Results 71 to 80 of about 5,799 (244)

PREGNANCY IN THALASSEMIA

Mediterranean Journal of Hematology and Infectious Diseases, 2019
Therapeutic advances, including the availability of oral iron chelators and new non-invasive methods for early detection and treatment of iron overload, have significantly improved the life expectancy and quality of life of patients with thalassemia, with a consequent increase in their reproductive potential and desire to have children.
Raffaella Origa, Federica Comitini
openaire   +4 more sources

Therapeutic Gene Editing: DNA Repair Pathways, Emerging Editors, and Clinical Progress

iNew Medicine, EarlyView.
ABSTRACT The field of gene editing has evolved rapidly over the past decade, progressing from programmable zinc‐finger nucleases (ZFNs) and transcription activator‐like effector nucleases (TALENs) to the widespread adoption of CRISPR‐Cas systems. First‐generation editors catalyzed genome engineering by introducing targeted double‐strand breaks (DSBs ...
Li‐Kuang Tsai, Youcai Xiong, Dongqi Liu, Dongshan Yang, Jifeng Zhang, Jie Xu, Renzhi Han, Y. Eugene Chen   +7 more
wiley   +1 more source

Inherited hemoglobin disorders in an Afro-Amazonian community: Saracura

Genetics and Molecular Biology, 2012
The most common hemoglobinopathies, viz, hemoglobins S and C, and α-and β-thalassemias, were investigated through the molecular screening of 116 subjects from the community of Saracura, comprising fugitive African slaves from farms of the ...
Greice Lemos Cardoso, Silvania Yukiko Lins Takanashi, João Farias Guerreiro   +2 more
doaj  

A kataláz enzim génje polimorfizmusának hatása az enzim expressziójára = Association of catalase gene and catalase protein expression [PDF]

, 2012
1. Kataláz gén exon 9 C111T polimorfizmus kismértékű vér kataláz csökkenéssel jár vitiligos nők esetében (CEMED 2011) 2. Csökkent vér kataláz aktivitás volt mérhető magyar beta-thalassemia trait betegeknél.
Góth, László, Káplár, Miklós, Shemirani, Amir Houshang, Simics, Enikő, Sükei, Eszter, Tarnai, Ildikó   +5 more
core  

Effect of Epigallocatechin‐3‐Gallate on Depression‐Related Cytokines in Thalassemia Patients: Molecular and Cellular Evaluation

Journal of Clinical Laboratory Analysis, EarlyView.
This study investigates the effects of Epigallocatechin‐3‐Gallate (EGCG), a potent anti‐inflammatory polyphenol isolated from Winged Marigold, on cytokine expression linked to depression in β‐thalassemia patients. EGCG demonstrated dose‐dependent suppression of key inflammatory cytokines (IL‐6, IL‐1β, TNF‐α, IFN‐γ) at both gene and protein levels ...
Mohammed N. Salman, Fouad Razzaq Al‐Burki, Hazim Ali Hussein, Laith A. Younus, Fadhil A. Nasser, Hasanain A. A. Almohseni   +5 more
wiley   +1 more source

Determinação da sobrecarga de ferro na talassemia pela IRM hepática e ferritina [PDF]

, 2008
Accumulation of iron in thalassemia causes organ damage and reduces patient survival due to heart lesions in the second decade of life. Iron deposits are monitored by direct (biopsy) and indirect methods (ferritin) with sequential data being better than ...
ANGULO, Ivan L., BAFFA, Oswaldo, CARNEIRO, Antonio A., COVAS, Dimas T., ELIAS JUNIOR, Jorge, VILELA, Guilherme   +5 more
core   +2 more sources

Impact of pre‐examination video education in Gd‐EOB‐DTPA‐enhanced liver MRI: A comparative study

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 34-41, March 2025.
This study evaluates the effects of pre‐examination video education on patient anxiety, satisfaction and image quality in Gd‐EOB‐DTPA‐enhanced liver MRI. We found that video education significantly reduced anxiety, increased patient satisfaction and improved image quality compared to standard pre‐MRI guidance, highlighting the potential of video ...
Hongfang Huang, Chenhui Li, Zisan Zeng, Junli Liang   +3 more
wiley   +1 more source

Genetic Disease Burden, Nutrition and Determinants of Tribal Health Care in Chhattisgarh State of Central-East India: A Status Paper [PDF]

, 2011
Tribal health is an important aspect of development and progress of the people. This study pertaining to genetic disease burden, nutritional status and biomedical anthropological assessment with particular reference to determinants of tribal health care ...
Balgir, RS
core   +1 more source

Dupilumab Treatment in Pemphigus: A Report of Three Cases and Literature Review

JEADV Clinical Practice, EarlyView.
ABSTRACT Pemphigus vulgaris (PV) and foliaceus (PF) are rare autoimmune blistering diseases traditionally treated with systemic corticosteroids, immunosuppressants, intravenous immunoglobulins, and rituximab. Nonetheless, a subset of patients remains refractory or has contraindications to these conventional therapies.
José Javier Mateos Rico, Marta Gutiérrez Pascual, María Dolores Caro Gutiérrez, Cristina Marcos Rodríguez, Javier de Quadros Malagón, Francisco Javier Vicente Martín   +5 more
wiley   +1 more source

Spectrum of hemoglobin variants in the population of northern region of West Bengal: An ethnogenetic proposition

Journal of Family Medicine and Primary Care, 2014
Context: The birth of transfusion-dependent states of hemoglobinopathies including thalassemias is preventable by population screening and genetic counseling.
Bidyut Krishna Goswami, Raghunath Pramanik, Sudipta Chakrabarty, Partha Pratim Pal, Sarama Banerjee, Arghya Bandyopadhyay   +5 more
doaj   +1 more source