Results 41 to 50 of about 7,483 (199)
Levels of Pathogenic Th17 and Th22 Cells in Patients with Rheumatoid Arthritis
Journal of Immunology Research, 2022 Rheumatoid arthritis (RA) is a chronic autoimmune condition characterized, among others, by tissue damage and activation/differentiation of proinflammatory lymphocytes. Accordingly, several studies have concluded that type 17 T helper (Th17) cells seem to have an important role in the pathogenesis of this condition.
Marlen Vitales-Noyola +7 more
openaire +3 more sources
Elevated Th22 Cells Correlated with Th17 Cells in Peripheral Blood of Patients with Acute Myeloid Leukemia [PDF]
, 2014 Acute myeloid leukemia (AML) is a hematological tumor in which progress T helper (Th) subsets including Th22, Th17, and Th1 cells play a pivotal role. However, the role of T helper (Th) subsets in the immune pathogenesis of AML remains unclear.
Chuanfang Liu +9 more
core +1 more source
PLoS ONE, 2013 BackgroundAtherosclerosis is a chronic inflammatory disease mediated by immune cells. Th22 cells are CD4(+) T cells that secret IL-22 but not IL-17 or IFN-γ and are implicated in the pathogenesis of inflammatory disease.
Lei Zhang +11 more
doaj +1 more source
Clinics, 2021 OBJECTIVES: To investigate the efficacy and potential molecular mechanism of Huangkui capsule in combination with leflunomide (HKL) for the treatment of immunoglobulin A nephropathy (IgAN) METHODS: IgAN rat models were constructed by treating rats with ...
Shuwen Pei, Yan Li
doaj +1 more source
The correlation between the percentages of Th17, Th22 and Th17/Th22 cells in patients. [PDF]
, 2013 The potential correlations among different subsets of CD4+ T cells were analyzed by Spearman rank correlation test. Data shown are the mean values of individual patients (n = 27).
Di Peng (432822) +4 more
core +1 more source
Staphylococcal Exotoxins Induce Interleukin 22 in Human Th22 Cells [PDF]
International Archives of Allergy and Immunology, 2014 Background: We have shown previously that T cells from atopic dermatitis (AD) patients produce more IL-22 upon staphylococcal exotoxin stimulation compared to psoriasis patients and healthy controls. The role of staphylococcal exotoxins on polarized memory T helper (Th)22 cells which are enriched in inflamed AD skin remains elusive.
Margarete Niebuhr +4 more
openaire +2 more sources
Th22 cell accumulation is associated with colorectal cancer development
World Journal of Gastroenterology, 2015 To investigate the expression of Th22 cells and related cytokines in colorectal cancer (CRC) tissues, and the probably mechanism.CRC tumor and paratumor tissues were collected to detect the expression levels of Th22 cells and of related cytokines by immunohistochemistry, flow cytometry and real-time quantitative polymerase chain reaction (RT-qPCR ...
Yong-Hong, Huang +4 more
openaire +2 more sources
Indian Dermatology Online JournalBackground: The response of atopic dermatitis (AD) to different biologics and JAK inhibitors (JAKibs) is variable due to the varied immunological endotypes of AD.
Kabir Sardana +4 more
doaj +1 more source
JAK Inhibitors in Psoriatic–Atopic Dermatitis Overlap: A Four‑Case Series
JEADV Clinical Practice, EarlyView.ABSTRACT Overlap between psoriasis and atopic dermatitis (AD) poses diagnostic and therapeutic challenges; monoclonal antibodies targeting a single axis may improve one component while worsening the other [1]. Janus kinase (JAK) inhibitors act pleiotropically and may provide simultaneous control of psoriatic and eczematous inflammation [2].
Eleonora Bongiovanni +6 more
wiley +1 more source
BMC Immunology, 2023 Background The immunity of CD4+ T cell subsets against human cytomegalovirus (HCMV) is considerable due to their essential role in controlling the infection in transplant individuals.
Yashgin Hassanzadeh +3 more
doaj +1 more source