Results 11 to 20 of about 63,898 (235)
New insight into teratogenic effects of (S)-thalidomide in zebrafish embryos growing inside the chorion and subjected to electric pulses [PDF]
Scientific ReportsStudies of (S)-thalidomide were conducted on zebrafish embryos subjected to electroporation processes using a square wave pulse generator. The results showed that the electroporation increases the absorption of (S)-thalidomide through the chorion into ...
Anna Małkowska +7 more
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Thalidomide in dermatology: revisited.
Indian journal of dermatology, 2015 The use of thalidomide in relation to dermatology is well- known and enough data is available in the literature about various aspects of thalidomide. Despite being an interesting and useful drug for many dermatoses, it is associated with many health hazards including the birth defects, phocomelia.
Iffat Hassan +2 more
openaire +5 more sources
Frontiers in Physiology, 2021 Peritoneal angiogenesis is the key pathophysiological factor that limits peritoneal ultrafiltration during peritoneal dialysis (PD) in uremic patients.
Nan Zhu +8 more
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Biological evaluation of both enantiomers of fluoro-thalidomide using human myeloma cell line H929 and others. [PDF]
PLoS ONE, 2017 Over the last few years, thalidomide has become one of the most important anti-tumour drugs for the treatment of relapsed-refractory multiple myeloma. However, besides its undesirable teratogenic side effect, its configurational instability critically ...
Etsuko Tokunaga +5 more
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Antiangiogenic Activity and in Silico Cereblon Binding Analysis of Novel Thalidomide Analogs
Molecules, 2020 Due to its antiangiogenic and anti-immunomodulatory activity, thalidomide continues to be of clinical interest despite its teratogenic actions, and efforts to synthesize safer, clinically active thalidomide analogs are continually underway. In this study,
Megan L. Peach +12 more
doaj +1 more source
Cells, 2023 Allergy is a chronic inflammatory disease, and its incidence has increased worldwide in recent years. Thalidomide, which was initially used as an anti-emetic drug but was withdrawn due to its teratogenic effects, is now used to treat blood cancers ...
Hyeun-Wook Chang +2 more
doaj +1 more source
Thalidomide inhibits alternative activation of macrophages in vivo and in vitro: a potential mechanism of anti-asthmatic effect of thalidomide. [PDF]
PLoS ONE, 2015 Thalidomide is known to have anti-inflammatory and immunomodulatory actions. However, the effect and the anti-asthmatic mechanism of thalidomide in the pathogenesis of asthmatic airways are not fully understood.This study is designed to determine the ...
Hyun Seung Lee +9 more
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