Results 101 to 110 of about 401,370 (283)

Th2 and eosinophil responses suppress inflammatory arthritis

Nature Communications, 2016
Th2–eosinophil immune responses are well known for mediating host defence against helminths. Herein we describe a function of Th2–eosinophil responses in counteracting the development of arthritis.
Zhu Chen, D. Andreev, Katharina Oeser, Branislav Krljanac, A. Hueber, A. Kleyer, D. Voehringer, G. Schett, A. Bozec   +8 more
semanticscholar   +1 more source

Local cytokine transcription in naïve and previously infected sheep and lambs following challenge with Teladorsagia circumcincta [PDF]

, 2014
<b>Background</b><p></p> The abomasal helminth Teladorsagia circumcincta is one of the most economically important parasites affecting sheep in temperate regions.
Craig, Nicola M, Knight, Pamela A, Morrison, Ivan W, Pate, Judith A, Smith, David W   +4 more
core   +3 more sources

A Real-World Study of Tofacitinib in Indian Patients with Refractory Moderate-to-Severe Atopic Dermatitis, its Economic Considerations and Immunological Rationale

Indian Dermatology Online Journal
Background: The response of atopic dermatitis (AD) to different biologics and JAK inhibitors (JAKibs) is variable due to the varied immunological endotypes of AD.
Kabir Sardana, Savitha Sharath, Sumitra Kumari Meena, Ananta Khurana, Bhawuk Dhir   +4 more
doaj   +1 more source

Helminth-induced Th2 cell dysfunction is distinct from exhaustion and is maintained in the absence of antigen.

PLoS Neglected Tropical Diseases, 2019
T cell-intrinsic regulation, such as anergy, adaptive tolerance and exhaustion, is central to immune regulation. In contrast to Type 1 and Type 17 settings, knowledge of the intrinsic fate and function of Th2 cells in chronic Type 2 immune responses is ...
Johanna A Knipper, Alasdair Ivens, Matthew D Taylor   +2 more
doaj   +1 more source

Mercury: god of Th2 cells? [PDF]

Clinical and Experimental Immunology, 1995
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openaire   +2 more sources

Inhaled braylin regulates Th2 response and induces relaxant effects in the airway muscles in a model of ovalbumin-induced asthma

, 2023
Renan Fernandes do Espírito Santo, Cássio Santana Meira, Luı́za Carolina França Opretzka, Karoline Cristina Jatobá da Silva, Fênix Alexandra de Araújo, Rafael dos Santos Costa, Eudes S. Velozo, Fábio Rocha Formiga, Darízy Flávia Silva, Milena Botelho Pereira Soares, Cristiane Flora Villarreal   +10 more
openalex   +1 more source

The Primary Responses of Murine Neonatal Lymph Node CD4+ Cells are Th2-skewed and are Sufficient for the Development of Th2-biased Memory

Clinical and Developmental Immunology, 2003
Exposure of neonatal mice to antigen often results in Th2-biased responses in later life. Examples of this Th2 tendency are (a) secondary antibody responses dominated by the Th2-associated IgG1 isotype and (b) Th2-mediated tolerance to alloantigens.
Becky Adkins, Yurong Bu, Vladimir Vincek, Patricia Guevara   +3 more
doaj   +1 more source

In Vitro Generation of Interleukin 10–producing Regulatory CD4+ T Cells Is Induced by Immunosuppressive Drugs and Inhibited by T Helper Type 1 (Th1)– and Th2-inducing Cytokines

Journal of Experimental Medicine, 2002
We show that a combination of the immunosuppressive drugs, vitamin D3 and Dexamethasone, induced human and mouse naive CD4+ T cells to differentiate in vitro into regulatory T cells.
F. Barrat, D. Cua, A. Boonstra, D. Richards, C. Crain, H. Savelkoul, R. de Waal‐Malefyt, R. Coffman, C. Hawrylowicz, A. O’Garra   +9 more
semanticscholar   +1 more source

Perspectives on association of genetic polymorphism in Th1/Th2-related cytokines with the risk of oral precancerous lesions

, 2023
Yu Liu, Zhonglin Yu, Xi Yang, Wei Liu
openalex   +1 more source

Clinical impact of different classes of infiltrating T cytotoxic and helper cells (Th1, th2, treg, th17) in patients with colorectal cancer.

Cancer Research, 2011
The tumor microenvironment includes a complex network of immune T-cell subpopulations. In this study, we systematically analyzed the balance between cytotoxic T cells and different subsets of helper T cells in human colorectal cancers and we correlated ...
M. Tosolini, A. Kirilovsky, B. Mlecnik, T. Fredriksen, S. Mauger, G. Bindea, A. Berger, P. Bruneval, W. Fridman, F. Pagès, J. Galon   +10 more
semanticscholar   +1 more source