Circulating Th22 and Th9 Levels in Patients with Acute Coronary Syndrome [PDF]
Background. CD4+ T helper (Th) cells play critical roles in the development and progression of atherosclerosis and the onset of acute coronary syndromes (ACS, including acute myocardial infarction (AMI) and unstable angina pectoris (UAP)). In addition to
Ying-zhong Lin +9 more
doaj +5 more sources
Th22 cells in allergic disease [PDF]
During the last decade, the field of T cell immunology started to confuse the scientific community. More and more subtypes of T helper cells and their counterparts in the innate immune system are described. We are just at the beginning to understand which specific function the distinct subtypes fulfill. Th22 cells are terminally differentiated and very
Eyerich, K., Eyerich, S.
core +9 more sources
Th17 and Th22 in Skin Allergy [PDF]
Development of eczematous skin reactions depends on disease-specific and time-dependent recruitment of a variety of leukocytes affecting resident skin cells through cytotoxic mechanisms and release of cytokines. Th17 and Th22, defined as RORC+IL-17+ and IL-17-IFN-γ-IL-22+ cells, respectively, belong to a newly identified class of lymphocytes ...
Andrea, Cavani +2 more
core +5 more sources
Differential human Th22-lymphocyte response triggered by Aggregatibacter actinomycetemcomitans serotypes [PDF]
In Aggregatibacter actinomycetemcomitans, different serotypes have been described based on lipopolysaccharide (LPS) antigenicity. When T lymphocytes were stimulated with these serotypes, different patterns of T-helper (Th)1 and Th17-type of immune responses were reported.
Díaz Zúñiga, Jaime +7 more
core +7 more sources
Circulating Th17, Th22, and Th1 Cells Are Increased in Psoriasis [PDF]
Th17, Th22, and Th1 cells are detected in psoriatic skin lesions and implicated in psoriasis pathogenesis, but inflammatory T cell numbers in blood, as well as the relative importance of each cell type, is unclear. Using 7-color flow cytometry, circulating Th17, Th22, and Th1 cells were quantified in 21 untreated psoriatics and 17 healthy individuals ...
Kagami, Shinji +4 more
openaire +4 more sources
Th22 cells are associated with hepatocellular carcinoma development and progression. [PDF]
IL-22-producing CD4(+) T helper cells (Th22 cells) have been identified as major inducers of tissue inflammation and immune responses. Currently, no previous study explored the role of Th22 cells in the pathogenesis of hepatocellular carcinoma (HCC).
Shanyu, Qin +5 more
openaire +3 more sources
Increased circulating Th22 cells correlated with Th17 cells in patients with severe preeclampsia [PDF]
Objective: We aimed to investigate Th22 cells and their association with Th17 and Treg cells in the etiology of severe preeclampsia (sPE). Methods: Thirty sPE patients and 30 healthy pregnant women were recruited in this study.
Zhan Zhang +6 more
doaj +2 more sources
Elevated peripheral frequencies of Th22 cells: a novel potent participant in obesity and type 2 diabetes. [PDF]
ObjectiveChronic low-grade inflammation has long been recognized as the central link between obesity and type 2 diabetes (T2D). The novel subset of T helper (Th) cells, Th22, plays an emerging role in chronic inflammation.
Ruxing Zhao +10 more
doaj +2 more sources
The NOTCH-HES-1 axis is involved in promoting Th22 cell differentiation [PDF]
Background NOTCH signaling has been shown to play a role in the production of interleukin-22 (IL-22) by CD4+ T cells. Multiple T-helper (Th) cell populations secrete IL-22.
Chong Zeng +7 more
doaj +3 more sources
The Imbalance between Foxp3+Tregs and Th1/Th17/Th22 Cells in Patients with Newly Diagnosed Autoimmune Hepatitis [PDF]
This study is aimed at examining the potential role of regulatory T- (Treg-) Th1-Th17-Th22 cells in the pathogenic process of autoimmune hepatitis (AIH). The numbers of Foxp3+Tregs and Th1, Th17, and Th22 cells were measured in 32 AIH patients using flow
Ma Liang +4 more
doaj +2 more sources

