Results 231 to 240 of about 10,640,595 (395)

MAGEA6 Engages a YY1‐Dependent Transcription to Dictate Perineural Invasion in Colorectal Cancer

Advanced Science, EarlyView.
This study investigates the role of MAGEA6 in perineural invasion (PNI) in colorectal cancer (CRC). MAGEA6 promotes CRC invasiveness by inhibiting YY1 ubiquitination, enhancing CXCL1 secretion, and recruiting Schwann cells. These findings highlight the potential of targeting the MAGEA6/YY1/CXCL1 axis for therapeutic strategies against PNI and tumor ...
Hao Wang, Kexin He, Ruixue Huo, Weihan Li, Shan Zhang, Lu‐Ju Jiang, Hao Wu, Minhao Yu, Shu‐Heng Jiang, Junli Xue   +9 more
wiley   +1 more source

Elevated Neddylation Pathway Promotes Th2 Cells Infiltration by Transactivating STAT5A in Hepatocellular Carcinoma. [PDF]

Front Oncol, 2021
Zhou L, Zhang L, Chen S, Sun D, Qu J.
europepmc   +1 more source

Expression and Function of CTLA-4 in Th1 and Th2 Cells [PDF]

, 1998
Maria‐Luisa Alegre, Helena Shiels, Craig B. Thompson, Thomas F. Gajewski   +3 more
openalex   +1 more source

Novel Bivalent mRNA‐LNP Vaccine for Highly Effective Protection against Pneumonic Plague

Advanced Science, EarlyView.
The study investigates mRNA‐lipid nanoparticle vaccines targeting Yersinia pestis, the causative agent of plague. Combined F1+LcrV mRNA vaccination elicited robust immune responses and protected mice against virulent wild‐type and atypical strains.
Uri Elia, Yinon Levy, Hila Cohen, Ayelet Zauberman, David Gur, Inbal Hazan‐Halevy, Moshe Aftalion, Shani Benarroch, Erez Bar‐Haim, Orit Redy‐Keisar, Ofer Cohen, Dan Peer, Emanuelle Mamroud   +12 more
wiley   +1 more source

BDNF Acts as a Prognostic Factor Associated with Tumor-Infiltrating Th2 Cells in Pancreatic Adenocarcinoma. [PDF]

Dis Markers, 2021
Zhu Y, Zhang C, Zhao D, Li W, Zhao Z, Yao S, Zhao D.   +6 more
europepmc   +1 more source

Anti-IL-4 antibody treatment prevents the induction of inflammatory bowel disease (IBD) in T-cell receptor (TCR) alpha chain-deficient (α−/−) mice by suppressing the effect of TH2 predominated CD4+ TCR βdim T cells

, 1998
Hiroshi Iijima, Isamu TAKAHASHI, Seiji Kawano, Kazuya Nagano, Makoto Hori, Hiroshi Kiyono   +5 more
openalex   +1 more source

Reciprocal Regulation of Th1- and Th2-Cytokine-Producing T Cells during Clearance of Parasitemia inPlasmodium falciparumMalaria [PDF]

, 1998
Stefan Winkler, Martin Willheim, Karin Baier, D. Scott Schmid, A Aichelburg, Wolfgang Graninger, Peter G. Kremsner   +6 more
openalex   +1 more source

Transcriptional Profiling of Th2 Cells Identifies Pathogenic Features Associated with Asthma

Journal of Immunology, 2016
G. Seumois, J. Zapardiel-Gonzalo, Brandie White, Divya Singh, V. Schulten, M. Dillon, D. Hinz, D. Broide, A. Sette, Bjoern Peters, P. Vijayanand   +10 more
semanticscholar   +1 more source

Integrating Aggregate Materials and Machine Learning Algorithms: Advancing Detection of Pathogen‐Derived Extracellular Vesicles

Aggregate, EarlyView.
Pathogen‐derived extracellular vesicle detection: theoretical insights and advanced methodologies: This review explores the theoretical foundations and practical applications of pEV detection, emphasizing the challenges and innovative strategies involving novel aggregate materials and machine learning for enhanced diagnostic accuracy.
Lihan Lai, Yun Su, Cong Hu, Zehong Peng, Wei Xue, Liang Dong, Tony Y. Hu   +6 more
wiley   +1 more source

IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases and is farnesoid X receptor responsive in NASH

Hepatology, EarlyView., 2022
IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases Abstract Background and Aims Pruritus is associated with multiple liver diseases, particularly those with cholestasis, but the mechanism remains incompletely understood.
Jun Xu, Ya Wang, Mina Khoshdeli, Matt Peach, Jen‐Chieh Chuang, Julie Lin, Wen‐Wei Tsai, Sangeetha Mahadevan, Wesley Minto, Lauri Diehl, Ruchi Gupta, Michael Trauner, Keyur Patel, Mazen Noureddin, Kris V. Kowdley, Aliya Gulamhusein, Christopher L. Bowlus, Ryan S. Huss, Robert P. Myers, Chuhan Chung, Andrew N. Billin   +20 more
wiley   +1 more source