Results 61 to 70 of about 7,483 (199)

Th22 Cell Is a Gradually Proved Potential Biomarker for Acute Coronary Syndrome [PDF]

Mediators of Inflammation, 2014
Th22 cell, a novel human CD4+ T helper subset, has already been reported to play a vital role in the process of chronic inflammatory diseases such as rheumatoid arthritis (RA) and atherosclerosis (AS) [1, 2]. Interestingly, Th22 cells were also involved in acute coronary syndrome (ACS). Lin et al.
Ying Huang, Tao Xu, Jun Li
openaire   +3 more sources

A pro-inflammatory role for Th22 cells in Helicobacter pylori-associated gastritis [PDF]

, 2015
OBJECTIVE: Helper T (Th) cell responses are critical for the pathogenesis of Helicobacter pylori-induced gastritis. Th22 cells represent a newly discovered Th cell subset, but their relevance to H. pylori-induced gastritis is unknown.
Wang, TT, Peng, LS, Liu, T, Mao, XH, Yang, HJ, Cheng, P, Li, BS, Li, WH, Chen, W, Zou, QM, Liu, XF, Zeng, M, Mao, FY, Yang, SM, Zuo, QF, Lv, YP, Zhuang, Y, Chen, N, Guo, H, Yang, LY, Pang, KC, Guo, G, Shi, Y   +22 more
core   +1 more source

Characterization of Mycobacterium tuberculosis-specific Th22 cells and the effect of tuberculosis disease and HIV coinfection. [PDF]

, 2022
The development of a highly effective tuberculosis (TB) vaccine is likely dependent on our understanding of what constitutes a protective immune response to TB.
Mohau S Makatsa (13198572), F Millicent A Omondi (13198575), Wendy A Burgers (9093890), Rubina Bunjun (5705024), Robert J Wilkinson (8128959), Catherine Riou (164842)   +5 more
core   +1 more source

Non‐Invasive Scalp Tape‐Strip RNA Sequencing Captures Disease Activity and Treatment‐Response Signatures in Alopecia Areata

Allergy, EarlyView.
Non‐invasive scalp tape‐strip RNA sequencing captures core immune and follicular molecular signatures in alopecia areata. Tape‐strip transcriptomic profiles reflect disease severity and treatment response to baricitinib, with concordance to scalp biopsy‐derived signatures.
Carmen Mochón‐Jiménez, Jesús Gay‐Mimbrera, Viviana Dávila‐Flores, Helen He, Jerry Zhou, Irene Rivera‐Ruiz, Pedro J. Gómez‐Arias, Juan de Luque‐Fernández, Benjamin Ungar, Emma Guttman‐Yassky, Juan Ruano   +10 more
wiley   +1 more source

Helper T cell bias following tuberculosis chemotherapy identifies opportunities for therapeutic vaccination to prevent relapse

npj Vaccines, 2023
Therapeutic vaccines have promise as adjunctive treatment for tuberculosis (TB) or as preventives against TB relapse. An important development challenge is the limited understanding of T helper (Th) cell roles during these stages of disease.
Yazmin B. Martinez-Martinez, Matthew B. Huante, Sadhana Chauhan, Kubra F. Naqvi, Preeti Bharaj, Janice J. Endsley   +5 more
doaj   +1 more source

T Cell Microenvironmental Impacts and Therapeutic Opportunities: Application to Human Testicular Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Testicular germ cell tumors (TGCT) are the leading malignancy in adolescent and young adult males, yet the immunological and cellular mechanisms governing their tumor microenvironment (TME) remain poorly understood. Here, we present a comprehensive review of TGCT pathobiology with a focus on the immune landscape, particularly the role of tumor‐
R Islam, M Figura, J Heyer, S Lieber, M Huber, KL Loveland, HC Schuppe, Daniela Fietz   +7 more
wiley   +1 more source

Increased Peripheral Proinflammatory T Helper Subsets Contribute to Cardiovascular Complications in Diabetic Patients

Mediators of Inflammation, 2014
Background. Coronary atherosclerotic heart disease (CHD) is one of the major concerns in type 2 diabetes (T2D). The systemic chronic inflammation has been postulated to bridge the increased risk of cardiovascular disease and T2D.
Ru-xing Zhao, Wen-juan Li, Yi-ran Lu, Jun Qin, Chuan-long Wu, Meng Tian, Tian-yi He, Shou-nan Yi, Dong-qi Tang, Lei Sun, Li Chen   +10 more
doaj   +1 more source

A pro-inflammatory role for Th22 cells in Helicobacter pylori-associated gastritis [PDF]

Gut, 2014
Objective Helper T (Th) cell responses are critical for the pathogenesis of Helicobacter pylori-induced gastritis. Th22 cells represent a newly discovered Th cell subset, but their relevance to H. pylori-induced gastritis is unknown.
Zhuang, Y, Cheng, P, Liu, X-F, Peng, L-S, Li, B-S, Wang, T-T, Chen, N, Li, W-H, Shi, Y, Chen, W, Pang, KC, Zeng, M, Mao, X-H, Yang, S-M, Guo, H, Guo, G, Liu, T, Zuo, Q-F, Yang, H-J, Yang, L-Y, Mao, F-Y, Lv, Y-P, Zou, Q-M   +22 more
openaire   +3 more sources

Th17 but not Th22 cells display pathological behaviour in arthritis [PDF]

Annals of the Rheumatic Diseases, 2012
Background Th17 cells (IL-17+IL-22+) are critically involved in the induction and progression of arthritis. Recently, Th22 cells were discovered, which were characterised by IL-22 expression in the absence of IL-17. However, it remains unclear whether IL-22 and Th22 cells, directly contribute to synovial inflammation.
Jan Piet van Hamburg, Odilia B.J. Corneth, Sandra M.J. Paulissen, Nadine Davelaar, Patrick S. Asmawidjaja, Erik Lubberts   +5 more
openaire   +1 more source

Redefining “Comorbidity” in Dermatology: Beyond Terminology, Lessons From Other Specialties

JEADV Clinical Practice, EarlyView.
Patricia Garbayo‐Salmons, Mireia Moreno   +1 more
wiley   +1 more source