Results 81 to 90 of about 55,234 (296)
Thalamic Circuit Diversity: Modulation of the Driver/Modulator Framework
Frontiers in Neural Circuits, 2016 The idea that dorsal thalamic inputs can be divided into drivers, which provide the primary excitatory drive for the relay of information to cortex, and modulators, which alter the gain of signal transmission, has provided a valuable organizing principle
Martha E Bickford
doaj +1 more source
Processing of analogy in the thalamocortical circuit [PDF]
, 2003 The corticothalamic feedback and the thalamic reticular nucleus have gained much attention lately because of their integrative and modulatory functions. A previous study by the author suggested that this circuitry can process analogies (i.e., the {\
Choe, Yoonsuck
core +2 more sources
Perspective: network-guided pattern formation of neural dynamics [PDF]
, 2014 The understanding of neural activity patterns is fundamentally linked to an understanding of how the brain's network architecture shapes dynamical processes.
Hilgetag, Claus C. +2 more
core +1 more source
A new interpretation of thalamocortical circuitry [PDF]
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2002 Almost all the information that is needed to specify thalamocortical and neocortical wiring derives from patterned electrical activity induced by the environment. Wiring accuracy must be limited by the anatomical specificity of the cascade of events triggered by neural activity and culminating in synaptogenesis. We present a simple model of learning in
Paul, Adams, Kingsley, Cox
openaire +2 more sources
The E3 Ubiquitin Ligase UBE3B Regulates Synaptic Development and Cortical Network Activity
Autism Research, EarlyView.ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impaired communication, abnormal social interactions, and restricted, repetitive behaviors. Pathogenic mutations in UBE3B result in neurodevelopmental disease, including intellectual disability, lack of speech, and ASD.
Shayal Vashisth +7 more
wiley +1 more source
Modeling the Possible Influences of Eye Movements on the Refinement of Cortical Direction Selectivity [PDF]
, 2004 The second-order statistics of neural activity was examined in a model of the cat LGN and V1 during free-viewing of natural images. In the model, the specific patterns of thalamocortical activity required for a Bebbian maturation of direction-selective ...
Parsons, Olga, Rucci, Michele
core +1 more source
Rodent somatosensory thalamocortical circuitry: neurons, synapses, and connectivity.
Neuroscience and Biobehavioral Reviews, 2020 As our understanding of the thalamocortical system deepens, the questions we face become more complex. Their investigation requires the adoption of novel experimental approaches complemented with increasingly sophisticated computational modeling. In this
C. O’Reilly +3 more
semanticscholar +1 more source
Serotonin 5‐HT7 receptor signaling in neuropsychiatric disorders
Bulletin of the Korean Chemical Society, EarlyView.5‐HT7R recruits Gs, G12, and β‐arrestin signaling to regulate neuronal plasticity, circuit function, and kinase‐linked intracellular responses. This review summarizes how these pathway‐selective modules contribute to autism spectrum disorder, depression, and schizophrenia, highlighting 5‐HT7R as a pathway‐informed therapeutic target. Abstract Serotonin
Eunseo Park, Hyunah Choo
wiley +1 more source
Gli2-Mediated Shh Signaling Is Required for Thalamocortical Projection Guidance
Frontiers in Neuroanatomy, 2022 The thalamocortical projections are part of the most important higher level processing connections in the vertebrates and follow a highly ordered pathway from their origin in the thalamus to the cerebral cortex. Their functional complexities are not only
Antuca Callejas-Marin +7 more
doaj +1 more source
Rapid Plasticity of Higher-Order Thalamocortical Inputs during Sensory Learning.
Neuron, 2019 Neocortical circuits are sensitive to experience, showing both anatomical and electrophysiological changes in response to altered sensory input. We examined input- and cell-type-specific changes in thalamo- and intracortical pathways during learning ...
N. Audette +4 more
semanticscholar +1 more source