Results 31 to 40 of about 7,483 (199)

Th17 and Th22 cells in psoriatic arthritis and psoriasis [PDF]

Arthritis Research & Therapy, 2013
Abstract Introduction The aim of this study was to characterize interleukin 17 (IL-17) and interleukin 22 (IL-22) producing cells in peripheral blood (PB), skin, synovial fluid (SF) and synovial tissue (ST) in patients with psoriasis (Ps) and psoriatic arthritis (PsA).
Benham, Helen, Norris, Paul, Goodall, Jane, Wechalekar, Mihir D., FitzGerald, Oliver, Szentpetery, Agnes, Smith, Malcolm, Thomas, Ranjeny, Gaston, Hill   +8 more
openaire   +6 more sources

Importance of Th22 Cell Disequilibrium in Immune Thrombocytopenic Purpura [PDF]

Medical Science Monitor, 2018
BACKGROUND The disequilibrium of T helper (Th) cells play an important role in the occurrence and development of immune thrombocytopenic purpura (ITP). Th22 cells, as a newly discovered subset of T lymphocytes, plays an important role in autoimmune disorders and inflammatory diseases.
Zhan, Feng-xia, Li, Juan, Fang, Min, Ding, Juan, Wang, Qian   +4 more
openaire   +2 more sources

Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling. [PDF]

, 2009
Th subsets are defined according to their production of lineage-indicating cytokines and functions. In this study, we have identified a subset of human Th cells that infiltrates the epidermis in individuals with inflammatory skin disorders and is ...
Eyerich, Stefanie;Eyerich, Kilian;Pennino, Davide;Carbone, Teresa;Nasorri, Francesca;Pallotta, Sabatino;Cianfarani, Francesca;Odorisio, Teresa;Traidl-Hoffmann, Claudia;Behrendt, Heidrun;Durham, Stephen R.;Schmidt-Weber, Carsten B.;Cavani, Andrea, Eyerich, S;Eyerich, K;Pennino, D;Carbone, T;Nasorri, F;Pallotta, S;Cianfarani, F;Odorisio, T;Traidl-Hoffmann, C;Behrendt, H;Durham, SR;Schmidt-Weber, CB;Cavani, A   +1 more
core   +3 more sources

MINOR SUBSETS OF T-HELPER CELLS (Th THYMIC NAIVE, Th CENTRAL NAIVE, Th9, Th22 AND CD4+CD8+ DOUBLE POSITIVE T-CELLS)

Медицинская иммунология, 2014
. T cell populations, specifically, T helper (Th) cells, are among key players in the processes occurring in the body following exposure to a foreign antigen. Usage of new, highly sensitive instruments allowed of more detailed studies of their structural
S. V. Khaidukov
doaj   +1 more source

The clinical significance of intrahepatic Th22 cells in liver cirrhosis [PDF]

Advances in Clinical and Experimental Medicine, 2019
Th22 cells are a recently identified CD4+ T helper subset and have been implicated in the pathogenesis of certain diseases in humans, but the role of Th22 cells in liver cirrhosis (LC) remains unclear.The aim of the study was to investigate the expression and clinical significance of intrahepatic Th22 cells in LC tissues.Samples of liver tissue of 20 ...
Shanyu, Qin, Mei, Chen, Xiaoyun, Guo, Wei, Luo, Jiaxu, Wang, Haixing, Jiang   +5 more
openaire   +2 more sources

Th22 Cells/IL-22 Serves as a Protumor Regulator to Drive Poor Prognosis through the JAK-STAT3/MAPK/AKT Signaling Pathway in Non-Small-Cell Lung Cancer

Journal of Immunology Research, 2022
The interaction of immune cells and cytokines in the tumor microenvironment affects the development and prognosis of tumors with an unclear potential regulatory mechanism.
Yinan Yao, Guangdie Yang, Guohua Lu, Jiani Ye, Luyun Cui, Zhu Zeng, Junjun Chen, Jianying Zhou   +7 more
doaj   +1 more source

Levels of Th17, Th22, and Th17/Th22 are more drastically depleted by SIV infection in RB than PBMC. [PDF]

, 2016
Comparison of frequencies (measured as percentages of total CD4+ T-cell populations) of circulating (A) and colorectal (B) Th17 (red), Th22 (blue), and Th17/Th22 (green) cells before (d.-20 p.i.) and after (d. 58 p.i.) SIV infection.
Luca Micci (427502), Mirko Paiardini (243070), Nicolas Chomont (175516), Rémi Fromentin (659658), Colleen S. McGary (430430), Sara Paganini (2172766), Emily S. Ryan (651787), Kirk Easley (356159)   +7 more
core   +1 more source

Acteoside relieves mesangial cell injury by regulating Th22 cell chemotaxis and proliferation in IgA nephropathy

Renal Failure, 2018
The existing therapies of IgA nephropathy are unsatisfying. Acteoside, the main component of Rehmannia glutinosa with anti-inflammatory and anti-immune effects, can improve urinary protein excretion and immune disorder.
Lu Gan, Xiaozhao Li, Mengyuan Zhu, Chen Chen, Huimin Luo, Qiaoling Zhou   +5 more
doaj   +1 more source

Serum Levels of Selected Th17 and Th22 Cytokines in Psoriatic Patients [PDF]

Disease Markers, 2013
Introduction. Psoriasis is a T cell-mediated inflammatory disease in which pathogenesis T helper (Th) lymphocytes (Th1, Th17, and Th22) play an important role. The aim of the study was to assess the serum levels of some cytokines involved in the Th17 and Th22 responses in psoriatic patients.Material and Methods.
Anna Michalak-Stoma, Joanna Bartosińska, Małgorzata Kowal, Maria Juszkiewicz-Borowiec, Agnieszka Gerkowicz, Grażyna Chodorowska   +5 more
openaire   +3 more sources

Th22 cells are expanded in multiple sclerosis and are resistant to IFN-β [PDF]

Journal of Leukocyte Biology, 2014
AbstractTh1 and Th17 cells have been considered as effectors in mouse EAE and in the human counterpart, MS. Recently, IL-22, a Th17-related, proinflammatory cytokine, has been associated with a new Th cell subset, defined as Th22, involved in chronic inflammatory conditions, such as psoriasis; the role of IL-22 in MS has not yet been elucidated.
Rolla S, Bardina V, De Mercanti S, Quaglino P, DE PALMA, Raffaele, Gned D, Brusa D, Durelli L, Novelli F, Clerico M.   +9 more
openaire   +4 more sources