Results 71 to 80 of about 8,035 (194)

Increased AHR Transcripts Correlate With Pro-inflammatory T-Helper Lymphocytes Polarization in Both Metabolically Healthy Obesity and Type 2 Diabetic Patients

Frontiers in Immunology, 2020
Aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor whose transcription activity is regulated by small compounds provided by diet, xenobiotics, and metabolism.
Ru-xing Zhao, Ru-xing Zhao, Ru-xing Zhao, Qin He, Sha Sha, Jia Song, Jun Qin, Peng Liu, Yu-jing Sun, Lei Sun, Lei Sun, Xin-guo Hou, Xin-guo Hou, Xin-guo Hou, Li Chen, Li Chen, Li Chen   +16 more
doaj   +1 more source

Atherosclerosis: From Pathogenesis to Therapeutic Interventions

MedComm, Volume 7, Issue 11, November 2026.
The diagram outlines the core mechanisms driving atherosclerosis, including endothelial dysfunction, inflammatory responses, phenotypic switching of smooth muscle cells, and the gut–vascular axis. It also presents the corresponding therapeutic approaches now under development, such as gene therapies, immunotherapies, and nanotechnology platforms ...
Enge Zhou, Chenxi Zhan, Yuting Li, Yi Zeng, Renfei Luo, Xin Ouyang, Shixing Liu, Renqiang Yang, Nianlong Yan, Long Jiang   +9 more
wiley   +1 more source

T helper cell subsets specific for Pseudomonas aeruginosa in healthy individuals and patients with cystic fibrosis.

PLoS ONE, 2014
BackgroundWe set out to determine the magnitude of antigen-specific memory T helper cell responses to Pseudomonas aeruginosa in healthy humans and patients with cystic fibrosis.MethodsPeripheral blood human memory CD4(+) T cells were co-cultured with ...
Hannah K Bayes, Stephen Bicknell, Gordon MacGregor, Tom J Evans   +3 more
doaj   +1 more source

Th17 cells increase in RRMS as well as in SPMS, whereas various other phenotypes of Th17 increase in RRMS only

Multiple Sclerosis Journal - Experimental, Translational and Clinical, 2020
Background The nature and extent of inflammation seen in multiple sclerosis (MS) varies throughout the course of the disease. Changes seen in CD4+ T-helper cells in relapsing–remitting (RR) MS and secondary progressive (SP) MS might differ qualitatively ...
S Kalra, C Lowndes, L Durant, RC Strange, A Al-Araji, Clive P Hawkins, S John Curnow   +6 more
doaj   +1 more source

Circulating MicroRNA‐146a‐5p and MicroRNA‐143‐3p in Atopic Dermatitis—Atopic Comorbidities Matter

Allergy, EarlyView.
Karolina Dumycz, Thomas Welchowski, Yuxuan Deng, Sylvia Schnautz, Laura Maintz, Svenja Royeck, Anita Dreher, Claudio Rhyner, Thomas Bieber, Nadine Herrmann   +9 more
wiley   +1 more source

Liver Metastases from Colorectal Cancer: From Pathogenesis to Current Treatment

MedComm, Volume 7, Issue 10, October 2026.
The liver is not merely a passive recipient of disseminated tumor cells, but a unique metastatic organ shaped by anatomical, metabolic, and immunological characteristics that support tumor colonization. Increasing evidence indicates that colorectal cancer liver metastasis development is driven by dynamic interactions between tumor intrinsic programs ...
Jialiang Fan, Huiru Zhang, Deyang Kong, Yu Sun, Shuaibing Lu, Wenjing Yang, Renshen Xiang, Qi Zhang, Wei Pei, Haizeng Zhang, Lin Feng   +10 more
wiley   +1 more source

Elevated Th22 cells and related cytokines in patients with epithelial ovarian cancer

Medicine, 2017
This study is conducted to investigate the involvement of T-helper (Th) cells and regulatory T cells in epithelial ovarian cancer (EOC).The percentages of Th22, Th17, Th1, and regulatory T cells in the peripheral blood of EOC patients, benign ovarian epithelial neoplasm (BOEN) patients, and healthy control (HC) were examined by flow cytometry.
Wang, Ting, Zhang, Zhiwei, Xing, Huaixin, Wang, Li, Zhang, Guoxiang, Yu, Na, Wang, Junzhi, Guo, Wei, Jiang, Jie   +8 more
openaire   +2 more sources

Correlation between the percentages of Th22 cells and the percentages of Th17 cells in AS and RA patients.

, 2012
a, Positive correlation was found between Th22 cells and Th17 cells in AS patients. b, Positive correlation was found between Th22 cells and Th17 cells in RA patients.
Lei Qi (173882), Wei Li (7081), Yong-gang Li (173874), Dao-xin Ma (173898), Yu-hua Li (173879), Lei Zhang (38117), Zhen-feng Li (173904), Cun-zhong Yuan (173890), Xin-guang Liu (173886), Jian-min Li (173913), Nai-wen Hu (173892), Qiang Yang (135832)   +11 more
core   +1 more source

A pro-inflammatory role for Th22 cells in Helicobacter pylori-associated gastritis [PDF]

, 2015
OBJECTIVE: Helper T (Th) cell responses are critical for the pathogenesis of Helicobacter pylori-induced gastritis. Th22 cells represent a newly discovered Th cell subset, but their relevance to H. pylori-induced gastritis is unknown.
Wang, TT, Peng, LS, Liu, T, Mao, XH, Yang, HJ, Cheng, P, Li, BS, Li, WH, Chen, W, Zou, QM, Liu, XF, Zeng, M, Mao, FY, Yang, SM, Zuo, QF, Lv, YP, Zhuang, Y, Chen, N, Guo, H, Yang, LY, Pang, KC, Guo, G, Shi, Y   +22 more
core   +1 more source

Internal Structure, Kinematics, and Prehistory of Frozen Debris Lobe‐A (FDL‐A), Brooks Range, Alaska

Permafrost and Periglacial Processes, Volume 37, Issue 4, Page 645-667, October/December 2026.
ABSTRACT Frozen Debris Lobe‐A (FDL‐A)—one of hundreds of FDLs in the Brooks Range of northern Alaska—is a slow‐moving landslide in permafrost that has been the subject of research since 2008 due to its close proximity to the Dalton Highway. Here, we synthesize more than a decade's worth of climate and surface measurements of monitored FDLs, and the ...
Margaret M. Darrow, Esther L. Babcock, Ben A. Leshchinsky   +2 more
wiley   +1 more source