Results 41 to 50 of about 8,035 (194)

Levels of Th17, Th22, and Th17/Th22 are more drastically depleted by SIV infection in RB than PBMC.

, 2016
Comparison of frequencies (measured as percentages of total CD4+ T-cell populations) of circulating (A) and colorectal (B) Th17 (red), Th22 (blue), and Th17/Th22 (green) cells before (d.-20 p.i.) and after (d. 58 p.i.) SIV infection.
Luca Micci (427502), Mirko Paiardini (243070), Nicolas Chomont (175516), Rémi Fromentin (659658), Colleen S. McGary (430430), Sara Paganini (2172766), Emily S. Ryan (651787), Kirk Easley (356159)   +7 more
core   +1 more source

Th22 Cells Promote Osteoclast Differentiation via Production of IL-22 in Rheumatoid Arthritis

Frontiers in Immunology, 2018
T helper (Th) cells can differentiate into functionally distinct subsets and play a pivotal role in inflammatory and autoimmune diseases such as rheumatoid arthritis (RA).
Yusuke Miyazaki, Shingo Nakayamada, Satoshi Kubo, Kazuhisa Nakano, Shigeru Iwata, Ippei Miyagawa, Xiaoxue Ma, Xiaoxue Ma, Gulzhan Trimova, Kei Sakata, Kei Sakata, Yoshiya Tanaka   +11 more
doaj   +1 more source

Circulating Th17, Th22, and Th1 Cells Are Elevated in the Guillain-Barré Syndrome and Downregulated by IVIg Treatments

Mediators of Inflammation, 2014
The Guillain-Barré syndrome (GBS) is considered a T helper 1 (Th1) cells-mediated acute inflammatory peripheral neuropathy. However, some changes in GBS could not be explained completely by Th1 cells pathogenic role.
Shujuan Li, Tao Jin, Hong-Liang Zhang, Hong Yu, Fanhua Meng, Hernan Concha Quezada, Jie Zhu   +6 more
doaj   +1 more source

Th22 cell accumulation is associated with colorectal cancer development

World Journal of Gastroenterology, 2015
To investigate the expression of Th22 cells and related cytokines in colorectal cancer (CRC) tissues, and the probably mechanism.CRC tumor and paratumor tissues were collected to detect the expression levels of Th22 cells and of related cytokines by immunohistochemistry, flow cytometry and real-time quantitative polymerase chain reaction (RT-qPCR ...
Yong-Hong, Huang, Yun-Fei, Cao, Zhi-Yuan, Jiang, Sen, Zhang, Feng, Gao   +4 more
openaire   +2 more sources

Staphylococcal Exotoxins Induce Interleukin 22 in Human Th22 Cells [PDF]

International Archives of Allergy and Immunology, 2014
Background: We have shown previously that T cells from atopic dermatitis (AD) patients produce more IL-22 upon staphylococcal exotoxin stimulation compared to psoriasis patients and healthy controls. The role of staphylococcal exotoxins on polarized memory T helper (Th)22 cells which are enriched in inflamed AD skin remains elusive.
Margarete Niebuhr, Julia Mainardy, Annice Heratizadeh, Imke Satzger, Thomas Werfel   +4 more
openaire   +2 more sources

A Real-World Study of Tofacitinib in Indian Patients with Refractory Moderate-to-Severe Atopic Dermatitis, its Economic Considerations and Immunological Rationale

Indian Dermatology Online Journal
Background: The response of atopic dermatitis (AD) to different biologics and JAK inhibitors (JAKibs) is variable due to the varied immunological endotypes of AD.
Kabir Sardana, Savitha Sharath, Sumitra Kumari Meena, Ananta Khurana, Bhawuk Dhir   +4 more
doaj   +1 more source

Decreased frequency of Th22 cells and IL-22 cytokine in kidney transplant patients with active cytomegalovirus infection

BMC Immunology, 2023
Background The immunity of CD4+ T cell subsets against human cytomegalovirus (HCMV) is considerable due to their essential role in controlling the infection in transplant individuals.
Yashgin Hassanzadeh, Ramin Yaghobi, Parviz Pakzad, Bita Geramizadeh   +3 more
doaj   +1 more source

Expression of Helper and Regulatory T Cells in Atopic Dermatitis: A Meta-Analysis

Frontiers in Pediatrics, 2022
BackgroundAtopic dermatitis (AD) is a common inflammatory skin disease, with the incidence peaks in infancy. A meta-analysis was performed to assess the levels of T helper type 22 (Th22) cells, T helper type 17 (Th17) cells, interleukin (IL)-17, and ...
Dao-jun Zhang, Fei Hao, Tian Qian, Hai-xing Cheng   +3 more
doaj   +1 more source

Autosomal Dominant Hyper‐IgE Syndrome Patients Retain IL10‐Producing preTh17‐Cells That Are Activated by Opportunistic Pathogens and Support IgE Production

Allergy, EarlyView.
IL‐10 producing CCR6+Th‐cells are central memory T‐cells that express ROR‐γt and differentiate to Th17‐cells via an autocrine loop of STAT3‐activating cytokines (preTh17). STAT3‐deficient AD‐HIES patients lack Th17‐ and Tfh17‐cells but retain preTh17‐ and Th1/17‐cells.
Giorgia Moschetti, Chiara Vasco, Francesca Clemente, Paola Larghi, Sara Maioli, Edoardo Scarpa, Elena Carelli, Nadia Pulvirenti, Maria Lucia Sarnicola, Mariacristina Crosti, Manal Bel Imam, Willem van de Veen, Loris Rizzello, Sergio Abrignani, Lucia A. Baselli, Rosa Maria Dellepiane, Maria Carrabba, Giovanna Fabio, Jens Geginat   +18 more
wiley   +1 more source

Serum‐Proteomic Profiling Reveals Distinct Atopic Dermatitis Severity‐Linked Signatures

Allergy, EarlyView.
This study aimed to identify a set of serum biomarkers that robustly distinguish prespecified severe from mild atopic dermatitis groups. Serum proteomic profiling distinguishes severe from mild atopic dermatitis, revealing an epithelial enriched severity footprint linked to LDH‐associated tissue injury and Th2/Th22 inflammation.
Jag S. Lally, Takeshi Yoshida, Shan Gao, Xueya Cai, Donald Y. M. Leung, Lisa A. Beck, Anna De Benedetto   +6 more
wiley   +1 more source