Results 271 to 280 of about 10,689,174 (395)

An Off‐the‐Shelf Artificial Proregenerative Macrophage for Pressure Ulcer Treatment

open access: yesAdvanced Science, EarlyView.
Artificial macrophages (artM) by encapsulating M2 lysates into biodegradable PLGA microspheres and coated with macrophage membrane, are engineered as new therapeutics against skin pressure ulcer. In mouse models, the artM exhibited robust tissue repair through cell recruitment and microenvironment modulation, showing great therapeutic potential for ...
Qi Su   +12 more
wiley   +1 more source

Th1 cytokine pattern in sarcoidosis is expressed by bronchoalveolar CD4+ and CD8+ T cells [PDF]

open access: bronze, 2000
Antje Prasse   +6 more
openalex   +1 more source

Mechanisms of Baicalin Alleviates Intestinal Inflammation: Role of M1 Macrophage Polarization and Lactobacillus amylovorus

open access: yesAdvanced Science, EarlyView.
Baicalin alleviates E. coli‐induced intestinal inflammation through dual mechanisms: direct inhibition of the TLR4/IRF/STAT signaling pathway to modulate macrophage polarization and antigen presentation, thereby regulating Th17/Treg cell differentiation; and microbiota‐mediated indirect effects via increasing Lactobacillus amylovorus abundance and ...
Shunfen Zhang   +10 more
wiley   +1 more source

Th1-biased immune responses induced by DNA-based immunizations are mediated via action on professional antigen-presenting cells to up-regulate IL-12 production [PDF]

open access: bronze, 2000
Y. Asakura   +8 more
openalex   +1 more source

Biomimetic Nanoplatform for Targeted Rheumatoid Arthritis Therapy: Modulating Macrophage Niches Through Self‐Sustaining Positive Feedback‐Driven Drug Release Mechanisms

open access: yesAdvanced Science, Volume 12, Issue 15, April 17, 2025.
Rheumatoid arthritis is an incurable inflammatory autoimmune disease. The cleverly biomimetic nanoplatform integrates nanoenzymes and gene therapeutics and is sequentially modified by guanidinium‐based polymers and macrophage membranes, enhancing the gene silencing capability and reactive oxygen species scavenging efficiency through self‐sustaining ...
Huichao Xie   +12 more
wiley   +1 more source

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