Results 201 to 210 of about 22,410 (257)

Comparative Analysis of Circulating and Synovial Immune Cells in Early Untreated Rheumatoid Arthritis and their relationship with molecular pathology and disease outcomes

Arthritis &Rheumatology, Accepted Article.
Objectives To assess the relationship of circulating and synovial immune cells with synovial molecular pathology and disease outcomes in early Rheumatoid Arthritis (RA). Methods Early (<12 months) treatment‐naïve RA patients (n=144) from the Pathobiology of Early Arthritis Cohort (PEAC) were included in this posthoc analysis.
Felice Rivellese, Elena Pontarini, Liliane Fossati‐Jimack, Rita A. Moura, Vasco C. Romão, João Eurico Fonseca, Alessandra Nerviani, Cankut Çubuk, Katriona Goldmann, Giovanni Giorli, Myles Lewis, Michele Bombardieri, Costantino Pitzalis, Pathobiology of Early Arthritis Cohort (PEAC) investigators   +13 more
wiley   +1 more source

Photo‐Induced Cracking in a Bi‐Component Molecular Solid: Capturing Structural Intermediates

Chemistry – An Asian Journal, Volume 20, Issue 9, May 2, 2025.
The concept of Long‐range Synthon Aufbau Modules (LSAM) is used to design photo‐responsive bi‐component solids. The design strategy is primarily based on tuning the structural parameters of a robust large synthon that leads to [2+2] photodimerization along with photo‐induced cracking. Captured structural intermediates reveal a possible reorientation of
Mollah Rohan Ahsan, Manish Kumar Mishra, Arijit Mukherjee   +2 more
wiley   +1 more source

Relevance of local Th2-type cytokine mRNA expression in immunocompetent infiltrates in inflamed gingival tissue to periodontal diseases

, 1997
Yusuke Tokoro, Y Matsuki, Tadashi Yamamoto, Tomoyasu Suzuki, Kohji Hara   +4 more
openalex   +2 more sources

Systemic T‐cell and local macrophage interactions mediate granule size‐dependent biological hydroxyapatite foreign body reaction

BMEMat, EarlyView.
This study expanded our understanding of the size effect of biological hydroxyapatite (BHA) granules from a biological perspective rather than physical defect accommodation. Besides, we proposed the multi‐level structure of commercially available BHA granules based on their microstructure and provided a biological mechanism for the classification of ...
Yixiong Lin, Yang Zou, Jieting Yang, Zongpu Han, Xinyu Guo, Xiaomeng Gao, Jieyun Xu, Zhuohong Gong, Ruizhi Li, Zhipeng Li, Baoxin Huang, Yin Xiao, Feilong Deng, Zetao Chen   +13 more
wiley   +1 more source

Breaking barriers: Smart vaccine platforms for cancer immunomodulation

Cancer Communications, Volume 45, Issue 5, Page 529-571, May 2025.
Abstract Despite significant advancements in cancer treatment, current therapies often fail to completely eradicate malignant cells. This shortfall underscores the urgent need to explore alternative approaches such as cancer vaccines. Leveraging the immune system's natural ability to target and kill cancer cells holds great therapeutic potential ...
Mohammad Mahmoudi Gomari, Taha Ghantabpour, Nima Pourgholam, Neda Rostami, Stephen M. Hatfield, Farzaneh Namazifar, Shadi Abkhiz, Seyed Sadegh Eslami, Mahsa Ramezanpour, Mahsa Darestanifarahani, Igor Astsaturov, Sidi A. Bencherif    +11 more
wiley   +1 more source

GRAFT-INFILTRATING T HELPER CELLS, CD45RC PHENOTYPE, AND TH1/TH2-RELATED CYTOKINES IN DONOR-SPECIFIC TRANSFUSION–INDUCED TOLERANCE IN ADULT RATS

, 1995
Régis Josien, Christophe Pannetier, Patrice Douillard, Diego Cantarovich, Séverine Ménoret, Laurence Bugeon, Philippe Kourilsky, Jean-Paul Soulillou, María Cristina Cuturi   +8 more
openalex   +1 more source

Immunosuppressive JAG2+ tumor‐associated neutrophils hamper PD‐1 blockade response in ovarian cancer by mediating the differentiation of effector regulatory T cells

Cancer Communications, EarlyView.
Abstract Background Tumor‐associated neutrophils (TANs) play a critical role in modulating immune responses and exhibit significant heterogeneity. Our previous study demonstrated that jagged canonical Notch ligand 2 (JAG2)+ TANs were associated with an immunosuppressive microenvironment in high‐grade serous ovarian cancer (HGSOC), but the underlying ...
Chenyang Wang, Moran Yang, Yujing Zhong, Kankan Cao, Xueling Wang, Chen Zhang, Yiying Wang, Mengdi He, Jiaqi Lu, Guodong Zhang, Yan Huang, Haiou Liu   +11 more
wiley   +1 more source

Preferential recognition of hepatitis B nucleocapsid antigens by Th1 or Th2 cells is epitope and major histocompatibility complex dependent

, 1995
David R. Milich, D L Peterson, F. Schödel, Joyce Jones, Janice Hughes   +4 more
openalex   +1 more source

Stabilization of a Terminal Hydride Through Regioselective Protonation in a Diiron Complex Inspired by [FeFe]‐Hydrogenase

Chemistry – A European Journal, Volume 31, Issue 18, March 25, 2025.
Acid strength and steric hindrance orients regioselective protonation of an electron‐rich dithiolate diiron complex, related to the H‐cluster. Weaker acids promote the main formation of an exceptionally stable terminal hydride complex, whereas stronger acids mostly favor a bridging hydride isomer. Abstract Protonation studies of the complex [Fe2(μ‐pdt)(
Lucile Chatelain, Sven T. Stripp, Philippe Schollhammer   +2 more
wiley   +1 more source

Recombinant Human Growth Hormone Modulates Th1 and Th2 Cytokine Response in Burned Mice

, 1998
Kazuya Takagi, F. Suzuki, Robert E. Barrow, Steven E. Wolf, David N. Herndon   +4 more
openalex   +2 more sources