
A novel metamaterial design strategy: inspired by MOFs crystal networks, creating reconfigurable modular polyhedral units to overcome the limitations of traditional materials. These modules exhibit adjustable stiffness, bistability, and Poisson's ratio that can be adjusted from negative to positive values.
Xi Kang   +5 more
wiley   +1 more source

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