Results 71 to 80 of about 2,702 (213)

Continuum of care after newborn screening for sickle cell disease: Multinational evidence from a systematic review and meta‐analysis

British Journal of Haematology, EarlyView.
Tanveer Rehman, Srijeeta Mitra, Kalpita Ganpat Gawit, Ravindra Kumar, Sritama Dutta, Ananya Anurakta Pattanaik, Lakhan Majhee, Tanu Anand, Manisha Madkaikar, Sanghamitra Pati   +9 more
wiley   +1 more source

What is the best approach to blood transfusion in sickle cell disease? A scientometric analysis and literature review

Transfusion Medicine, EarlyView.
Abstract Background Blood transfusion remains a cornerstone in the management of sickle cell disease (SCD); however, it is frequently complicated by red cell alloimmunisation. A significant debate persists within the scientific community regarding the optimal strategy to mitigate this risk: the traditional, pragmatic approach of serologic phenotyping ...
Christiane Ruffato Carminati, Lucas Fernandes Ananias, Saulo Fernando Moreira da Silva, Anna Cecília Dias Maciel Carneiro, Helio Moraes de Souza, Sarah Cristina Sato Vaz Tanaka, Fernanda Bernadelli De Vito   +6 more
wiley   +1 more source

Spectrum of thalassemias and hemoglobinopathies in West Bengal: A study of 90,210 cases by cation exchange high-performance liquid chromatography method over a period of 8 years

Journal of Applied Hematology, 2014
Background: Thalassemias and hemoglobinopathies are highly prevalent in India. Identification of these disorders is important for epidemiologic purposes and for prevention of thalassemia major and clinically severe hemoglobinopathies. Objectives: The aim
Santosh Kumar Mondal, Senjuti Dasgupta, Saikat Mondal, Nikhilesh Das   +3 more
doaj   +1 more source

Real‐world evidence supports the safety and efficacy profile of luspatercept in clinically complex and heavily iron‐overloaded patients

British Journal of Haematology, EarlyView.
Barbara Gianesin, Antonietta Zappu, Giovanni Battista Ferrero, Carmen Maria Gaglioti, Michele Santodirocco, Giuseppe Fania, Giovanna Graziadei, Daniele Lello Panzieri, Antonella Massa, Tommaso Mina, Francesca Polese, Angelantonio Vitucci, Francesco Arcioni, Maria Caterina Putti, Valerio Cecinati, Ilaria Fotzi, Paola Maria Grazia Sanna, Antonio Cappello, Filomena Longo, Roberto Lisi, Annamaria Pasanisi, Daniela Pietrasanta, Monica Bocchia, Elisa Bertoni, Antonella Cossu, Marilena Serra, Susanna Barella, Antonia Gigante, Gian Luca Forni, Raffaella Origa   +29 more
wiley   +1 more source

Persistent Hyperglycaemia and Transient Dysglycaemia in Tuberculosis: Evaluating the Bidirectional Interaction With Type‐2 Diabetes Mellitus and Clinical Outcomes

Tropical Medicine &International Health, EarlyView.
ABSTRACT Introduction Poor glycaemic control, indicated by a haemoglobin A1c (HbA1c) level of 7% or higher, increases the risk of active tuberculosis (TB) in patients with diabetes, while active TB can worsen glucose tolerance and insulin resistance, contributing to type‐2 diabetes mellitus (DM) progression.
Augustine Asare Boadu, Prince Asare, Michelle Yeboah‐Manu, Stephen Osei‐Wusu, Emelia Danso Konadu, Adwoa Asante‐Poku, Yayra Klinogo, Abraham Adjei, Desmond Omane Acheampong, Jane S. Afriyie‐Mensah, Dorothy Yeboah‐Manu, Yacoba Atiase   +11 more
wiley   +1 more source

EHA Research Roadmap on Hemoglobinopathies and Thalassemia: An Update

HemaSphere, 2019
. The inherited disorders of hemoglobin, which include sickle cell disease and thalassemias, are the most common and widespread distributed monogenic disorders.
Achille Iolascon, Lucia De Franceschi, Martina Muckenthaler, Ali Taher, David Rees, Mariane de Montalembert, Stefano Rivella, Androulla Eleftheriou, Maria Domenica Cappellini   +8 more
doaj   +1 more source

Establishment of MUi009 – A human induced pluripotent stem cells from a 32 year old male with homozygous β°-thalassemia coinherited with heterozygous α-thalassemia 2

Stem Cell Research, 2017
The thalassemias are a group of genetic disorders characterized by a deficiency in the synthesis of globin chains. In this study the MUi009-A human induced pluripotent stem cell line was successfully generated from peripheral blood CD34+ haematopoietic ...
Wasinee Wongkummool, Warun Maneepitasut, Pirut Tong-ngam, Amornrat Tangprasittipap, Thongperm Munkongdee, Chanikarn Boonchuay, Saovaros Svasti, Narisorn Kitiyanant, Kittiphong Paiboonsukwong, Suthat Fucharoen, Alisa Tubsuwan   +10 more
doaj   +1 more source

Addressing racial disparities in representation across blood, stem cell and organ and tissue donor pools

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Adequate representation of donors from diverse ancestral populations in blood, stem cell and organ transplantation is critical to ensuring equitable access to these lifesaving therapies. Because of population‐level differences in genetic markers, patients from racialized groups may have unique transfusion and ...
Bonnie Lu, Sylvia Okonofua, Farnaz Farahbakhsh, Rupal Hatkar, Lauren Sano, Margarita Conway, Marie‐Claire Kapesa, Manuel Escoto, Murdoch Leeies, Warren B. Fingrut   +9 more
wiley   +1 more source

Improved Outcomes for Older Children, Adolescents, and Young Adults With Neuroblastoma in the Post‐Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group

Pediatric Blood &Cancer, Volume 73, Issue 4, April 2026.
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell, Kavitha Srivatsa, Paola Angelini, Pei‐Chi Kao, Brady Payne, Arlene Naranjo, Sveva Castelli, Miho Kato, Miki Ohira, Ulriche Pöetschger, Yaël Mossé, Lucas Moreno, Meredith S. Irwin, Ramya Ramanujachar, Wendy B. London   +14 more
wiley   +1 more source

Molecular Diagnostics of ß-Thalassemia

Balkan Journal of Medical Genetics, 2012
A high-quality hemoglobinopathy diagnosis is based on the results of a number of tests including assays for molecular identification of causative mutations.
Plaseska-Karanfilska Dijana, Atanasovska B, Bozhinovski G, Chakalova L, Kocheva S, Karanfilski O   +5 more
doaj   +1 more source