Results 121 to 130 of about 10,640,595 (395)
Allergology International, 2014 Background: In Th2 immune responses, TSLP is a key player by induction of OX40-ligand (OX40L) on dendritic cells (DCs), which is the trigger to induce Th2 cell-mediated allergic cascade.
Naoko Murakami-Satsutani +8 more
doaj +1 more source
Modeling the influence of TH1 and TH2 type cells in autoimmune diseases [PDF]
arXiv, 2000 A sharp TH1/TH2 dichotomy has often been used to define the effects of cytokines on autoimmune diseases. However contradictory results in recent research indicate that the situation may be more complex. We build here a simple mathematical model aimed at settling the contradictions.
arxiv
Advanced Functional Materials, Volume 35, Issue 15, April 10, 2025.Spider minor ampullate silk protein (MiSp) and retinoic acid (RA) based nanovaccine are capable of eliciting both mucosal and systemic immune responses following subcutaneous administration and demonstrate significant protective effects against CVB3 infection in mice.
Xingmei Qi +4 more
wiley +1 more source
Expression of Semaphorin4C by Th2-stimulated B cells [PDF]
Allergy, Asthma & Clinical Immunology, 2010 Background Semaphorins are a family of proteins implicated in neurogenesis, angiogenesis and axonal migration. Previous work from our laboratory has shown that Th2stimulated B cells express a unique semaphorin, SEMA4C. Given the roles of other semaphorins, we hypothesized that SEMA4C was expressed on Th2stimulated B cells and might play a role in B ...
Jean-Philippe Drolet +3 more
openaire +3 more sources
Advanced Functional Materials, EarlyView.This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley +1 more source
Recent Developments in Immune Network Theory including a concept for an HIV Vaccine [PDF]
arXiv, 2008 The symmetrical network theory is a framework for understanding the immune system, that dates back to the mid 1970s. The symmetrical network theory is based on symmetrical stimulatory, inhibitory and killing interactions between clones that are specific for each other.
arxiv
Treatment of allergic asthma: Modulation of Th2 cells and their responses
Respiratory Research, 2011 Atopic asthma is a chronic inflammatory pulmonary disease characterised by recurrent episodes of wheezy, laboured breathing with an underlying Th2 cell-mediated inflammatory response in the airways.
B. Bošnjak +3 more
semanticscholar +1 more source
A computational high-throughput screening approach of iNKT-agonists: a novel tool to find optimized iNKT cell ligands [PDF]
, 2013 Depending on the environment and the activating glycolipids, iNKT cells are known to induce T-helper 1 and/or T-helper 2 cytokines. This highly versatile nature makes these innate-like cells very interesting targets for immunomodulation.
ASPESLAGH, SANDRINE +8 more
core
Singling out Th2 cells in eosinophilic esophagitis [PDF]
Journal of Clinical Investigation, 2019 Eosinophilic esophagitis (EoE) is a recently described disease in which exposure to specific foods and allergens leads to type 2 inflammation, epithelial barrier dysfunction, and difficulty in swallowing. In the current issue of the JCI, Wen and colleagues investigate tissue T cell heterogeneity in patients with EoE using single-cell RNA sequencing ...
Walter L. Eckalbar, David J. Erle
openaire +5 more sources
Omnidirectional Transmissive Acoustic Metasurfaces Based on Goldberg Polyhedra
Advanced Functional Materials, EarlyView.This study introduces omnidirectional acoustic metasurfaces capable of manipulating wavefronts in multiple arbitrary directions simultaneously. A full‐stack pipeline for design, optimization, and fabrication is presented to construct near‐spherical holograms based on Goldberg polyhedra.
Andrea Achilleos +3 more
wiley +1 more source